Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kathy Medvik"'
Autor:
Rajesh T. Gandhi, Lu Zheng, Ronald J. Bosch, Ellen S. Chan, David M. Margolis, Sarah Read, Beatrice Kallungal, Sarah Palmer, Kathy Medvik, Michael M. Lederman, Nadia Alatrakchi, Jeffrey M. Jacobson, Ann Wiegand, Mary Kearney, John M. Coffin, John W. Mellors, Joseph J. Eron
Publikováno v:
PLoS Medicine, Vol 8, Iss 8 (2011)
Externí odkaz:
https://doaj.org/article/f927af108d2c49179068595edb21d142
Autor:
Rajesh T Gandhi, Lu Zheng, Ronald J Bosch, Ellen S Chan, David M Margolis, Sarah Read, Beatrice Kallungal, Sarah Palmer, Kathy Medvik, Michael M Lederman, Nadia Alatrakchi, Jeffrey M Jacobson, Ann Wiegand, Mary Kearney, John M Coffin, John W Mellors, Joseph J Eron, AIDS Clinical Trials Group A5244 team
Publikováno v:
PLoS Medicine, Vol 7, Iss 8, p e1000321 (2010)
Most HIV-1-infected patients on effective antiretroviral therapy (ART) with plasma HIV-1 RNA levels below the detection limits of commercial assays have residual viremia measurable by more sensitive methods. We assessed whether adding raltegravir low
Externí odkaz:
https://doaj.org/article/ea37066179f74b4490ef6ff4cce51619
Autor:
Michael M. Lederman, M. R. Sandhya Rani, Benigno Rodriguez, Kathy Medvik, Sara J. Conry, Johan K. Sandberg, Alan L. Landay, Ronald E. Blanton, Yngve Falck-Ytter, Donald D. Anthony
Publikováno v:
The Journal of Infectious Diseases. 206:969-973
Disease progression of human immunodeficiency virus type 1 (HIV-1) is associated with immune activation. Activation indices are higher during coinfection of hepatitis C virus (HCV) and HIV. The effect of immune activation on interferon α (IFN-α) th
Autor:
Julie K. Jadlowsky, Ronald S. Veazey, Heather A. Pilch-Cooper, Thomas J. Hope, Mark R. Chance, Brian Clagett, Ronald G. Collman, Kathy Medvik, Valentina Mercanti, Nadeene E. Riddick, Michael M. Lederman, James A. Hoxie, Jean-Michel Escola, Scott F. Sieg, Ann Koons, Oliver Hartley, Donald E. Mosier, Robin E. Offord, Janna Kiselar
Publikováno v:
Blood, Vol. 118, No 4 (2011) pp. 1015-9
Blood
Blood
CC Chemokine Receptor 5 (CCR5) is an important mediator of chemotaxis and the primary coreceptor for HIV-1. A recent report by other researchers suggested that primary T cells harbor pools of intracellular CCR5. With the use of a series of complement
Autor:
Grace A, McComsey, Ulrich A, Walker, Chakra B, Budhathoki, Zhaohui, Su, Judith S, Currier, Lisa, Kosmiski, Linda G, Naini, Stéphannie, Charles, Kathy, Medvik, Judith A, Aberg, Jolene, Noel-Connor
Publikováno v:
AIDS. 24:2507-2515
Lipoatrophy is prevalent on thymidine nucleoside reverse transcriptase inhibitors (tNRTIs). A pilot trial showed that uridine (NucleomaxX) increased limb fat.A5229 was a multicenter trial in which HIV-infected individuals with lipoatrophy on tNRTI re
Publikováno v:
Clinical Immunology. 136:400-408
Immune reconstitution after HAART is incomplete, but no widely accepted method to quantify subclinical immune deficiency is available. We immunized 9 HIV-negative subjects and 29 HIV-infected patients with CD4>/=450 cells/microL and undetectable HIV
Autor:
John Spritzler, Angela Malaspina, Savita Pahwa, Evgenia Aga, Kathy Medvik, Catherine A. Battaglia, Alan L. Landay, Irini Sereti, Margaret A. Fischl, Richard M. Dunham, Michael A. Proschan, David M. Asmuth, Lawrence Fox, Michel Morre, Michael M. Lederman, John D. Altman, Allan R. Tenorio, Guido Silvestri, Susan Moir, Renaud Buffet
Publikováno v:
Blood. 113:6304-6314
Interleukin 7 (IL-7) is a common gamma chain receptor cytokine implicated in thymopoiesis and in peripheral expansion and survival of T lymphocytes. The safety and activity of recombinant human IL-7 (rhIL-7) administration were therefore examined in
Autor:
Kim Y. Smith, Pablo Tebas, Benigno Rodriguez, David M. Margolis, Hildegund C.J. Ertl, Anne Sevin, Kathy Medvik, Hernan Valdez, Hongying Wang, Laura M. Smeaton, Scott F. Sieg, Richard B. Pollard, Michael M. Lederman, Minya Pu
Publikováno v:
The Journal of Infectious Diseases. 194:1677-1685
Background. Although the determinants of immune deficiency and immune restoration in chronic human immunodeficiency virus (HIV)-1 infection are not well understood, immune activation has been proposed as being central to the pathogenesis of HIV. Meth
Autor:
Robert Asaad, Sandra J. Lee, Zhan Xu, Judy Lieberman, Hernan Valdez, Michael M. Lederman, Brooke Harnisch, Bruce K. Patterson, Kathy Medvik, Christoph Lange, Alan L. Landay
Publikováno v:
AIDS. 18:605-613
To ascertain whether lymphoproliferation (LP) responses to HIVp24 in chronically infected patients treated with antiretroviral therapy (ART) predict an improved cytolytic T-cell phenotype or better in vivo immune function as measured by immunization
Autor:
Michael M. Lederman, Kathy Medvik, Christoph Lange, Mary Wild, Robert Asaad, Robert C. Kalayjian, Hernan Valdez
Publikováno v:
AIDS. 17:2015-2023
OBJECTIVE To ascertain whether delaying the initiation of highly active antiretroviral therapy (HAART) compromises functional immune reconstitution in HIV-1 infection in persons who regain 'normal' CD4 T-cell counts after suppressive antiretroviral t