Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kathy L Frost"'
Autor:
Bryce M Warner, Derek R Stein, Rohit K Jangra, Megan M Slough, Patrycja Sroga, Angela Sloan, Kathy L Frost, Stephanie Booth, Kartik Chandran, David Safronetz
Publikováno v:
Viruses, Vol 11, Iss 7, p 645 (2019)
Andes virus (ANDV) and Sin Nombre virus (SNV) are the main causative agents responsible for hantavirus cardiopulmonary syndrome (HCPS) in the Americas. HCPS is a severe respiratory disease with a high fatality rate for which there are no approved the
Externí odkaz:
https://doaj.org/article/9ce9ee8a9bd0440bb083861ddee670ad
Autor:
Anna Majer, Sarah J Medina, Yulian Niu, Bernard Abrenica, Kathy J Manguiat, Kathy L Frost, Clark S Philipson, Debra L Sorensen, Stephanie A Booth
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003002 (2012)
Prion diseases typically have long pre-clinical incubation periods during which time the infectious prion particle and infectivity steadily propagate in the brain. Abnormal neuritic sprouting and synaptic deficits are apparent during pre-clinical dis
Externí odkaz:
https://doaj.org/article/ce34b49876464f819464ee9a0224b8bd
Autor:
Ebony N. Gary, Bryce M. Warner, Elizabeth M. Parzych, Bryan D. Griffin, Xizhou Zhu, Nikesh Tailor, Nicholas J. Tursi, Mable Chan, Mansi Purwar, Robert Vendramelli, Jihae Choi, Kathy L. Frost, Sophia Reeder, Kevin Liaw, Edgar Tello, Ali R. Ali, Kun Yun, Yanlong Pei, Sylvia P. Thomas, Amira D. Rghei, Matthew M. Guilleman, Kar Muthumani, Trevor Smith, Sarah K. Wootton, Ami Patel, David B. Weiner, Darwyn Kobasa
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102699- (2021)
Summary: More than 100 million people have been infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Common laboratory mice are not susceptible to wild-type SARS-CoV-2 infection, challenging the development and testing of effec
Externí odkaz:
https://doaj.org/article/c729d41c6d47484fbcc09aab37def4d6
Autor:
Lise Lamoureux, Babu Sajesh, Jessy A. Slota, Sarah J. Medina, Matthew Mayor, Kathy L. Frost, Bryce Warner, Kathy Manguiat, Heidi Wood, Darwyn Kobasa, Stephanie A. Booth
Publikováno v:
Viruses, Vol 14, Iss 6, p 1218 (2022)
The numerous neurological syndromes associated with COVID-19 implicate an effect of viral pathogenesis on neuronal function, yet reports of direct SARS-CoV-2 infection in the brain are conflicting. We used a well-established organotypic brain slice c
Externí odkaz:
https://doaj.org/article/c6ad9fd4d82c42a2bae92b7388f370d4
Publikováno v:
Frontiers in Neuroscience. 16
Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elusive. Here, we used RNAseq to profile transcription
Autor:
Debra L. Sorensen, Laura P. van Lieshout, James P. Bridges, Sarah K. Wootton, Ashley A. Stegelmeier, John J Lawder, Stephanie A. Booth, Tara N. Rindler, Kathy L. Frost
Publikováno v:
Gene Therapy. 30:236-244
Naturally occurring adeno-associated virus (AAV) serotypes that bind to ligands such as AVB sepharose or heparin can be purified by affinity chromatography, which is a more efficient and scalable method than gradient ultracentrifugation. Wild-type AA
Autor:
Jonathan Audet, Sarah K. Wootton, Byram W. Bridle, Lily Chan, Lisa A. Santry, Logan Banadyga, Emelissa J. Valcourt, Darwyn Kobasa, Leonardo Susta, Kathy L. Frost, Marnie Willman, Anders Leung, Jessica A. Minott, Robert C. Mould, Nikesh Tailor, Alixandra Albietz, Bryce M. Warner, Jason P. Knapp, Pierre Major, Yanlong Pei, Yeganeh Mehrani, Robert Vendramelli, Phuc H. Pham, Kevin Tierney, Alexander Leacy, Heidi Wood, Jacob G. E. Yates, Mable Chan, David Safronetz, Stephanie A. Booth, Shihua He, Bryan D. Griffin
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103219-(2021)
iScience, Vol 24, Iss 11, Pp 103219-(2021)
The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19). Worldwide efforts are being made to develop vaccines to mitigate this pandemic. We engineered two recombinant Newcastle dis
Autor:
Kevin Tierney, David Safronetz, Geoff Soule, Bryce M. Warner, Kathy L. Frost, Stephanie A. Booth, Derek R. Stein
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-7 (2019)
NPJ Vaccines
NPJ Vaccines
The World Health Organization has identified Lassa virus (LASV) as one of the top five pathogens to cause a severe outbreak in the near future. This study assesses the ability of a leading vaccine candidate, recombinant Vesicular stomatitis virus exp
Autor:
Sebastian Dowhanik, Kevin Tierney, Patrycja Sroga, Yvon Deschambault, Cody Buchanan, Greg Saturday, Derek R. Stein, Jonathan Audet, Logan Banadyga, Angela Sloan, Darwyn Kobasa, Oliver Lung, Bryce M. Warner, Dana P. Scott, Stephanie A. Booth, Vinayakumar Siragam, Guodong Liu, Bryan D. Griffin, Kathy L. Frost, David Safronetz
Publikováno v:
J Virol
Hantavirus cardiopulmonary syndrome (HCPS) is a severe respiratory disease caused by orthohantaviruses in the Americas with a fatality rate as high as 35%. In South America, Andes orthohantavirus (Hantaviridae, Orthohantavirus; ANDV) is a major cause
Autor:
David Safronetz, Kevin Tierney, Zhongde Wang, Jinxin Miao, Bryce M. Warner, Guillaume Poliquin, Kathy L. Frost, Kyle Rosenke, Stephanie A. Booth, Brian B. Gowen, Jonna B. Westover, Greg Saturday, Charlene Ranadheera, Heinz Feldmann, Emelissa J. Valcourt
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen causing a febrile illness in humans, which can progress to hemorrhagic manifestations, multi-organ failure, and death. Current mouse models of CCHFV infection reliably succumb to