Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Kathy L, McGraw"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/a2d554b53e2c4022bd94c8f6ac0de824
Autor:
Amy F. McLemore, Hsin-An Hou, Benjamin S. Meyer, Nghi B. Lam, Grace A. Ward, Amy L. Aldrich, Matthew A. Rodrigues, Alexis Vedder, Ling Zhang, Eric Padron, Nicole D. Vincelette, David A. Sallman, Omar Abdel-Wahab, Alan F. List, Kathy L. McGraw
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
NLRP3 inflammasome and IFN-stimulated gene (ISG) induction are key biological drivers of ineffective hematopoiesis and inflammation in myelodysplastic syndromes (MDSs). Gene mutations involving mRNA splicing and epigenetic regulatory pathways induce
Externí odkaz:
https://doaj.org/article/488f4e3ab6114c1b8723eabf8f2131c9
Autor:
Chen Wang, Kathy L. McGraw, Amy F. McLemore, Rami Komrokji, Ashley A. Basiorka, Najla Al Ali, Jeffrey E. Lancet, Eric Padron, Olivier Kosmider, Michaela Fontenay, Pierre Fenaux, Alan F. List, David A. Sallman
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/1398c5b136c14612b740e434506d113d
Autor:
Kathy L. McGraw, Chia-Ho Cheng, Y. Ann Chen, Hsin-An Hou, Björn Nilsson, Giulio Genovese, Thomas Cluzeau, Andrea Pellagatti, Bartlomiej P. Przychodzen, Mar Mallo, Leonor Arenillas, Azim Mohamedali, Lionel Adès, David A. Sallman, Eric Padron, Lubomir Sokol, Chimene Moreilhon, Sophie Raynaud, Hwei-Fang Tien, Jacqueline Boultwood, Benjamin L. Ebert, Francesc Sole, Pierre Fenaux, Ghulam J. Mufti, Jaroslaw P. Maciejewski, Peter A. Kanetsky, Alan F. List
Publikováno v:
Blood Advances, Vol 3, Iss 22, Pp 3579-3589 (2019)
Abstract: Myelodysplastic syndromes (MDS) are hematopoietic stem cell malignancies. Known predisposing factors to adult MDS include rare germline mutations, cytotoxic therapy, age-related clonal hematopoiesis, and autoimmune or chronic inflammatory d
Externí odkaz:
https://doaj.org/article/cf1ad2d32c354d1dad1743567cc1316e
Autor:
Amittha Wickrema, Amit Verma, Alan F. List, Sandeep Gurbuxani, Kathy L. McGraw, Tushar D. Bhagat, Hui Liu, Shanisha Gordon-Mitchell, Gaurav S. Choudhary, Jong Jin Jeong, Wen-Liang Kuo, Sriram Sundaravel
Supplemental figure 2: A) Flow cytometry analysis showing that the TF1 erythroleukemia cells express high levels of CD34 marker on their cell surface. B) Twenty four hours post DOCK4 siRNA nucleofection, cells were used for immunoblot analysis for DO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc46d466a91751aeb7f651b6ccafcd5
https://doi.org/10.1158/1078-0432.22471443
https://doi.org/10.1158/1078-0432.22471443
Autor:
Amittha Wickrema, Amit Verma, Alan F. List, Sandeep Gurbuxani, Kathy L. McGraw, Tushar D. Bhagat, Hui Liu, Shanisha Gordon-Mitchell, Gaurav S. Choudhary, Jong Jin Jeong, Wen-Liang Kuo, Sriram Sundaravel
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fa65a6632f060cb448e9383d80a705
https://doi.org/10.1158/1078-0432.22471431.v1
https://doi.org/10.1158/1078-0432.22471431.v1
Autor:
Amittha Wickrema, Amit Verma, Alan F. List, Sandeep Gurbuxani, Kathy L. McGraw, Tushar D. Bhagat, Hui Liu, Shanisha Gordon-Mitchell, Gaurav S. Choudhary, Jong Jin Jeong, Wen-Liang Kuo, Sriram Sundaravel
Purpose:Myelodysplastic syndromes (MDS) with deletion of chromosome 7q/7 [-7/(del)7q MDS] is associated with worse outcomes and needs novel insights into pathogenesis. Reduced expression of signaling protein dedicator of cytokinesis 4 (DOCK4) in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499d0d790ef44b791761d515bcffbed7
https://doi.org/10.1158/1078-0432.c.6527892.v1
https://doi.org/10.1158/1078-0432.c.6527892.v1
Autor:
Pedro Gonzalez-Menendez, Ira Phadke, Meagan E Olive, Axel Joly, Julien Papoin, Hongxia Yan, Jérémy Galtier, Jessica Platon, Sun Woo Sophie Kang, Kathy L. McGraw, Marie Daumur, Marie Pouzolles, Taisuke Kondo, Stéphanie Boireau, Franciane Paul, David J Young, Sylvain Lamure, Raghavendra G Mirmira, Anu Narla, Guillaume Cartron, Cynthia E. Dunbar, Myriam Boyer-Clavel, Natalie Porat-Shliom, Valerie Dardalhon, Valerie S Zimmermann, Marc Sitbon, Thomas Dever, Narla Mohandas, Lydie M Da Costa, Namrata D. Udeshi, Lionel Blanc, Sandrina Kinet, Naomi Taylor
Publikováno v:
Blood.
Metabolic programs contribute to hematopoietic stem and progenitor cell (HSPC) fate, but it is not known whether the metabolic regulation of protein synthesis controls HSPC differentiation. Here, we show that SLC7A1/CAT1-dependent arginine uptake and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f1feec8432b0b073149a78ea11d673
https://doi.org/10.1182/blood.2022017584
https://doi.org/10.1182/blood.2022017584
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d76c16ea51dc4906593459517b5367a2
https://doi.org/10.1007/978-1-0716-3040-2_7
https://doi.org/10.1007/978-1-0716-3040-2_7
Autor:
Thomas Cluzeau, Kathy L. McGraw, Brittany Irvine, Erico Masala, Lionel Ades, Ashley A. Basiorka, Jaroslaw Maciejewski, Patrick Auberger, Sheng Wei, Pierre Fenaux, Valeria Santini, Alan List
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Accumulating evidence implicates innate immune activation in the pathobiology of myelodysplastic syndromes. A key myeloid-related inflammatory protein, S100A9, serves as a Toll-like receptor ligand regulating tumor necrosis factor-α and interleukin-
Externí odkaz:
https://doaj.org/article/2427373ff50e41a9a337710595716baf