Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathy K.W. Au-Yeung"'
Publikováno v:
The American Journal of Chinese Medicine. 48:1179-1202
Over-expression of calpains in tumor tissues can be associated with cancer progression. Thus, inhibition of calpain activity using specific inhibitors has become a novel approach to control tumor growth. In this study, the anticancer potential of cry
Autor:
Kathy K.W. Au-Yeung, Joshua Ka-Shun Ko, Shiqing Zhang, Stephen Cho Wing Sze, Ken Kin Lam Yung, Zhu Zhang
Publikováno v:
Phytomedicine. 68:153177
Background Calycosin is a bioactive isoflavonoid of the medicinal plant Astragalus membranaceus that exhibits a wide range of pharmacological properties. In the present study, we have attempted to explore the anti-tumorigenic potential of calycosin i
Publikováno v:
Biochemical Journal. 398:73-82
Hyperhomocysteinaemia is an independent risk factor for cardiovascular diseases due to atherosclerosis. The development of atherosclerosis involves reactive oxygen species-induced oxidative stress in vascular cells. Our previous study [Wang and O (20
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 84:141-147
Folic acid supplementation is a promising approach for patients with cardiovascular diseases associated with hyperhomocysteinemia. We have demonstrated that homocysteine (Hcy) activates nuclear factor-κB (NF-κB), a transcription factor that plays a
Publikováno v:
Kidney International. 62(4):1160-1170
Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-κB. Background Renal ischemia/reperfusion injury is a major cause of acute renal failure in both native kidneys and renal allografts. One important f
Publikováno v:
Biochemical Pharmacology. 62:483-493
The activation of stress-activated protein (SAP) kinase may lead to an induction of apoptosis that is responsible for part of the cardiomyocyte death in reperfusion injury. The objective of the present study was to investigate the mechanism by which
Publikováno v:
Life Sciences. 68:903-912
Danshen, a Chinese herbal medicine has been widely used for the treatment of cardiovascular diseases. Magnesium tanshinoate B (MTB) is an active compound purified from Danshen. The objective of this study was to investigate the effect of MTB on the s
Publikováno v:
Circulation research. 94(1)
Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. Our previous studies demonstrated an important interaction between nuclear factor-κB (NF-κB) activation and homocysteine (Hcy)-induced chemokine expression in vascular
Publikováno v:
Clinical and experimental pharmacologyphysiology. 29(9)
1. Renal ischaemia followed by reperfusion leads to acute renal failure in both native kidneys and renal allografts. Cyclosporine A (CsA) has been used as an immunosuppressive agent in organ transplantation. In the present study, the effect of CsA on