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pro vyhledávání: '"Kathy Hotzel"'
Fibroblast growth factors (FGF) play important roles in development, angiogenesis, and cancer. FGF19 uniquely binds to FGF receptor 4 (FGFR4). Our previous study has shown that FGF19 transgenic tumors have an activated Wnt-pathway phenotype. Wnt sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8473f1014c4ac22d4faa02cc68f258c
https://doi.org/10.1158/0008-5472.c.6497124
https://doi.org/10.1158/0008-5472.c.6497124
Supplementary Table 1 from Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255be2f0f463f10d61befcdb48a916da
https://doi.org/10.1158/0008-5472.22373535
https://doi.org/10.1158/0008-5472.22373535
Supplementary Figure 1-8 from Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating β-Catenin Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2feb2dcee025f2b26a08de24316046e9
https://doi.org/10.1158/0008-5472.22373538
https://doi.org/10.1158/0008-5472.22373538
Publikováno v:
Journal of visualized experiments : JoVE. (185)
Positive and negative controls with known expression of target proteins are essential for the development of immunohistochemistry (IHC) assays. While tissue controls are beneficial for well-characterized proteins with defined tissue and cellular expr
Autor:
Amy E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, Benjamin I. Laufer, Oded Foreman, Mike Reichelt, Han Lin, Meredith Sagolla, Kathy Hötzel, Hai Ngu, Christoffer Soendergaard, Alberto Estevez, Hsiu-Chao Lin, Alexandre Goyon, Juan Bian, Jessica Lin, Flora I. Hinz, Brad A. Friedman, Amy Easton, Casper C. Hoogenraad
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 773-793 (2023)
Antisense oligonucleotide (ASO) therapeutics are being investigated for a broad range of neurological diseases. While ASOs have been effective in the clinic, improving productive ASO internalization into target cells remains a key area of focus in th
Externí odkaz:
https://doaj.org/article/3689714968e4460891db8a383fa60cf7
Autor:
Dorothy M French, Benjamin C Lin, Manping Wang, Camellia Adams, Theresa Shek, Kathy Hötzel, Brad Bolon, Ronald Ferrando, Craig Blackmore, Kurt Schroeder, Luis A Rodriguez, Maria Hristopoulos, Rayna Venook, Avi Ashkenazi, Luc R Desnoyers
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36713 (2012)
The fibroblast growth factor (FGF)-FGF receptor (FGFR) signaling system plays critical roles in a variety of normal developmental and physiological processes. It is also well documented that dysregulation of FGF-FGFR signaling may have important role
Externí odkaz:
https://doaj.org/article/ef355a6145de4eae90b1a7091709e19e