Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathy Hotz"'
Autor:
Amy E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, Benjamin I. Laufer, Oded Foreman, Mike Reichelt, Han Lin, Meredith Sagolla, Kathy Hötzel, Hai Ngu, Christoffer Soendergaard, Alberto Estevez, Hsiu-Chao Lin, Alexandre Goyon, Juan Bian, Jessica Lin, Flora I. Hinz, Brad A. Friedman, Amy Easton, Casper C. Hoogenraad
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 773-793 (2023)
Antisense oligonucleotide (ASO) therapeutics are being investigated for a broad range of neurological diseases. While ASOs have been effective in the clinic, improving productive ASO internalization into target cells remains a key area of focus in th
Externí odkaz:
https://doaj.org/article/3689714968e4460891db8a383fa60cf7
Autor:
Hongliang Cai, Nghia Nguyen, Deirdre Beaton La Placa, Shujuan Chen, Vincent Peterkin, Robert H. Tukey, Kathy Hotz, Young Sun Yang, Jeffrey C. Stevens
Publikováno v:
Drug Metabolism and Disposition. 38:879-886
Humanized mice that express the human UDP-glucuronosyltransferase (UGT) 1 locus have been developed in a Ugt1-null background as a model to improve predictions of human UGT1A-dependent drug clearance. Enzyme kinetic parameters (K(m) and V(max)) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770cc86df07bb79276fbcae4124d599e
https://doi.org/10.1124/dmd.109.030130
https://doi.org/10.1124/dmd.109.030130
Autor:
Dorothy M French, Benjamin C Lin, Manping Wang, Camellia Adams, Theresa Shek, Kathy Hötzel, Brad Bolon, Ronald Ferrando, Craig Blackmore, Kurt Schroeder, Luis A Rodriguez, Maria Hristopoulos, Rayna Venook, Avi Ashkenazi, Luc R Desnoyers
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36713 (2012)
The fibroblast growth factor (FGF)-FGF receptor (FGFR) signaling system plays critical roles in a variety of normal developmental and physiological processes. It is also well documented that dysregulation of FGF-FGFR signaling may have important role
Externí odkaz:
https://doaj.org/article/ef355a6145de4eae90b1a7091709e19e