Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathy Hilton"'
Autor:
Jacqueline E. Mermoud, Anne McLaren, Kathy Hilton, Neil Brockdorff, John R. Pehrson, M. Azim Surani, Tatyana B. Nesterova
Publikováno v:
Differentiation. 69:216-225
The molecular mechanism underlying X chromosome inactivation in female mammals involves the non-coding RNAs Xist and its antisense partner Tsix. Prior to X inactivation, these RNAs are transcribed in an unstable form from all X chromosomes, both in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15045b1a92151e61f7cadbb2c200d84
https://doi.org/10.1046/j.1432-0436.2002.690415.x
https://doi.org/10.1046/j.1432-0436.2002.690415.x
Autor:
Samuel Aparicio, Katharine L. Arney, Kathy Hilton, Sheila C. Barton, M. Azim Surani, Sanjeev Khosla, Rosalind M. John, Kelvin Hawker, Justin F. X. Ainscough
Publikováno v:
ResearcherID
Neuronatin (Nnat) is an imprinted gene that is expressed exclusively from the paternal allele while the maternal allele is silent and methylated. The Nnat locus exhibits some unique features compared with other imprinted domains. Unlike the majority
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159c22ee0592c9ea9b552f31574c2354
https://doi.org/10.1006/dbio.2001.0327
https://doi.org/10.1006/dbio.2001.0327
Autor:
Kathy Hilton, James D. Brenton, M.A. Surani, Robert A. Drewell, Justin F. X. Ainscough, S. Viville, Sheila C. Barton
Publikováno v:
Proceedings of the National Academy of Sciences. 96:9242-9247
The H19 gene is subject to genomic imprinting because it is methylated and repressed after paternal inheritance and is unmethylated and expressed after maternal inheritance. We recently identified a 1.1-kb control element in the upstream region of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40335c636e3f024a4391e0d407857f64
https://doi.org/10.1073/pnas.96.16.9242
https://doi.org/10.1073/pnas.96.16.9242
Publikováno v:
Scopus-Elsevier
There are distinctive and characteristic genomic modifications in primordial germ cells that distinguish the germ cell lineage from somatic cells. These modifications include, genome-wide demethylation, erasure of allele-specific methylation associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbaf5072cab44d6c0270e8f0ba72615
https://pubmed.ncbi.nlm.nih.gov/10101117
https://pubmed.ncbi.nlm.nih.gov/10101117
Autor:
Motoki N. Tada, Nobuo Takagi, M.A. Surani, Takashi Sado, Sheila C. Barton, Kathy Hilton, Takashi Tada
Publikováno v:
Development genes and evolution. 207(8)
Expression of imprinted genes is dependent on their parental origin. This is reflected in the heritable differential methylation of parental alleles. The gametic imprints are however reversible as they do not endure for more than one generation. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e51d42bb3c20d70863a2ca4f5f901f
https://pubmed.ncbi.nlm.nih.gov/9510550
https://pubmed.ncbi.nlm.nih.gov/9510550
Autor:
Hiroyuki Sasaki, Shirley M. Tilghman, Jennifer R. Saam, M. Azim Surani, Kathy Hilton, Mohamad Zubair
Publikováno v:
Genomics. 45(2)
The human L23 (mitochondrial)-related protein gene, located 40 kb downstream of the imprinted H19 gene, is biallelically expressed. We have cloned and characterized its mouse homolog, L23mrp, which maps to the conserved syntenic region on mouse chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bcc53abc90d1f4a7a1b6658e7e5b73
https://pubmed.ncbi.nlm.nih.gov/9344651
https://pubmed.ncbi.nlm.nih.gov/9344651
Autor:
Sheila C. Barton, M.A. Surani, Katharine L. Arney, Kathy Hilton, L. Dandolo, Justin F. X. Ainscough, Robert A. Drewell, James D. Brenton
Publikováno v:
Europe PubMed Central
The H19 imprinted gene is silenced when paternally inherited and active only when inherited maternally. This is thought to involve a cis-acting control region upstream of H19 that is responsible for regulating a number of functions including DNA meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4902605b8c3b413a8564553456e431e
http://europepmc.org/abstract/med/10903168
http://europepmc.org/abstract/med/10903168
