Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathy Hadje Georgiou"'
Publikováno v:
Organic Reactions. :565-1104
Publikováno v:
Tetrahedron. 73:853-858
The total syntheses of rotenone and munduserone are reported in this paper. The synthesis of rotenone involves two key transformations, the first of which is a Pd π-allyl mediated cyclisation for the construction of the dihydrobenzofuran skeleton. T
Autor:
Willem A. L. van Otterlo, Liliya V. Frolova, Madhuri Manpadi, Manuel A. Fernandes, Nikolai M. Evdokimov, Olivia L. George, Matthäus Getlik, Tiffany L. Kinnibrugh, Uma devi Bhoga, Wim F.A. Steelant, Steffen Renner, Alexander Kornienko, Hong Tang, Igor V. Magedov, Charles B. Shuster, Snezna Rogelj, Kathy Hadje Georgiou, Severine Van slambrouck
Publikováno v:
Journal of medicinal chemistry. 54(12)
Structural simplification of an antimitotic natural product podophyllotoxin with mimetic heterocyclic scaffolds constructed using multicomponent reactions led to the identification of compounds exhibiting low nanomolar antiproliferative and apoptosis