Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kathy H. Y. Shair"'
Publikováno v:
mSphere, Vol 4, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/d44826e4a1414c408f9e170687c00b53
Publikováno v:
mSphere, Vol 3, Iss 4 (2018)
ABSTRACT Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that establishes a latent reservoir in peripheral B-lymphocytes with sporadic reactivation. EBV also infects epithelial cells, predominantly resulting in a lytic infection, which may
Externí odkaz:
https://doaj.org/article/a451793b21ba4d6a8efd7540eb36d6d5
Autor:
Elizabeth A. Caves, Rachel M. Butch, Sarah A. Cook, Laura R. Wasil, Chen Chen, Yuanpu Peter Di, Nara Lee, Kathy H. Y. Shair
Publikováno v:
mSphere, Vol 2, Iss 6 (2017)
ABSTRACT Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that persistently infects humans, with nearly 95% seropositivity in adults. Infection in differentiating epithelia is permissive, but EBV-associated nasopharyngeal carcinoma (NPC) tum
Externí odkaz:
https://doaj.org/article/ead35caec1924fa593e364da3b73822f
Autor:
Kathy H. Y. Shair, Nancy Raab-Traub
Publikováno v:
mBio, Vol 3, Iss 5 (2012)
ABSTRACT Latent membrane protein 1 (LMP1) and LMP2A affect cell growth in both epithelial cells and lymphocytes. In this study, the effects on cellular gene expression were determined by microarray analysis of transgenic mice expressing LMP1, LMP2A,
Externí odkaz:
https://doaj.org/article/a2a86712c3674bdc81b140e386c8141c
Autor:
Kathy H. Y. Shair
Publikováno v:
mSphere
mSphere, Vol 5, Iss 5 (2020)
mSphere, Vol 5, Iss 5 (2020)
Kathy Shair works in the field of Epstein-Barr virus (EBV)-associated cancers, with emphasis on nasopharyngeal carcinoma (NPC). In this mSphere of Influence article, she reflects on how the paper “Efficient replication of Epstein-Barr virus in stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a6a9abc2bc53fef37b7e067a3682bb
https://pubmed.ncbi.nlm.nih.gov/32968011
https://pubmed.ncbi.nlm.nih.gov/32968011
Autor:
Stella E. Lee, Hyun Jung Park, Ka-Wei Tang, John A. Moore, Phillip Ziegler, Sanna Abrahamsson, Kathy H. Y. Shair, Yarong Tian, Michael M. Myerburg, Anthony Green, Yulong Bai
Epstein-Barr virus (EBV) infection is ubiquitous in humans and is associated with the cancer, nasopharyngeal carcinoma. EBV replicates in the differentiated layers of stratified keratinocytes but whether the other cell types of the airway epithelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3612e6332a99af2371a096ae1d9e01c
https://doi.org/10.1101/2020.08.31.272096
https://doi.org/10.1101/2020.08.31.272096
Autor:
Misbah El-Jesr, Bruno Hernáez, Cornelius Fischer, Antonio Alcami, Sascha Sauer, Kathy H. Y. Shair, Iliana Georgana, Rocío Martín, Graciela Alonso, Carlos Maluquer de Motes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Science Advances
instname
Science Advances
DNA sensing inhibition by viral cGAMP nuclease impairs anti-viral responses and protective immunity.
Cells contain numerous immune sensors to detect virus infection. The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and activat
Cells contain numerous immune sensors to detect virus infection. The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4728550d6d9182fcfb1f9822b86f6235
http://hdl.handle.net/10261/239491
http://hdl.handle.net/10261/239491
Autor:
Kathy H Y Shair, Katherine M Bendt, Rachel H Edwards, Elisabeth C Bedford, Judith N Nielsen, Nancy Raab-Traub
Publikováno v:
PLoS Pathogens, Vol 3, Iss 11, p e166 (2007)
Latent membrane protein 1 (LMP1) is the major oncoprotein of Epstein-Barr virus (EBV). In transgenic mice, LMP1 promotes increased lymphoma development by 12 mo of age. This study reveals that lymphoma develops in B-1a lymphocytes, a population that
Externí odkaz:
https://doaj.org/article/85cc1172d921490798d94692badeddc0
Autor:
Nara Lee, Kathy H. Y. Shair, Simon C. Watkins, Donna Stoltz, Sarah A. Cook, Elizabeth A. Caves
Publikováno v:
mSphere
mSphere, Vol 4, Iss 2, p e00247-19 (2019)
mSphere, Vol 4, Iss 2 (2019)
mSphere, Vol 4, Iss 2, p e00247-19 (2019)
mSphere, Vol 4, Iss 2 (2019)
Lifting adherent cells to the air-liquid interface (ALI) is a method conventionally used to culture airway epithelial cells into polarized apical and basolateral surfaces. Reactivation of Epstein-Barr virus (EBV) from monolayer epithelial cultures is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434164d24dd69af4c905db91526738f5
https://pubmed.ncbi.nlm.nih.gov/30021875
https://pubmed.ncbi.nlm.nih.gov/30021875
Autor:
Alex S. Reznik, Kathy H. Y. Shair, Yarong Tian, Ka-Wei Tang, Anthony Green, Phillip Ziegler, Sanna Abrahamsson, John A. Moore, Michael M. Myerburg, Yulong Bai, Stella E. Lee, Hyun Jung Park, Alan Bäckerholm
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009041 (2021)
PLoS Pathogens, Vol 17, Iss 4, p e1009041 (2021)
Epstein-Barr virus (EBV) is a ubiquitous γ-herpesvirus with latent and lytic cycles. EBV replicates in the stratified epithelium but the nasopharynx is also composed of pseudostratified epithelium with distinct cell types. Latent infection is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f176246e55c5eacad8160cf0009f238
https://doi.org/10.1371/journal.ppat.1009041
https://doi.org/10.1371/journal.ppat.1009041