Zobrazeno 1 - 10
of 481
pro vyhledávání: '"Kathy D, Miller"'
Autor:
Toshio Shimizu, John Powderly, Albiruni Abdul Razak, Patricia LoRusso, Kathy D. Miller, Steven Kao, Sarah Kongpachith, Catherine Tribouley, Michelle Graham, Brian Stoll, Maulik Patel, Mohammad Sahtout, Martha Blaney, Rachel Leibman, Talia Golan, Anthony Tolcher
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundTransforming growth factor (TGF)-ß1 is a pleiotropic cytokine that can promote tumor growth and suppress antitumor immune responses. Latent TGF-ß1 associates with glycoprotein-A repetition predominant (GARP) on the surface of regulatory T
Externí odkaz:
https://doaj.org/article/ecaf119bc00648e1807c616981421d5c
Autor:
Brijesh Kumar, Aditi S. Khatpe, Jiang Guanglong, Katie Batic, Poornima Bhat-Nakshatri, Maggie M. Granatir, Rebekah Joann Addison, Megan Szymanski, Lee Ann Baldridge, Constance J. Temm, George Sandusky, Sandra K. Althouse, Michele L. Cote, Kathy D. Miller, Anna Maria Storniolo, Harikrishna Nakshatri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to ductal epithelial ce
Externí odkaz:
https://doaj.org/article/75421f2ad75f4636aa0061e39d6146f1
Autor:
Stefania Pianetti, Kathy D. Miller, Hannah H. Chen, Sandra Althouse, Sha Cao, Steven J. Michael, Gail E. Sonenshein, Nora D. Mineva
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Breast malignancies are the predominant cancer-related cause of death in women. New methods of diagnosis, prognosis and treatment are necessary. Previously, we identified the breast cancer cell surface protein ADAM8 as a marker of
Externí odkaz:
https://doaj.org/article/5cc491d6eaf74f3fb9dbdc1607f532c5
Autor:
Joseph A. Sparano, Anne O’Neill, Noah Graham, Donald W. Northfelt, Chau T. Dang, Antonio C. Wolff, George W. Sledge, Kathy D. Miller
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Systemic inflammation is believed to contribute to the distant recurrence of breast cancer. We evaluated serum samples obtained at diagnosis from 249 case:control pairs with stage II-III Her2-negative breast cancer with or without subsequent
Externí odkaz:
https://doaj.org/article/3741cea676a84aada2335dfb8178147f
Autor:
Wintana Balema, Diane Liu, Yu Shen, Randa El‐Zein, Bisrat G. Debeb, Megumi Kai, Beth Overmoyer, Kathy D. Miller, Huong T. Le‐Petross, Naoto T. Ueno, Wendy A. Woodward
Publikováno v:
Cancer Medicine, Vol 10, Iss 18, Pp 6261-6272 (2021)
Abstract Background Inflammatory breast cancer (IBC) is a clinical diagnosis. Here, we examined the association of a “classic” triad of clinical signs, swollen involved breast, nipple change, and diffuse skin change, with overall survival (OS). M
Externí odkaz:
https://doaj.org/article/71742e0526d545248a9ccf667e9f4628
Autor:
Maitri Kalra, Yan Tong, David R. Jones, Tom Walsh, Michael A. Danso, Cynthia X. Ma, Paula Silverman, Mary-Claire King, Sunil S. Badve, Susan M. Perkins, Kathy D. Miller
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Patients with triple-negative breast cancer (TNBC) who have residual disease after neoadjuvant therapy have a high risk of recurrence. We tested the impact of DNA-damaging chemotherapy alone or with PARP inhibition in this high-risk populati
Externí odkaz:
https://doaj.org/article/5b3db53e4cb24f2c9c8cea80e9eb7951
Autor:
Laura Q Rogers, Stephen J Carter, Marissa N Baranauskas, Tarah J Ballinger, Kathy D Miller, Dustin C Nabhan
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 7, Iss 3 (2021)
Whether slowing disease progression or combatting the ills of advancing age, the extensive utility of exercise training has contributed to the outright declaration by the American College of Sports Medicine that ‘exercise is medicine’. Consistent
Externí odkaz:
https://doaj.org/article/864ac99f244949f3888f4918f8e8db9e
Autor:
Bradley A. Hancock, Yu-Hsiang Chen, Jeffrey P. Solzak, Mufti N. Ahmad, David C. Wedge, Dumitru Brinza, Charles Scafe, James Veitch, Rajesh Gottimukkala, Walt Short, Rutuja V. Atale, Mircea Ivan, Sunil S. Badve, Bryan P. Schneider, Xiongbin Lu, Kathy D. Miller, Milan Radovich
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background Approximately two thirds of patients with localized triple-negative breast cancer (TNBC) harbor residual disease (RD) after neoadjuvant chemotherapy (NAC) and have a high risk-of-recurrence. Targeted therapeutic development for TN
Externí odkaz:
https://doaj.org/article/95c68e264d6a482f9c40b34a6e243f96
Autor:
Fei Shen, Guanglong Jiang, Santosh Philips, Laura Gardner, Gloria Xue, Erica Cantor, Reynold C. Ly, Wilberforce Osei, Xi Wu, Chau Dang, Donald Northfelt, Todd Skaar, Kathy D. Miller, George W. Sledge, Bryan P. Schneider
Publikováno v:
Clinical Cancer Research. :OF1-OF7
Purpose: Paclitaxel is a widely used anticancer therapeutic. Peripheral neuropathy is the dose-limiting toxicity and negatively impacts quality of life. Rare germline gene markers were evaluated for predicting severe taxane-induced peripheral neuropa
Autor:
Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:1345-1360
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an