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pro vyhledávání: '"Kathy Coen"'
Role of the kappa-opioid receptor system in stress-induced reinstatement of nicotine seeking in rats
Publikováno v:
Behavioural Brain Research. 265:188-197
Rationale The correlation between stress and smoking is well established. The mechanisms that underlie this relationship are, however, unclear. Recent data suggest that the kappa-opioid system is involved in the mediation of negative affective states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2449817fef4cba25377ad9283c51bb15
https://doi.org/10.1016/j.bbr.2014.02.029
https://doi.org/10.1016/j.bbr.2014.02.029
The CYP2B enzyme is expressed in human and rat brain, and metabolizes many CNS-acting drugs. The gene that encodes human CYP2B6 is highly polymorphic, where the variation in brain enzyme levels could result in altered brain drug levels. CYP2B can met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1dc711d52a2b81a44474d5b5db4bf0d
https://europepmc.org/articles/PMC4839514/
https://europepmc.org/articles/PMC4839514/
Publikováno v:
Neuroscience letters. 444(3)
A marked heterogeneity exists among stressors in their ability to reinstate alcohol seeking in rats. We have reported that the pharmacological stressor yohimbine, an alpha-2 adrenoceptor antagonist, potently reinstated alcohol seeking, but FG-7142, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63dfb78a84e3a5889987ff557f8ce2e7
https://pubmed.ncbi.nlm.nih.gov/18755245
https://pubmed.ncbi.nlm.nih.gov/18755245