Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kathy Carroll"'
Publikováno v:
Toxicology in Vitro. 14:101-115
Primary rat hepatocytes were cultured under various matrix and media conditions and examined after 1 week for the expression and regulation of cytosolic glutathione S-transferase (GST) enzymes. Striking effects on cell morphology were observed in rel
Autor:
Maciej, Czerwinski, Peter, Opdam, Ajay, Madan, Kathy, Carroll, Daniel R, Mudra, Lawrence L, Gan, Gang, Luo, Andrew, Parkinson
Publikováno v:
Methods in enzymology. 357
Autor:
Ajay Madan, Linda A. Krueger, Christopher Chengelis, Dan Mudra, Kathy Carroll, April Downey, Richard A. Graham, Andrew Parkinson
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 30(11)
The aim of this study was to determine the in vitro and in vivo effects of several prototypical inducers, namely beta-naphthoflavone, 3-methylcholanthrene, phenobarbital, isoniazid, rifampin, and clofibric acid, on the expression of cytochrome P450 (
Autor:
Tim Burn, April Downey, Michael Sinz, Gang Luo, Summer Jolley, Liang-Shang Gan, Kathy Carroll, Christopher Rizzo, Richard A. Graham, Darryl Gilbert, Geraldine A. Hamilton, Jianrong Lin, Edward L. LeCluyse, Dave Christ, Andrew Parkinson, Sean Kim, Mark R. Cunningham, Ajay Madan, Bernard H. Selling, Jindong Xie, Daniel R. Mudra
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 30(7)
Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary culture of human hepatocytes and measuring CYP3A4 mRNA, protein and microsomal activity. Recently a pregnane X receptor (PXR) reporter gene assay was established t
Autor:
Lawrence L Gan, Peter Opdam, Maciej Czerwinski, Daniel R. Mudra, Gang Luo, Ajay Madan, Andrew Parkinson, Kathy Carroll
Publisher Summary The branched DNA (bDNA) signal amplification assay provides a sensitive and relatively straightforward method for quantifying the levels of specific mRNAs. The cytochrome P450 (CYP) induction studies performed in laboratory with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00f28f73577ddb84e695c8bf1488ce4
https://doi.org/10.1016/s0076-6879(02)57676-x
https://doi.org/10.1016/s0076-6879(02)57676-x
Publikováno v:
The Pediatric infectious disease journal. 13(9)
Autor:
V. Katherine Gray, Kathy Carroll Bs
Publikováno v:
Clinical Gerontologist. 1:19-30
A preliminary study was conducted in a SNF to observe the behaviors of severely impaired residents in both segregated and integrated groups. The results suggest that integrating individuals with varying levels of cognitive ability can improve the fun
Autor:
A, Graham Richard, April, Downey, Dan, Mudra, Linda, Krueger, Kathy, Carroll, Christopher, Chengelis, Ajay, Madan, Andrew, Parkinson
Publikováno v:
Drug Metabolism and Disposition; November 2002, Vol. 30 Issue: 11 p1206-13, 8p
Autor:
Gang, Luo, Mark, Cunningham, Sean, Kim, Tim, Burn, Jianrong, Lin, Michael, Sinz, Geraldine, Hamilton, Christopher, Rizzo, Summer, Jolley, Darryl, Gilbert, April, Downey, Daniel, Mudra, Richard, Graham, Kathy, Carroll, Jindong, Xie, Ajay, Madan, Andrew, Parkinson, Dave, Christ, Bernard, Selling, Edward, LeCluyse, Liang-Shang, Gan
Publikováno v:
Drug Metabolism and Disposition; July 2002, Vol. 30 Issue: 7 p795-804, 10p
Publikováno v:
Scopus-Elsevier
The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66db9683aa8effd35f699c84ec548aaa
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033655573&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033655573&partnerID=MN8TOARS