Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kathy A. Joyce"'
Autor:
David Husband, M Moxham, Triantafillos Liloglou, Farida Alam, Brian Haylock, Carol Walker, Atik Baborie, Helen Wong, Julie R. Dunn, Andrew Brodbelt, R Sibson, Kathy A. Joyce, Daniel Crooks, Aditya Shenoy
Publikováno v:
British Journal of Cancer
Background: Epigenetic silencing of O6-methylguanine-DNA-methyltransferase (MGMT) by promoter methylation is associated with improved survival in glioblastomas treated with alkylating agents. In this study, we investigated MGMT promoter methylation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8177faf50fdc41cd35a13246a18df96a
http://europepmc.org/articles/PMC2713697
http://europepmc.org/articles/PMC2713697
Autor:
J Prosser, Brian Haylock, David L Fildes, K. Kopitzki, Carol Walker, Sobhan Vinjamuri, David Husband, Kathy A. Joyce, Michael D. Jenkinson, D. G. Du Plessis, John Broome, Peter C. Warnke, Trevor A Smith
Publikováno v:
British Journal of Cancer
The -1p/-19q genotype predicts chemosensitivity in oligodendroglial neoplasms, but some with intact 1p/19q also respond and not all with 1p/19q loss derive durable benefit from chemotherapy. We have evaluated the predictive and prognostic significanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7c479a5cb0b680f939180de5be145e
https://doi.org/10.1038/sj.bjc.6603390
https://doi.org/10.1038/sj.bjc.6603390
Autor:
Brian Haylock, John Broome, Michael D. Jenkinson, David Husband, Daniel du Plessis, Kathy A. Joyce, Carol Walker, Peter C. Warnke, Trevor S. Smith, Diane Fildes
Publikováno v:
Neuroradiology
Introduction The biological factors responsible for differential chemoresponsiveness in oligodendroglial tumours with or without the −1p/−19q genotype are unknown, but tumour vascularity may contribute. We aimed to determine whether dynamic susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae08be47b87724f8ac9760d86316493a
https://doi.org/10.1007/s00234-006-0122-z
https://doi.org/10.1007/s00234-006-0122-z
Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI features
Autor:
Peter C. Warnke, Kathy A. Joyce, Michael D. Jenkinson, Carol Walker, Trevor S. Smith, Daniel du Plessis
Publikováno v:
Brain. 129:1884-1891
Oligodendroglial neoplasms with the -1p/-19q genotype are more indolent with longer survival and increased therapeutic responsiveness than those with intact 1p/19q, but the biological basis for these clinical differences is unclear. Recent research s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47705c6df3e63f999c2dad463456395
https://doi.org/10.1093/brain/awl108
https://doi.org/10.1093/brain/awl108
Autor:
Michael D. Jenkinson, Brian Haylock, Peter C. Warnke, Kathy A. Joyce, David Husband, Carol Walker, Trevor R.F. Smith, John Broome, D. G. Du Plessis, Diane Fildes
Publikováno v:
Neurology. 66:1661-1667
The -1p/-19q genotype has been associated with prolonged survival and chemosensitivity in oligodendroglial neoplasms, but the predictive and prognostic significance of genotype in the routine clinic is not established.The authors investigated allelic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de9f8b23478ce9df103aca5614dcc75
https://doi.org/10.1212/01.wnl.0000218270.12495.9a
https://doi.org/10.1212/01.wnl.0000218270.12495.9a
Publikováno v:
Neuropathology and Applied Neurobiology. 26:441-447
Investigation of the clinical significance of genetic alterations in gliomas requires molecular genetic analysis using samples from retrospective or prospective clinical studies. However, diagnostic tissue is often severely limited and because of fix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a97f9cb536fa6f2f98825838e5f2540c
https://doi.org/10.1046/j.1365-2990.2000.00272.x
https://doi.org/10.1046/j.1365-2990.2000.00272.x
Cellularity and apparent diffusion coefficient in oligodendroglial tumours characterized by genotype
Autor:
Kathy A. Joyce, Trevor S. Smith, Michael D. Jenkinson, Daniel du Plessis, Carol Walker, Andrew Brodbelt
Publikováno v:
Journal of neuro-oncology. 96(3)
Purpose Apparent diffusion coefficient (ADC) describes water diffusion within tissues. Previous studies report a negative linear correlation between minimum ADC and tumour cellularity in different types of gliomas, but there are no studies in oligode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7f622d237a0e928a96a2d0a39b2d97
https://pubmed.ncbi.nlm.nih.gov/19618117
https://pubmed.ncbi.nlm.nih.gov/19618117
Autor:
Trevor S. Smith, Michael D. Jenkinson, Andrew Brodbelt, Kathy A. Joyce, Carol Walker, Peter C. Warnke
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 26(6)
Purpose To investigate whether oligodendroglial tumors with or without 1p/19q loss differ in their diffusion-weighted imaging characteristics. Oligodendroglial tumors with or without 1p/19q loss differ in their therapeutic responsiveness and prognosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e836fd8de405175d04c486b178f0005a
https://pubmed.ncbi.nlm.nih.gov/17968881
https://pubmed.ncbi.nlm.nih.gov/17968881
Autor:
Diane Fildes, Kathy A. Joyce, Carol Walker, Peter C. Warnke, Trevor S. Smith, D. G. Du Plessis, Michael D. Jenkinson
Publikováno v:
Neurology. 64(12)
Background: Oligodendroglial neoplasms with combined loss of chromosomes 1p and 19q may have a good prognosis and respond to procarbazine-lomustine (CCNU)-vincristine(PCV) chemotherapy.Objective: To determine whether single voxel magnetic resonance s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e57febc26dd24eff24882c85409f5b6
https://pubmed.ncbi.nlm.nih.gov/15985578
https://pubmed.ncbi.nlm.nih.gov/15985578
Autor:
Diane Fildes, Abigail Gee, Brian Haylock, David Husband, John Broome, Daniel du Plessis, Peter C. Warnke, Kathy A. Joyce, Trevor S. Smith, Carol Walker
Publikováno v:
Annals of neurology. 57(6)
To evaluate the role of molecular genetics in the routine clinic, we investigated allelic imbalance at 1p36, 19q13, 17p13, 10p12-15, and 10q22-26 and p53 mutation in 100 oligodendroglial neoplasms diagnosed at a single treatment center between 2000 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f3854cfb125fcd000478d35eef628b
https://pubmed.ncbi.nlm.nih.gov/15929038
https://pubmed.ncbi.nlm.nih.gov/15929038