Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kathy, Hince"'
Autor:
Jugurtha Ouboudinar, Ramon Corpuz, Martin Leduc, Jean-Simon Duceppe, Alexandre Laverdure, Mikaël Tremblay, Kathy Hince, Amélie Blais, Marie-Pier Cloutier, Richard L. Hébert, Christopher R.J. Kennedy, Alexandra Blais, Liette Gervais, Lilianne Geerts, Lyne Gagnon, Pierre Laurin, Jean-Christophe Simard, Steven R. LaPlante, Sylvie Létourneau, Jean-Francois Thibodeau, François A. Leblond, Brigitte Grouix, Shaun D. Abbott, Boulos Zacharie, Alexandra Felton, Vanessa Marques Quintela, William Gagnon, François Sarra-Bournet
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Non-alcoholic Fatty Liver Disease (NAFLD) is the most common form of liver disease and is associated with metabolic dysregulation. Although G protein-coupled receptor 84 (GPR84) has been associated with inflammation, its role in metabolic regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7b27b3602799ec5543996bcf182aca
http://europepmc.org/articles/PMC7391726
http://europepmc.org/articles/PMC7391726
Autor:
Jean-Francois Thibodeau, Alexandre Laverdure, Kathy Hince, Richard L. Hébert, Alex Gutsol, William Gagnon, Martin Leduc, Eldjonai Kamto, Liette Gervais, Shaun D. Abbott, Christopher R.J. Kennedy, Francois A. Leblond, Jonathan Richard, Pierre Laurin, Chet E. Holterman, Alexandra Felton, Ming-Zhi Zhang, François Sarra-Bournet, Mikaël Tremblay, Jugurtha Ouboudinar, Lilianne Geerts, Christopher Penney, Lyne Gagnon, Jocelyn Dupuis, Jean-Christophe Simard, Jean-Simon Duceppe, Quang Trinh Nguyen, Marie-Pier Cloutier, Raymond C. Harris, Angelino Calderone, Brigitte Grouix, Boulos Zacharie, Sylvie Létourneau
Publikováno v:
The American Journal of Pathology. 188:1132-1148
Numerous clinical conditions can lead to organ fibrosis and functional failure. There is a great need for therapies that could effectively target pathophysiological pathways involved in fibrosis. GPR40 and GPR84 are G protein–coupled receptors with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7315d43b6a70e40dd65fdef9ae6ea14c
https://doi.org/10.1016/j.ajpath.2018.01.009
https://doi.org/10.1016/j.ajpath.2018.01.009
Autor:
Mikaël Tremblay, William Gagnon, Martin Leduc, Marie-Pier Cloutier, Lyne Gagnon, François A. Leblond, Brigitte Grouix, François Sarra-Bournet, Jean-Christophe Simard, Pierre Laurin, Kathy Hince, Sylvie Létourneau
Publikováno v:
Diabetes. 67
Introduction: PBI-4547 is a novel orally active compound that is being developed for potential clinical use in patients suffering from metabolic and inflammatory/fibrosis-related diseases. This study examined the effect of PBI-4547 in NOD mice, a mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6346ba959877b8d9652ca33144b17a5e
https://doi.org/10.2337/db18-1817-p
https://doi.org/10.2337/db18-1817-p
Autor:
Lyne, Gagnon, Martin, Leduc, Jean-Francois, Thibodeau, Ming-Zhi, Zhang, Brigitte, Grouix, Francois, Sarra-Bournet, William, Gagnon, Kathy, Hince, Mikaël, Tremblay, Lilianne, Geerts, Christopher R J, Kennedy, Richard L, Hébert, Alex, Gutsol, Chet E, Holterman, Eldjonai, Kamto, Liette, Gervais, Jugurtha, Ouboudinar, Jonathan, Richard, Alexandra, Felton, Alexandre, Laverdure, Jean-Christophe, Simard, Sylvie, Létourneau, Marie-Pier, Cloutier, Francois A, Leblond, Shaun D, Abbott, Christopher, Penney, Jean-Simon, Duceppe, Boulos, Zacharie, Jocelyn, Dupuis, Angelino, Calderone, Quang T, Nguyen, Raymond C, Harris, Pierre, Laurin
Publikováno v:
The American journal of pathology. 188(5)
Numerous clinical conditions can lead to organ fibrosis and functional failure. There is a great need for therapies that could effectively target pathophysiological pathways involved in fibrosis. GPR40 and GPR84 are G protein-coupled receptors with f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::198faeef411e2db55cc78141485d6aed
https://pubmed.ncbi.nlm.nih.gov/29454750
https://pubmed.ncbi.nlm.nih.gov/29454750
Autor:
Kathy Hince, François Sarra-Bournet, Brigitte Grouix, Mikaël Tremblay, Jugurtha Ouboudinar, Lyne Gagnon, Jean-Christophe Simard, Pierre Laurin, Alexandra Felton, Alexandra Blais, Lilianne Geerts
Publikováno v:
Journal of Hepatology. 70:e194
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5d4a7900b0e31c3313e0a12c5776de
https://doi.org/10.1016/s0618-8278(19)30359-7
https://doi.org/10.1016/s0618-8278(19)30359-7
Autor:
Marie-Pier Cloutier, Martin Leduc, Brigitte Grouix, Shaun D. Abbott, Mikaël Tremblay, Alexandre Laverdure, Kathy Hince, Boulos Zacharie, Lyne Gagnon, Lilianne Geerts, Jean-Simon Duceppe, François Sarra-Bournet, Liette Gervais, Pierre Laurin
Publikováno v:
QJM: An International Journal of Medicine.
PBI-4050 is a first-in-class orally active compound which displays antifibrotic activities in kidney, heart, liver, pancreas and lung models. PBI-4050 was found to be safe and well tolerated in healthy volunteers and in patients with CKD and Type 2 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cee2f7e94368020a407bddc12534078
https://doi.org/10.1093/qjmed/hcw120.027
https://doi.org/10.1093/qjmed/hcw120.027
Autor:
Jean-Simon Duceppe, Kathy Hince, Mikaël Tremblay, Shaun D. Abbott, Brigitte Grouix, François Sarra-Bournet, Boulos Zacharie, Alexandra Felton, Lyne Gagnon, Pierre Laurin
Publikováno v:
Journal of Hepatology. 68:S408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44ef90e5d89b99111e7e11d6cc1c8ff5
https://doi.org/10.1016/s0168-8278(18)31053-5
https://doi.org/10.1016/s0168-8278(18)31053-5
Autor:
Alexandra Felton, François Sarra-Bournet, B. Zacharie, Pierre Laurin, Brigitte Grouix, Mikaël Tremblay, Kathy Hince, J.-S. Duceppe, S. Abbott, Lyne Gagnon
Publikováno v:
Journal of Hepatology. 64:S228-S229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03c52210edbc6df86442c9bc3350761
https://doi.org/10.1016/s0168-8278(16)00211-7
https://doi.org/10.1016/s0168-8278(16)00211-7
Autor:
Martin Leduc, Alexandra Felton, Lyne Gagnon, François Sarra-Bournet, Brigitte Grouix, Marie-Pier Cloutier, Lilianne Geerts, Mikaël Tremblay, Liette Gervais, Kathy Hince, Pierre Laurin, Frank Cesari, John Moran, William Gagnon
Publikováno v:
Nephrology Dialysis Transplantation. 30:iii411-iii412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9023dcdf6f4483a5aa93ee4759c59b31
https://doi.org/10.1093/ndt/gfv188.65
https://doi.org/10.1093/ndt/gfv188.65
Autor:
Lyne Gagnon, William Gagnon, Lilianne Geerts, Alexandre Laverdure, Kathy Hince, Alexandra Felton, Liette Gervais, Pierre Laurin, François Sarra-Bournet, Brigitte Grouix, Martin Leduc
Publikováno v:
Nephrology Dialysis Transplantation. 31:i10-i10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5edd1d500203f7faf4cee7b66a84805a
https://doi.org/10.1093/ndt/gfw120.05
https://doi.org/10.1093/ndt/gfw120.05