Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathryne E. Marks"'
Autor:
Mehreen Elahee, Alisa A. Mueller, Runci Wang, Kathryne E. Marks, Takanori Sasaki, Ye Cao, Andrea Fava, Paul F. Dellaripa, Francesco Boin, Deepak A. Rao
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 7, Pp 429-439 (2024)
Objective T cells contribute to tissue injury in systemic sclerosis (SSc), yet the specific T cell subsets expanded in patients with SSc remain incompletely defined. Here we evaluated specific phenotypes and functions of peripheral helper T (Tph) and
Externí odkaz:
https://doaj.org/article/f28238a6fae84f978ff2cf2458dae924
Autor:
Kelly D. O’Neill, Kathryne E. Marks, Pamela S. Sinicrope, Cynthia S. Crowson, Dana Symons, Elena Myasoedova, John M. Davis III
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 12, Pp 870-878 (2021)
Objective Treat‐to‐target (T2T) and shared decision‐making are valued features of current guidelines for rheumatoid arthritis (RA) management. Although T2T has demonstrated value for improving RA outcomes, implementation remains inconsistent an
Externí odkaz:
https://doaj.org/article/be86d6cd45564e0c868957e078862159
Autor:
Kathryne E. Marks, Stephanie Flaherty, Kristen M. Patterson, Matthew Stratton, Gustavo J. Martinez, Joseph M. Reynolds
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109303- (2021)
Summary: Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular programming underlying Th17 cell pathogenicity remains insufficiently understood. Activation of Toll-like receptor 2 (TLR2) increases Th17 cell inflammatory po
Externí odkaz:
https://doaj.org/article/a5f54f934b404e2cae07baf4b2c9f85e
Autor:
Pamela S. Sinicrope, Cynthia S. Crowson, Kelly D. O’Neill, Elena Myasoedova, Kathryne E. Marks, John M. Davis, Dana Symons
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 12, Pp 870-878 (2021)
ACR Open Rheumatology
ACR Open Rheumatology
OBJECTIVE Treat-to-target (T2T) and shared decision-making are valued features of current guidelines for rheumatoid arthritis (RA) management. Although T2T has demonstrated value for improving RA outcomes, implementation remains inconsistent and lack
Autor:
Sara K. Tedeschi, Daniel H. Solomon, Yuezhou Chen, Jack Ellrodt, Mary Grace Whelan, Jacklyn Stratton, Keigo Hayashi, Noah Benjamin Whiteman, Lin Chen, Ifeoluwakiisi Adejoorin, Kathryne E. Marks, Emma Gomez-Rivas, Deepak A. Rao, A. Helena Jonsson, Duane R. Wesemann
Publikováno v:
Seminars in Arthritis and Rheumatism. 59:152177
Autor:
Garrett S. Dunlap, Karmela K Chan, Michael B. Brenner, Ole-Petter R. Hamnvik, A. Helena Jonsson, Aidan Tirpack, Lindsey A MacFarlane, Miriam R. Fein, Laura T. Donlin, Le Min, Edward F. DiCarlo, Susan M. Goodman, Deepak A. Rao, Anne R. Bass, Amy Cunningham-Bussel, Derrick J. Todd, Jeffrey A. Sparks, Lin Chen, Anvita Singaraju, Lorien Shakib, Kathryne E. Marks, Elena Massarotti, Runci Wang
Immune checkpoint inhibitor (ICI) therapies that promote T cell activation have improved outcomes for advanced malignancies yet also elicit harmful autoimmune reactions. The T cell mechanisms mediating these iatrogenic autoimmune events remain unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a481c205899cc132e94c194cf6d5d0
https://doi.org/10.1101/2021.10.19.464961
https://doi.org/10.1101/2021.10.19.464961
Publikováno v:
Immune Network
TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune response. In recent years it has become app
Autor:
Joseph M. Reynolds, Kathryne E. Marks, Stephanie Flaherty, Gustavo J. Martinez, Matthew Stratton
Publikováno v:
SSRN Electronic Journal.
Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular programming underlying Th17 cell pathogenicity remains insufficiently understood. Activation of toll-like receptor 2 (TLR2) increases Th17 cell inflammatory potential,
Autor:
Matthew Stratton, Kristen M. Patterson, Joseph M. Reynolds, Gustavo J. Martinez, Kathryne E. Marks, Stephanie Flaherty
Publikováno v:
Cell reports
Cell Reports, Vol 35, Iss 13, Pp 109303-(2021)
Cell Reports, Vol 35, Iss 13, Pp 109303-(2021)
SUMMARY Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular programming underlying Th17 cell pathogenicity remains insufficiently understood. Activation of Toll-like receptor 2 (TLR2) increases Th17 cell inflammatory pot
Publikováno v:
The Journal of Immunology. 204:142.23-142.23
CD4+ T cells, especially Th17 cells, are instrumental in the development and progression of autoimmune diseases, such as multiple sclerosis (MS), psoriasis, and rheumatoid arthritis. While pathogenic Th17 cells drive inflammation in autoimmunity, the