IL-6, TNF-α, and IL-10 levels/polymorphisms and their association with type 2 diabetes mellitus and obesity in Brazilian individuals

Autor: Kathryna Fontana Rodrigues, Nathalia Teixeira Pietrani, Adriana Aparecida Bosco, Fernanda Magalhães Freire Campos, Valéria Cristina Sandrim, Karina Braga Gomes

Publikováno v: Archives of Endocrinology and Metabolism, Vol 61, Iss 5, Pp 438-446 (2017)

ABSTRACT Objective This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10 levels and cytokine gene polymorphisms [TNF-α (-308 G→A), IL-6 (-174 C→G) and IL-10 (-1082 A→G, -819 T→C and -592 A→C)] in type 2 diabetes

Externí odkaz: https://doaj.org/article/f6992201b69749f3bd46ecee48854db8

Avaliação dos níveis de galectina-3 em pacientes com diabetes mellitus tipo 2 e doença renal crônica

Autor: Michelle Teodoro Alves, Nathalia T. Pietrani, Karina Braga Gomes, Isabella Dâmaris Passos de Souza, Kathryna Fontana Rodrigues, Adriana A. Bosco

Publikováno v: Jornal Brasileiro de Patologia e Medicina Laboratorial, Volume: 57, Article number: e2172021, Published: 12 FEB 2021
Jornal Brasileiro de Patologia e Medicina Laboratorial v.57 2021
Jornal Brasileiro de Patologia e Medicina Laboratorial
Sociedade Brasileira de Patologia (SBP)
instacron:SBP
Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 57 (2021)

INTRODUCTION: Type 2 diabetes mellitus (T2DM) is the most common manifestation of diabetes, accounting for about 90% of diagnosed cases. The causes of T2DM are not fully understood, but its pathogenesis is possibly associated with increased adiposity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cfb16e1aad98d7c91d622e820b35f3
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442021000100400&lng=en&tlng=en

Vitamin D receptor polymorphisms and the polycystic ovary syndrome: A systematic review

Autor: Michelle Teodoro Alves, Cláudia N. Ferreira, Karina Braga Gomes, Guilherme Victor Oliveira Pimenta dos Reis, Natália Alves Gontijo, Kathryna Fontana Rodrigues

Publikováno v: Journal of Obstetrics and Gynaecology Research. 43:436-446

Polycystic ovary syndrome (PCOS) is the most frequent endocrinological disorder that affects women of reproductive age, leading to metabolic alterations, such as hyperandrogenism, obesity, menstrual irregularities, insulin resistance, and polycystic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a728f281b0ed208893e333cbcf65439b
https://doi.org/10.1111/jog.13250

Circulating irisin is increased in type 2 diabetes mellitus and correlates with fasting glucose levels

Autor: Cláudia N. Ferreira, Karina Braga Gomes, Adriana A. Bosco, Nathalia T. Pietrani, Kathryna Fontana Rodrigues

Publikováno v: Apollo Medicine. 13:152-155

Background/aims Irisin is a hormone expressed in muscle, which is an exercise-induced myokine triggering browning of white adipose tissue and increases metabolic genes expression. Methods We investigated the irisin levels in 39 type 2 diabetes mellit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1dd9e0e5da346f5bf3dcefe1c2e387ed
https://doi.org/10.1016/j.apme.2016.02.010

Haptoglobin levels are influenced by Hp1-Hp2 polymorphism, obesity, inflammation, and hypertension in type 2 diabetes mellitus

Autor: Karina Braga Gomes, Adriana A. Bosco, Nathalia T. Pietrani, Valeria C. Sandrim, Kathryna Fontana Rodrigues, Laura M. L. Carvalho, Cláudia N. Ferreira

Publikováno v: Endocrinologia, diabetes y nutricion. 66(2)

Background Type 2 diabetes mellitus (T2DM) is an inflammatory condition associated to obesity and increased oxidative stress. Haptoglobin (Hp) is an acute phase reactant that scavenges extracorpuscular hemoglobin from circulation and prevents heme-ir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e3d072033e4dcf9c93de3931aa8572
https://pubmed.ncbi.nlm.nih.gov/30528492