Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kathryn V. Tormos"'
Autor:
Kurosh Ameri, Arman Jahangiri, Anthony M. Rajah, Kathryn V. Tormos, Ravi Nagarajan, Melike Pekmezci, Vien Nguyen, Matthew L. Wheeler, Michael P. Murphy, Timothy A. Sanders, Stefanie S. Jeffrey, Yerem Yeghiazarians, Paolo F. Rinaudo, Joseph F. Costello, Manish K. Aghi, Emin Maltepe
Publikováno v:
Cell Reports, Vol 10, Iss 6, Pp 891-899 (2015)
Hypoxia-inducible gene domain family member 1A (HIGD1A) is a survival factor induced by hypoxia-inducible factor 1 (HIF-1). HIF-1 regulates many responses to oxygen deprivation, but viable cells within hypoxic perinecrotic solid tumor regions frequen
Externí odkaz:
https://doaj.org/article/073f933d7346420aa940bda4e626e3d6
Autor:
Stephen M. Black, Emin Maltepe, Manuela Kellner, Gary W. Raff, Xutong Sun, Kathryn V. Tormos, Sanjeev A. Datar, Jeffrey R. Fineman, Jason Boehme, Wenhui Gong, Rebecca J Kameny, Jason X.-J. Yuan
Publikováno v:
Boehme, J; Sun, X; Tormos, KV; Gong, W; Kellner, M; Datar, SA; et al.(2016). Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation. American Journal of Physiology-Heart and Circulatory Physiology, 311(4), H944-H957. doi: 10.1152/ajpheart.00040.2016. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7zg1543m
© 2016 the American Physiological Society.Vascular cell hyperproliferation and metabolic reprogramming contribute to the pathophysiology of pulmonary arterial hypertension (PAH). An important cause of PAH in children with congenital heart disease (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa50b0e75c224d5d3b892a48752716dc
http://www.escholarship.org/uc/item/7zg1543m
http://www.escholarship.org/uc/item/7zg1543m
Autor:
Usha Warrior, Stephen W. Fesik, Michael R. Michaelides, Navdeep S. Chandel, Frank Weinberg, Jennifer B. Donnelly, Xiaoyu Lin, Kathryn V. Tormos, Caroline A. David, Yu Shen, Xiaoli Huang
Publikováno v:
Proceedings of the National Academy of Sciences. 105:174-179
Hypoxia-inducible factor-1 (HIF-1) plays an essential role in tumor development and progression by regulating genes that are vital for proliferation, glycolysis, angiogenesis, and metastasis. To identify strategies of targeting the HIF-1 pathway, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc82702e0af357ad938bc8aeacfcfde
https://doi.org/10.1073/pnas.0706585104
https://doi.org/10.1073/pnas.0706585104
Autor:
Timothy A. Sanders, Matthew L. Wheeler, Anthony M. Rajah, Ravi Nagarajan, Stefanie S. Jeffrey, Emin Maltepe, Michael P. Murphy, Paolo Rinaudo, Arman Jahangiri, Kathryn V. Tormos, Melike Pekmezci, Yerem Yeghiazarians, Joseph F. Costello, Manish K. Aghi, Kurosh Ameri, Vien Nguyen
Publikováno v:
Ameri, K; Jahangiri, A; Rajah, AM; Tormos, KV; Nagarajan, R; Pekmezci, M; et al.(2015). HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Reports, 10(6), 891-899. doi: 10.1016/j.celrep.2015.01.020. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5dg2z36c
Cell reports, vol 10, iss 6
Cell Reports, Vol 10, Iss 6, Pp 891-899 (2015)
Cell reports, vol 10, iss 6
Cell Reports, Vol 10, Iss 6, Pp 891-899 (2015)
© 2015 The Authors. Hypoxia-inducible gene domain family member 1A (HIGD1A) is a survival factor induced by hypoxia-inducible factor 1 (HIF-1). HIF-1 regulates many responses to oxygen deprivation, but viable cells within hypoxic perinecrotic solid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c706fbc6e721ea73ca49d9fc0ca4f4e7
https://pubmed.ncbi.nlm.nih.gov/25683712
https://pubmed.ncbi.nlm.nih.gov/25683712
Autor:
Ralph S. Marcucio, T. Miclau, Aaron Taylor, Ali Sadat, Chelsea S. Bahney, Kathryn V. Tormos, Emin Maltepe
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3409853830efd49165cb2abffae88b11
https://doi.org/10.1096/fasebj.28.1_supplement.342.6
https://doi.org/10.1096/fasebj.28.1_supplement.342.6
Autor:
Timothy A. Sanders, Hwa J. Choi, Stefanie S. Jeffrey, Michael DeLay, Kathryn V. Tormos, Kurosh Ameri, Paolo Rinaudo, Manish K. Aghi, Arman Jahangiri, Anthony M. Rajah, David H. Rowitch, Emin Maltepe, Matthew Donne, Vien Nguyen, Yerem Yeghiazarians
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62758 (2013)
PloS one, vol 8, iss 4
PLoS ONE
PloS one, vol 8, iss 4
PLoS ONE
Cellular stress responses are frequently governed by the subcellular localization of critical effector proteins. Apoptosis-inducing Factor (AIF) or Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH), for example, can translocate from mitochondria to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac248058c159c4216a2bc0e2d88e5a5
http://europepmc.org/articles/PMC3639984?pdf=render
http://europepmc.org/articles/PMC3639984?pdf=render
Publikováno v:
FEBS letters. 581(29)
The key transcription factor that regulates the cellular responses to hypoxia is hypoxia inducible factor-1 (HIF-1). The signaling mechanisms that regulate the hypoxic activation of HIF-1 are not fully understood. Our objective here was to test wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9830ee903b520a787d10aebfbddc9f3c
https://pubmed.ncbi.nlm.nih.gov/18036344
https://pubmed.ncbi.nlm.nih.gov/18036344
Autor:
Kathryn V. Tormos, LeeAnn Smith, Allison K. Wilson, Maryn Valdez, Maryka H. Bhattacharyya, Lina Agha
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a76e2859270ed53a63448524cb8e1be9
https://doi.org/10.1096/fasebj.20.5.lb17-c
https://doi.org/10.1096/fasebj.20.5.lb17-c
Autor:
Kathryn V. Tormos, Navdeep S. Chandel
Publikováno v:
Cell Metabolism. 14:720-721
Reactive oxygen species (ROS) dictate biological outcomes and are linked with myriad pathologies. However, measuring ROS in vivo remains a major obstacle in the field. Here, Albrecht et al. (2011) demonstrate the efficacy of redox-sensitive GFP in me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5359f7fa3151781a05ad537176696999
https://doi.org/10.1016/j.cmet.2011.11.008
https://doi.org/10.1016/j.cmet.2011.11.008
Autor:
Julissa Gonzalez, Kurosh Ameri, Xiaowei Liu, Emin Maltepe, Anthony M. Rajah, Timothy A. Sanders, Hwa J. Choi, Paolo Rinaudo, Kathryn V. Tormos, Diana M. Quinonez, Justin D. Tsai, Angela M. Park
Publikováno v:
PLoS ONE
Maltepe, Emin; Rinaudo, Paolo; Choi, HJ; Sanders, TA; Tormos, KV; Ameri, K; et al.(2013). ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1jk9d4gd
PLoS ONE, Vol 8, Iss 2, p e56949 (2013)
Maltepe, Emin; Rinaudo, Paolo; Choi, HJ; Sanders, TA; Tormos, KV; Ameri, K; et al.(2013). ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1jk9d4gd
PLoS ONE, Vol 8, Iss 2, p e56949 (2013)
The Hypoxia-inducible Factor (HIF) family of transcriptional regulators coordinates the expression of dozens of genes in response to oxygen deprivation. Mammalian development occurs in a hypoxic environment and HIF-null mice therefore die in utero du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba3301d6f868278d09d35742a79ddbc
https://doi.org/10.1371/journal.pone.0056949
https://doi.org/10.1371/journal.pone.0056949