Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Kathryn V, Papp"'
Autor:
Rory Boyle, Diana L. Townsend, Hannah M. Klinger, Catherine E. Scanlon, Ziwen Yuan, Gillian T. Coughlan, Mabel Seto, Zahra Shirzadi, Wai-Ying Wendy Yau, Roos J. Jutten, Christoph Schneider, Michelle E. Farrell, Bernard J. Hanseeuw, Elizabeth C. Mormino, Hyun-Sik Yang, Kathryn V. Papp, Rebecca E. Amariglio, Heidi I. L. Jacobs, Julie C. Price, Jasmeer P. Chhatwal, Aaron P. Schultz, Michael J. Properzi, Dorene M. Rentz, Keith A. Johnson, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Leveraging Alzheimer’s disease (AD) imaging biomarkers and longitudinal cognitive data may allow us to establish evidence of cognitive resilience (CR) to AD pathology in-vivo. Here, we applied latent class mixture modeling, adju
Externí odkaz:
https://doaj.org/article/533e6b89a4fd4deeb58b8bf4d29de93c
Autor:
Jennifer Pahl, Prokopis C. Prokopiou, Elisenda Bueichekú, Aaron P. Schultz, Kathryn V. Papp, Michelle E. Farrell, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I.L. Jacobs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Autopsy work reported that neuronal density in the locus coeruleus (LC) provides neural reserve against cognitive decline in dementia. Recent neuroimaging and pharmacological studies reported that left frontoparietal network funct
Externí odkaz:
https://doaj.org/article/78a9e2d37a8948558daa424d3e911cd8
Autor:
Mark A. Dubbelman, Ibai Diez, Christopher Gonzalez, Rebecca E. Amariglio, J. Alex Becker, Jasmeer P. Chhatwal, Jennifer R. Gatchel, Keith A. Johnson, Joseph J. Locascio, Onyinye J. Udeogu, Sharon Wang, Kathryn V. Papp, Michael J. Properzi, Dorene M. Rentz, Aaron P. Schultz, Reisa A. Sperling, Patrizia Vannini, Gad A. Marshall
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundChanges in everyday functioning constitute a clinically meaningful outcome, even in the early stages of Alzheimer's disease. Performance-based assessments of everyday functioning might help uncover these early changes. We aimed to investiga
Externí odkaz:
https://doaj.org/article/45aa0a5f9abd467ebe21cce9b62843f8
Autor:
Geoffroy Gagliardi, Elena Rodriguez-Vieitez, Victor Montal, Jorge Sepulcre, Ibai Diez, Cristina Lois, Bernard Hanseeuw, Aaron P. Schultz, Michael J. Properzi, Kathryn V. Papp, Gad A. Marshall, Juan Fortea, Keith A. Johnson, Reisa A. Sperling, Patrizia Vannini
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Introduction Non-invasive diffusion-weighted imaging (DWI) to assess brain microstructural changes via cortical mean diffusivity (cMD) has been shown to be cross-sectionally associated with tau in cognitively normal older adults, suggesting
Externí odkaz:
https://doaj.org/article/2f92c1fc8cc3460e9460c06eaf041613
Autor:
Mark A. Dubbelman, Tia C. Hall, Isabella M. Levesque, Kayden J. Mimmack, Sietske A. M. Sikkes, Shira H. Fischer, Dorene M. Rentz, Reisa A. Sperling, Kathryn V. Papp, Rebecca E. Amariglio, Gad A. Marshall
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION To investigate the utility of a new digital tool for measuring everyday functioning in preclinical Alzheimer's disease, we piloted the Assessment of Smartphone Everyday Tasks (ASSET) application. METHODS Forty‐six participants
Externí odkaz:
https://doaj.org/article/2016a0ed062f4fa0891b703d3ad9e856
Autor:
Prokopis C. Prokopiou, Nina Engels-Domínguez, Kathryn V. Papp, Matthew R. Scott, Aaron P. Schultz, Christoph Schneider, Michelle E. Farrell, Rachel F. Buckley, Yakeel T. Quiroz, Georges El Fakhri, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/064e0e4a05864dea8910777843fb04ad
Autor:
Christina B. Young, Elizabeth C. Mormino, Kathleen L. Poston, Keith A. Johnson, Dorene M. Rentz, Reisa A. Sperling, Kathryn V. Papp
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Scalable cognitive paradigms that provide metrics such as the Computerized Cognitive Composite (C3) may be sensitive enough to relate to Alzheimer's disease biomarkers in the preclinical clinically unimpaired (CU) stage. We examined CU older
Externí odkaz:
https://doaj.org/article/daa1b83c892e407bb6e6d084a5f8568d
Autor:
Fredrik Öhman, David Berron, Kathryn V. Papp, Silke Kern, Johan Skoog, Timothy Hadarsson Bodin, Anna Zettergren, Ingmar Skoog, Michael Schöll
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
BackgroundMobile app-based tools have the potential to yield rapid, cost-effective, and sensitive measures for detecting dementia-related cognitive impairment in clinical and research settings. At the same time, there is a substantial need to validat
Externí odkaz:
https://doaj.org/article/d09e616fa94f4fa2b32129ea88645f26
Autor:
Caroline Skirrow, Marton Meszaros, Udeepa Meepegama, Raphael Lenain, Kathryn V Papp, Jack Weston, Emil Fristed
Publikováno v:
JMIR Aging, Vol 5, Iss 3, p e37090 (2022)
BackgroundStory recall is a simple and sensitive cognitive test that is commonly used to measure changes in episodic memory function in early Alzheimer disease (AD). Recent advances in digital technology and natural language processing methods make t
Externí odkaz:
https://doaj.org/article/2907720129894251bf9d21602e99ec2f
Autor:
Mark A. Dubbelman, Roos J. Jutten, Sarah E. Tomaszewski Farias, Rebecca E. Amariglio, Rachel F. Buckley, Pieter Jelle Visser, Dorene M. Rentz, Keith A. Johnson, Michael J. Properzi, Aaron Schultz, Nancy Donovan, Jennifer R. Gatchell, Charlotte E. Teunissen, Bart N. M. Van Berckel, Wiesje M. Van der Flier, Reisa A. Sperling, Kathryn V. Papp, Philip Scheltens, Gad A. Marshall, Sietske A. M. Sikkes, for the Alzheimer Disease Neuroimaging Initiative, National Alzheimer’s Coordinating Center, the Harvard Aging Brain Study, the Alzheimer Dementia Cohort
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Impairment in daily functioning is a clinical hallmark of dementia. Difficulties with “instrumental activities of daily living” (IADL) seem to increase gradually over the course of Alzheimer’s disease (AD), before dementia o
Externí odkaz:
https://doaj.org/article/89c52c5343444b7788cbea71dd84912f