Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathryn Trewhitt"'
Autor:
Christopher B. Cole, Maria Pia Morelli, Massimo Fantini, Markku Miettinen, Patricia Fetsch, Cody Peer, William D. Figg, Tyler Yin, Nicole Houston, Ann McCoy, Stanley Lipkowitz, Alexandra Zimmer, Jung-min Lee, Miroslava Pavelova, Erin N. Villanueva, Kathryn Trewhitt, B. Brooke Solarz, Maria Fergusson, Sharon A. Mavroukakis, Anjum Zaki, Kwong Y. Tsang, Philip M. Arlen, Christina M. Annunziata
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background NEO201 is a humanized IgG1 monoclonal antibody (mAb) generated against tumor-associated antigens from patients with colorectal cancer. NEO-201 binds to core 1 or extended core 1 O-glycans expressed by its target cells. Here, we pr
Externí odkaz:
https://doaj.org/article/156401e08d7b44f9b984a38a26842574
Autor:
Christopher B. Cole, Maria Pia Morelli, Massimo Fantini, Markku Miettinen, Patricia Fetsch, Cody Peer, William D. Figg, Tyler Yin, Nicole Houston, Ann McCoy, Stanley Lipkowitz, Alexandra Zimmer, Jung-min Lee, Miroslava Pavelova, Erin N. Villanueva, Kathryn Trewhitt, B. Brooke Solarz, Maria Fergusson, Sharon A. Mavroukakis, Anjum Zaki, Kwong Y. Tsang, Philip M. Arlen, Christina M. Annunziata
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/e0d1020045bf414299bb74825342f029
Autor:
Christina M. Annunziata, Christopher B. Cole, Kathryn C. Zoon, Ana T. Nunes, Lindsey B. Rosen, Steven M. Holland, Soumya Korrapati, Chauha Pham, JoLynn Procter, Sandhya Panch, Naoza Collins-Johnson, David F. Stroncek, Steven L. Highfill, Yovanni Casablanca, Andrew Blakely, Leslie Smith, Erin N. Villanueva, Miroslava Pavelova, Alexandra Zimmer, Stanley Lipkowitz, Jung-min Lee, Nicole Houston, Ann McCoy, Irene Ekwede, Kathryn Trewhitt, Timothy G. Myers, Anna Duemler, Franklin Ning, Daniel S. Green
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2feab5077d48472041562350e1b5e877
https://doi.org/10.1158/1078-0432.22488489.v1
https://doi.org/10.1158/1078-0432.22488489.v1
Autor:
Christina M. Annunziata, Christopher B. Cole, Kathryn C. Zoon, Ana T. Nunes, Lindsey B. Rosen, Steven M. Holland, Soumya Korrapati, Chauha Pham, JoLynn Procter, Sandhya Panch, Naoza Collins-Johnson, David F. Stroncek, Steven L. Highfill, Yovanni Casablanca, Andrew Blakely, Leslie Smith, Erin N. Villanueva, Miroslava Pavelova, Alexandra Zimmer, Stanley Lipkowitz, Jung-min Lee, Nicole Houston, Ann McCoy, Irene Ekwede, Kathryn Trewhitt, Timothy G. Myers, Anna Duemler, Franklin Ning, Daniel S. Green
Purpose:Ovarian cancer is the most lethal gynecologic cancer and intrinsically resistant to checkpoint immunotherapies. We sought to augment innate immunity, building on previous work with IFNs and monocytes.Patients and Methods:Preclinical experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5d6f3d1a19ff96c8ac9b3ce92c531b
https://doi.org/10.1158/1078-0432.c.6532740.v1
https://doi.org/10.1158/1078-0432.c.6532740.v1
Autor:
Daniel S. Green, Franklin Ning, Anna Duemler, Timothy G. Myers, Kathryn Trewhitt, Irene Ekwede, Ann McCoy, Nicole Houston, Jung-min Lee, Stanley Lipkowitz, Alexandra Zimmer, Miroslava Pavelova, Erin N. Villanueva, Leslie Smith, Andrew Blakely, Yovanni Casablanca, Steven L. Highfill, David F. Stroncek, Naoza Collins-Johnson, Sandhya Panch, JoLynn Procter, Chauha Pham, Soumya Korrapati, Steven M. Holland, Lindsey B. Rosen, Ana T. Nunes, Kathryn C. Zoon, Christopher B. Cole, Christina M. Annunziata
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Purpose: Ovarian cancer is the most lethal gynecologic cancer and intrinsically resistant to checkpoint immunotherapies. We sought to augment innate immunity, building on previous work with IFNs and monocytes. Patients and Methods: Preclinical experi
Autor:
Erika J. Lampert, Elise C. Kohn, Alexandra S Zimmer, Kathryn Trewhitt, Christina M. Annunziata, Ann McCoy, Stanley Lipkowitz, Jung-Min Lee, Daniel An
Publikováno v:
Journal of Clinical Oncology. 38:6038-6038
6038 Background: Preclinical data suggest cell cycle checkpoint inhibition induces greater cell death in BRCA mutant HGSOC by causing replication stress and dysregulation of DNA damage responses. We hypothesized that prexasertib, a cell cycle checkpo
Autor:
Massimo Fantini, Jung-Min Lee, Philip M. Arlen, Kathryn Trewhitt, Stanley Lipkowitz, M. Pia Morelli, Nicole D. Houston, Christina M. Annunziata, Alexandra S Zimmer, Kwong Y. Tsang
Publikováno v:
Journal of Clinical Oncology. 38:e15002-e15002
e15002 Background: NEO-201 is a humanized IgG1 mAb that targets tumor-associated variants of CEACAM-5/6. NEO201 exerts anti-tumor activity by (NK)-mediated ADCC, CDC, and by enhancing NK cell cytotoxicity through blockade of CEACAM5-CEACAM1 interacti