Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kathryn Song Eng Cheah"'
Autor:
Zezhuo Su, Joshua Wing Kei Ho, Raymond Ching Hing Yau, Ying Lee Lam, Tony Wai Hung Shek, Maximus Chun Fai Yeung, Hongtai Chen, Richard O. C. Oreffo, Kathryn Song Eng Cheah, Kelvin Sin Chi Cheung
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The transformation of benign lesions to malignant tumours is a crucial aspect of understanding chondrosarcomas, which are malignant cartilage tumours that could develop from benign chondroid lesions. However, the process of malignant transfo
Externí odkaz:
https://doaj.org/article/2029ec6ada1b4795b6b1df671d5daa6e
Autor:
Tsz Long Chu, Peikai Chen, Anna Xiaodan Yu, Mingpeng Kong, Zhijia Tan, Kwok Yeung Tsang, Zhongjun Zhou, Kathryn Song Eng Cheah
Publikováno v:
eLife, Vol 12 (2023)
Bone homeostasis is regulated by hormones such as parathyroid hormone (PTH). While PTH can stimulate osteo-progenitor expansion and bone synthesis, how the PTH-signaling intensity in progenitors is controlled is unclear. Endochondral bone osteoblasts
Externí odkaz:
https://doaj.org/article/8263d27eb26f4eaca011192e0d5436a5
Autor:
Jason T Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J Mirando, Tuyet Nguyen, Wendi Guo, Deepika Sharma, Douglas Rouse, Colleen Wu, Kathryn Song Eng Cheah, Courtney M Karner, Matthew J Hilton
Publikováno v:
eLife, Vol 11 (2022)
Hypertrophic chondrocytes give rise to osteoblasts during skeletal development; however, the process by which these non-mitotic cells make this transition is not well understood. Prior studies have also suggested that skeletal stem and progenitor cel
Externí odkaz:
https://doaj.org/article/e5000bdddb6c48f5925edceea43da35c
Autor:
Vivian Tam, Peikai Chen, Anita Yee, Nestor Solis, Theo Klein, Mateusz Kudelko, Rakesh Sharma, Wilson CW Chan, Christopher M Overall, Lisbet Haglund, Pak C Sham, Kathryn Song Eng Cheah, Danny Chan
Publikováno v:
eLife, Vol 9 (2020)
The spatiotemporal proteome of the intervertebral disc (IVD) underpins its integrity and function. We present DIPPER, a deep and comprehensive IVD proteomic resource comprising 94 genome-wide profiles from 17 individuals. To begin with, protein modul
Externí odkaz:
https://doaj.org/article/c596cd9ca49d47fda9a6b3948db184da
Autor:
Cheng Wang, Zhijia Tan, Ben Niu, Kwok Yeung Tsang, Andrew Tai, Wilson C W Chan, Rebecca L K Lo, Keith K H Leung, Nelson W F Dung, Nobuyuki Itoh, Michael Q Zhang, Danny Chan, Kathryn Song Eng Cheah
Publikováno v:
eLife, Vol 7 (2018)
The integrated stress response (ISR) is activated by diverse forms of cellular stress, including endoplasmic reticulum (ER) stress, and is associated with diseases. However, the molecular mechanism(s) whereby the ISR impacts on differentiation is inc
Externí odkaz:
https://doaj.org/article/e9b7f79bdb4947d79e76d3b800866557
Autor:
Huanbo Wang, Chao Zheng, Weiguang Lu, Ting He, Jing Fan, Cheng Wang, Qiang Jie, Danny Chan, Kathryn Song Eng Cheah, Liu Yang
Publikováno v:
Matrix Biology. 110:76-90
Although recent lineage studies strongly support a chondrocyte-to-osteoblast differentiation continuum, the biological significance and molecular basis remain undetermined. In silico analysis at a single-cell level indicates a transient shutdown of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e45f8e617cfea62d706a37dfbf88d1
https://doi.org/10.1016/j.matbio.2022.04.006
https://doi.org/10.1016/j.matbio.2022.04.006
Autor:
Jason T. Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J. Mirando, Tuyet Nguyen, Wendi Guo, Deepika Sharma, Douglas Rouse, Colleen Wu, Kathryn Song Eng Cheah, Courtney M. Karner, Matthew J. Hilton
Hypertrophic chondrocytes give rise to osteoblasts during skeletal development; however, the process by which these non-mitotic cells make this transition is not well understood. Prior studies have also suggested that skeletal stem and progenitor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9596c484d94f9518a2a54f3c32e8a497
https://doi.org/10.1101/2021.05.18.444731
https://doi.org/10.1101/2021.05.18.444731
Autor:
Xueya Zhou, Ching-Lung Cheung, Tatsuki Karasugi, Jaro Karppinen, Dino Samartzis, Yi-Hsiang Hsu, Timothy Shin-Heng Mak, You-Qiang Song, Kazuhiro Chiba, Yoshiharu Kawaguchi, Yan Li, Danny Chan, Kenneth Man-Chee Cheung, Shiro Ikegawa, Kathryn Song-Eng Cheah, Pak Chung Sham
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics
Frontiers in Genetics
Lumbar disc degeneration (LDD) is age-related break-down in the fibrocartilaginous joints between lumbar vertebrae. It is a major cause of low back pain and is conventionally assessed by magnetic resonance imaging (MRI). Like most other complex trait
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf03f7c5341e4c1e14477bc805a8767