Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathryn Scholl"'
Autor:
Matthew J. Camiolo, Xiaoying Zhou, Timothy B. Oriss, Qi Yan, Michael Gorry, William Horne, John B. Trudeau, Kathryn Scholl, Wei Chen, Jay K. Kolls, Prabir Ray, Florian J. Weisel, Nadine M. Weisel, Nima Aghaeepour, Kari Nadeau, Sally E. Wenzel, Anuradha Ray
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108974- (2021)
Summary: Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-r
Externí odkaz:
https://doaj.org/article/c9fa672d9c7c4ce5951873f34b1a1ccf
Autor:
Sagar Laxman Kale, Sally E. Wenzel, Anuradha Ray, Kathryn Scholl, Marc Gauthier, T.B. Oriss, Prabir Ray
Publikováno v:
A21. AIRWAY IMMUNOLOGY.
Autor:
Sally E. Wenzel, Qi Yan, Florian Weisel, Matthew J. Camiolo, Xiaoying Zhou, Nadine M. Weisel, Timothy B. Oriss, Nima Aghaeepour, Kathryn Scholl, Jay K. Kolls, John B. Trudeau, Wei Chen, Kari C. Nadeau, William Horne, Anuradha Ray, Prabir Ray, Michael C. Gorry
Publikováno v:
Cell reports
Cell Reports, Vol 35, Iss 2, Pp 108974-(2021)
Cell Reports, Vol 35, Iss 2, Pp 108974-(2021)
SUMMARY Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-re
Autor:
Sally E. Wenzel, Marc Gauthier, Huijuan Yuan, Sudipta Das, Sagar Laxman Kale, Matthew J. Camiolo, Timothy B. Oriss, Sanmei Hu, Jie Chen, Anuradha Ray, Prabir Ray, Kathryn Scholl
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Many severe asthma (SA) patients fail to respond to Type 2 inflammation targeted therapies. We previously identified a cohort of SA subjects expressing Type 1 inflammation manifesting with IFN-γ expression with variable Type 2 responses.
Autor:
Seyed Mehdi Nouraie, Rachel Hannum, Christina Morse, Rachael Huff, Timothy B. Oriss, Sally E. Wenzel, Marc Gauthier, Krishnendu Chakraborty, Kathryn Scholl, Mahesh Raundhal, Sudipta Das, Anuradha Ray, Prabir Ray
Publikováno v:
JCI Insight. 2
Severe asthma (SA) is a significant problem both clinically and economically, given its poor response to corticosteroids (CS). We recently reported a complex type 1-dominated (IFN-γ-dominated) immune response in more than 50% of severe asthmatics de