Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kathryn S. Wilson"'
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension (PH) is a disease associated with vasoconstriction and remodelling of the pulmonary vasculature. Pulmonary artery fibroblasts (PAFs) play an important role in hypoxic-induced remodelling. Connexin 43 (Cx43) is involved in cellu
Externí odkaz:
https://doaj.org/article/59ba0b8e790446f59b541bcc24ffbc8e
Autor:
Kathryn S. Wilson, Hanna Buist, Kornelija Suveizdyte, John T. Liles, Grant R. Budas, Colin Hughes, Margaret R. MacLean, Martin Johnson, Alistair C. Church, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinas
Externí odkaz:
https://doaj.org/article/6525394d6a864924aa813898fecdb00f
Autor:
Geeshath Jayasekera, Kathryn S. Wilson, Hanna Buist, Rosemary Woodward, Aysel Uckan, Colin Hughes, Margaret Nilsen, A Colin Church, Martin K. Johnson, Lindsay Gallagher, James Mullin, Mandy R. MacLean, William M. Holmes, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological feature
Externí odkaz:
https://doaj.org/article/16df05497cb345c3b63ec397451bbf19
Autor:
Hanna Buist, Margaret Nilsen, Kathryn S. Wilson, Geeshath Jayasekera, A Colin Church, David J Welsh, Rosemary Woodward, Martin K Johnson, Lindsay Gallagher, Andrew J Peacock, Colin Hughes, Jim Mullin, William M. Holmes, Mandy MacLean, Aysel Uckan
Publikováno v:
Pulmonary Circulation
Pulmonary Circulation, Vol 10 (2020)
Pulmonary Circulation, Vol 10 (2020)
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological feature
Autor:
Andrew J. Peacock, Kathryn S. Wilson, Kornelija Suveizdyte, Grant R. Budas, Margaret R. MacLean, David J. Welsh, John T. Liles, Alistair C. Church, Hanna Buist, Martin Johnson, Colin Hughes
Publikováno v:
Pulmonary Circulation
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinas
Autor:
Grant R. Budas, John T. Liles, Colin Church, Andrew J. Peacock, Kathryn S. Wilson, Seth Fairfax, Geeshath Jayasekera, Colin Hughes, Mandy MacLean, Hanna Buist, Margaret Nilsen, David J. Welsh
Publikováno v:
Pulmonary Circulation and Pulmonary Vascular Disease.
Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) involves remodelling of the pulmonary arteries, increased pulmonary vascular resistance (PVR) and right ventricular (RV) dysfunction. Apoptosis Signal-regulating Kinase-1 (ASK1) is
Autor:
David A. Welsh, Kathryn S. Wilson, Margaret Nilsen, William M. Holmes, Andrew J. Peacock, Mandy MacLean, Hanna Buist, Colin Hughes, Lindsay Gallagher, Colin Church, Geeshath Jayasekera, Jim Mullin
Publikováno v:
Pulmonary Circulation and Pulmonary Vascular Disease.
Background: SUGEN/hypoxia (SuHx) causes pulmonary hypertension (PH) in rats. Cardiac MR (CMR) is the gold standard for determining ventricular mass, volume and function. We hypothesised that CMR could be used to measure progressive RV changes in the
Autor:
Emad A S Al-Dujaili, Kathryn S. Wilson, Gianfranco Matrone, Carl S. Tucker, Dawn E W Livingstone, Christopher J. Kenyon, John J. Mullins, Martin A. Denvir, Patrick W. F. Hadoke
Publikováno v:
The Journal of Physiology. 591:6209-6220
While glucocorticoids (GCs) are known to be present in the zebrafish embryo, little is known about their physiological roles at this stage. We hypothesised that GCs play key roles in stress response, hatching and swim activity during early developmen
Autor:
Carl S. Tucker, James Baily, Kathryn S. Wilson, John M. Girkin, John J. Mullins, Martin A. Denvir, Jonathan M. Taylor, Gianfranco Matrone, Gordon D. Love
Publikováno v:
International journal of cardiology, 2013, Vol.168(4), pp.3913-3919 [Peer Reviewed Journal]
Matrone, G, Taylor, J M, Wilson, K S, Baily, J, Love, G D, Girkin, J M, Mullins, J J, Tucker, C S & Denvir, M A 2013, ' Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair ', International Journal of Cardiology, vol. 168, no. 4, pp. 3913-9 . https://doi.org/10.1016/j.ijcard.2013.06.063
International Journal of Cardiology
Matrone, G, Taylor, J M, Wilson, K S, Baily, J, Love, G D, Girkin, J M, Mullins, J J, Tucker, C S & Denvir, M A 2013, ' Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair ', International Journal of Cardiology, vol. 168, no. 4, pp. 3913-9 . https://doi.org/10.1016/j.ijcard.2013.06.063
International Journal of Cardiology
Background:\ud While the adult zebrafish (Danio rerio) heart demonstrates a remarkable capacity for self-renewal following apical resection little is known about the response to injury in the embryonic heart.\ud \ud Methods:\ud Injury to the beating
Autor:
Korneilija Suveizdyte, Kathryn S. Wilson, John T. Liles, Grant R. Budas, David J. Welsh, Andrew J. Peacock
Publikováno v:
4.3 Pulmonary Circulation and Pulmonary Vascular Diseases.
Rationale: Pulmonary hypertension involves progressive remodelling of the pulmonary arteries. ASK1 is an apical MAPK, which undergoes activation in response to oxidative stress, resulting in activation of p38 MAPK. Here, we investigated the role of A