Výsledky vyhledávání - "Kathryn S. McKee"

A cytokine and angiogenic factor (CAF) analysis in plasma for selection of sorafenib therapy in patients with metastatic renal cell carcinoma

Autor: Mehrdad Khajavi, John V. Heymach, Amado J. Zurita, Christopher J. Logothetis, Hai T. Tran, Kathryn S. McKee, Nizar M. Tannir, Matthew H. Herynk, D. Z. Du, Lei Xu, Shaoyu Yan, Eric Jonasch, X. Wang

Publikováno v: Annals of Oncology. 23:46-52

Background: We investigated cytokines and angiogenic factors (CAFs) in patients with metastatic renal cell carcinoma (mRCC) treated in a randomized phase II clinical trial of sorafenib versus sorafenib+ interferon-a (IFN-a) that yielded no difference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96bb93d5450f38d41a894a7c6021463
https://doi.org/10.1093/annonc/mdr047

Zobrazit plný text záznamu

CD26 Regulates p38 Mitogen-Activated Protein Kinase–Dependent Phosphorylation of Integrin β1, Adhesion to Extracellular Matrix, and Tumorigenicity of T-Anaplastic Large Cell Lymphoma Karpas 299

Autor: Toshiko Yamochi, Chikao Morimoto, Ugur Aytac, Kathryn S. McKee, Tadanori Yamochi, Tsutomu Sato, Nam H. Dang, Kei Ohnuma

Publikováno v: Cancer Research. 65:6950-6956

CD26 is an antigen with key role in T-cell biology and is expressed on selected subsets of aggressive T-cell malignancies. To elucidate the role of CD26 in tumor behavior, we examine the effect of CD26 depletion by small interfering RNA transfection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324bfb2e78b7153b14cdb650c04ea27c
https://doi.org/10.1158/0008-5472.can-05-0647

Zobrazit plný text záznamu

Regulation of p38 Phosphorylation and Topoisomerase IIα Expression in the B-Cell Lymphoma Line Jiyoye by CD26/Dipeptidyl Peptidase IV Is Associated with EnhancedIn vitroandIn vivoSensitivity to Doxorubicin

Autor: Kazuya Sato, Nam H. Dang, Kei Ohnuma, Toshiko Yamochi, Kathryn S. McKee, Chikao Morimoto, Tadanori Yamochi, Ugur Aytac, Tsutomu Sato

Publikováno v: Cancer Research. 65:1973-1983

CD26 is a Mr 110,000 surface-bound glycoprotein with diverse functional properties, including having a key role in normal T-cell physiology and the development of certain cancers. In this article, we show that surface expression of CD26, especially i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f39822ea4580db78d12d1372115c39
https://doi.org/10.1158/0008-5472.can-04-2611

Zobrazit plný text záznamu

Iron Is Not Required in the Lactoferrin Stimulation of Thymidine Incorporation into the DNA of Rat Crypt Enterocytes

Autor: Kathryn S Mckee, H. A. Huebers, Buford L. Nichols

Publikováno v: Pediatric Research. 27:525-528

Lactoferrin has been identified as a factor in human colostrum that accounts for increased incorporation of thymidine into the DNA in an in vitro rat crypt enterocyte bioassay. We have examined lacatoferrin-stimulated thymidine incorporation by compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7066e297c6efe473aacb59a3a3ce87
https://doi.org/10.1203/00006450-199005000-00022

Zobrazit plný text záznamu

Plasma cytokines and angiogenic factors (CAFs) for evaluation of risk of recurrence and classification of patients (pts) with nonmetastatic renal cell carcinoma (RCC)

Autor: John V. Heymach, Surena F. Matin, Eric Jonasch, Hai T. Tran, Xuemei Wang, Mehrdad Khajavi, Christopher G. Wood, Amado J. Zurita, Stefania Fiorentino, Kathryn S. McKee

Publikováno v: Web of Science

e15075 Background: Although recent years have brought great progress into understanding the pathogenesis of RCC and multiple promising biomarkers, no tumor tissue or blood-based test has yet been established to assist in the clinical determination of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e55681553c109360bcc359fcb0cc2c7
https://doi.org/10.1200/jco.2012.30.15_suppl.e15075

Zobrazit plný text záznamu

Plasma cytokines and angiogenic factors (CAFs) associated with risk of recurrence and tumor dependence in patients (pts) with nonmetastatic renal cell carcinoma (RCC)

Autor: Stefania Fiorentino, Surena F. Matin, Amado J. Zurita, Xuemei Wang, John V. Heymach, Hai T. Tran, Mehrdad Khajavi, Christopher G. Wood, Eric Jonasch, Kathryn S. McKee

Publikováno v: Journal of Clinical Oncology. 30:383-383

383 Background: Although recent years have brought great progress into understanding the pathogenesis of RCC and multiple promising biomarkers, no tumor tissue or blood-based test has yet been validated for clinical use. The main objectives of this e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1f6b77a9011fe88cc321b5ac0223cf9
https://doi.org/10.1200/jco.2012.30.5_suppl.383

Zobrazit plný text záznamu

Cytokine and angiogenic factor (CAF) profiling for identification of markers associated with response to cediranib in metastatic renal cell carcinoma (mRCC)

Autor: Mehrdad Khajavi, John V. Heymach, Shaoyu Yan, Hai T. Tran, Peter F.A. Mulders, Amado J. Zurita, Bijoyesh Mookerjee, Laura Pike, Juliane M. Jürgensmeier, Kathryn S. McKee

Publikováno v: Journal of Clinical Oncology. 29:362-362

362 Background: Cediranib is a highly potent and selective signaling inhibitor of vascular endothelial growth factor (VEGF) receptors−1, −2, −3 and c-Kit. In a phase II trial, patients (pts) with mRCC were randomized 3:1 to treatment with cedir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49972f69d988511b70ed2509e839b4c4
https://doi.org/10.1200/jco.2011.29.7_suppl.362

Zobrazit plný text záznamu

A cytokine and angiogenic factor (CAF) plasma signature for selection of sorafenib (SR) therapy in patients (pts) with metastatic renal cell carcinoma (mRCC)

Autor: D. Z. Du, Lei Xu, Eric Jonasch, Nizar M. Tannir, X. Wang, Amado J. Zurita, Kathryn S. McKee, Matthew H. Herynk, Shaoyu Yan, John V. Heymach, Hai T. Tran

Publikováno v: Journal of Clinical Oncology. 27:5114-5114

5114 Background: SR, an oral inhibitor of Raf kinase, RET-receptor (R), VEGFR-1, 2, and 3, PDGFR-β, FLT-3, and c-KIT tyrosine kinases, has been shown to prolong progression-free survival (PFS) in mRCC after cytokine failure. In a phase II trial, mRC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eecb41816dcc5964a9773cc2cbc5c89a
https://doi.org/10.1200/jco.2009.27.15_suppl.5114

Zobrazit plný text záznamu

Cediranib targeting of circulating VEGFR-1+ monocyte subpopulations

Autor: J. Drevs, Kathryn S. McKee, John V. Heymach, Thomas A. Puchalski, Amado J. Zurita, Jane Robertson, Hua-Kang Wu, Ute Zirrgiebel, Juliane M. Jürgensmeier

Publikováno v: Journal of Clinical Oncology. 26:14687-14687

14687 Background: Recent studies suggest that specific subpopulations of monocytes and myeloid progenitors, particularly those expressing VEGFR-1, play a key role in promoting tumor angiogenesis an...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::788a899608e4067e771cdac42705688a
https://doi.org/10.1200/jco.2008.26.15_suppl.14687

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání