The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: a systematic review

Autor: Quinten Debrabander, Kathryn S. Hensley, Christina K. Psomas, Wichor Bramer, Tokameh Mahmoudi, Berend J. van Welzen, Annelies Verbon, Casper Rokx

Publikováno v: Journal of Virus Eradication, Vol 9, Iss 3, Pp 100342- (2023)

Introduction: Understanding the clinical potency of latency-reversing agents (LRAs) on the HIV-1 reservoir is useful to deploy future strategies. This systematic review evaluated the effects of LRAs in human intervention studies. Methods: A literatur

Externí odkaz: https://doaj.org/article/e46f04a2fd734824a345ee2831a5a94a

Immunogenicity of an Additional mRNA-1273 SARS-CoV-2 Vaccination in People With HIV With Hyporesponse After Primary Vaccination

Autor: Marlou J Jongkees, Daryl Geers, Kathryn S Hensley, Wesley Huisman, Corine H GeurtsvanKessel, Susanne Bogers, Lennert Gommers, Grigorios Papageorgiou, Simon P Jochems, Jan G den Hollander, Emile F Schippers, Heidi S M Ammerlaan, Wouter F W Bierman, Marc van der Valk, Marvin A H Berrevoets, Robert Soetekouw, Nienke Langebeek, Anke H W Bruns, Eliane M S Leyten, Kim C E Sigaloff, Marit G A van Vonderen, Corine E Delsing, Judith Branger, Peter D Katsikis, Yvonne M Mueller, Rory D de Vries, Bart J A Rijnders, Kees Brinkman, Casper Rokx, Anna H E Roukens

Publikováno v: The Journal of Infectious Diseases, 227(5), 651-662. OXFORD UNIV PRESS INC
The Journal of Infectious Diseases, 227(5), 651-662. Oxford University Press
Jongkees, M J, Geers, D, Hensley, K S, Huisman, W, GeurtsvanKessel, C H, Bogers, S, Gommers, L, Papageorgiou, G, Jochems, S P, den Hollander, J G, Schippers, E F, Ammerlaan, H S M, Bierman, W F W, van der Valk, M, Berrevoets, M A H, Soetekouw, R, Langebeek, N, Bruns, A H W, Leyten, E M S, Sigaloff, K C E, van Vonderen, M G A, Delsing, C E, Branger, J, Katsikis, P D, Mueller, Y M, de Vries, R D, Rijnders, B J A, Brinkman, K, Rokx, C & Roukens, A H E 2023, ' Immunogenicity of an Additional mRNA-1273 SARS-CoV-2 Vaccination in People With HIV With Hyporesponse After Primary Vaccination ', The Journal of infectious diseases, vol. 227, no. 5, pp. 651-662 . https://doi.org/10.1093/infdis/jiac451
The Journal of infectious diseases, 227(5), 651-662. Oxford University Press

BackgroundThe COVIH study is a prospective coronavirus disease 2019 (COVID-19) vaccination study in 1154 people with HIV (PWH), of whom 14% showed reduced antibody levels after primary vaccination. We evaluated whether an additional vaccination boost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212f4cb5bd26595f95b402b24185a8e9
https://doi.org/10.1093/infdis/jiac451

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Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV: a nationwide prospective cohort study in the Netherlands

Autor: Kathryn S. Hensley, Marlou J. Jongkees, Daryl Geers, Corine H. GeurtsvanKessel, Yvonne M. Mueller, Virgil A.S.H. Dalm, Grigorios Papageorgiou, Hanka Steggink, Alicja Gorska, Susanne Bogers, Jan G. den Hollander, Wouter F.W. Bierman, Luc B.S. Gelinck, Emile F. Schippers, Heidi S.M. Ammerlaan, Marc van der Valk, Marit G.A. van Vonderen, Corine E. Delsing, Elisabeth H. Gisolf, Anke H.W. Bruns, Fanny N. Lauw, Marvin A.H. Berrevoets, Kim C.E. Sigaloff, Robert Soetekouw, Judith Branger, Quirijn de Mast, Adriana J.J. Lammers, Selwyn H. Lowe, Rory D. de Vries, Peter D. Katsikis, Bart J.A. Rijnders, Kees Brinkman, Anna H.E. Roukens, Casper Rokx

BackgroundVaccines can be less immunogenic in people living with HIV (PLWH), but for SARS-CoV-2 vaccinations this is unknown.Methods and FindingsA prospective cohort study to examine the immunogenicity of BNT162b2, mRNA-1273, ChAdOx1-S and Ad26.COV2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7528a462db3586b8c9c52ddd2c7ee031
https://doi.org/10.1101/2022.03.31.22273221