Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kathryn S. E. Cheah"'
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-16 (2019)
Abstract Background The growth plate is a special region of the cartilage that drives longitudinal growth of long bones. Proliferating chondrocytes in the growth plate, arranged in columns, divide perpendicular to the long axis of the growth plate th
Externí odkaz:
https://doaj.org/article/f911a3f06d5947cfb56a432817d7739e
Autor:
Jessica Aijia Liu, Yanxia Rao, May Pui Lai Cheung, Man-Ning Hui, Ming-Hoi Wu, Lo-Kong Chan, Irene Oi-Lin Ng, Ben Niu, Kathryn S. E. Cheah, Rakesh Sharma, Louis Hodgson, Martin Cheung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Following epithelial-mesenchymal transition, avian trunk neural crest cell polarity determines directional migration but how this is established is unclear. Here, the authors find that the RhoGAP, Deleted in liver cancer 1, is asymmetrically localize
Externí odkaz:
https://doaj.org/article/d5afe614c7da4570bdef1328892dfbb0
Autor:
Yinxiang Wang, Jessica Aijia Liu, Keith K. H. Leung, Mai Har Sham, Danny Chan, Kathryn S. E. Cheah, Martin Cheung
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Previous studies have demonstrated the ability of reprogramming endochondral bone into induced pluripotent stem (iPS) cells, but whether similar phenomenon occurs in intramembranous bone remains to be determined. Here we adopted fluorescence-activate
Externí odkaz:
https://doaj.org/article/0710d492b9114c74aeb813b278b0addc
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008254 (2019)
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation. Fibroblast Growth
Externí odkaz:
https://doaj.org/article/244c740174984953b431dc71bc1b4076
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211333 (2019)
Excessive Hedgehog (Hh) signaling in chondrocytes is sufficient to cause formation of enchondroma-like lesions which can progress to chondrosarcoma. To elucidate potential underlying mechanisms, we identified GLI1 and GLI2 target genes in human chond
Externí odkaz:
https://doaj.org/article/1fd536a070a047d581be312e1bc52bdf
Autor:
Irene Y. Y. Szeto, Daniel K. H. Chu, Peikai Chen, Ka Chi Chu, Tiffany Y. K. Au, Keith K. H. Leung, Yong-Heng Huang, Sarah L. Wynn, Angel C. Y. Mak, Ying-Shing Chan, Wood Yee Chan, Ralf Jauch, Bernd Fritzsch, Mai Har Sham, Robin Lovell-Badge, Kathryn S. E. Cheah
The in vivo mechanisms underlying dominant syndromes caused by mutations in SRY-Box Transcription Factor 9 ( SOX9 ) and SOX10 ( SOXE ) transcription factors, when they either are expressed alone or are coexpressed, are ill-defined. We created a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c45d1bc5271c620034d32213c78820
Publikováno v:
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 31(3)
Modic changes (MC) on magnetic resonance imaging (MRI) have been associated with the development and severity of low back pain (LBP). The etiology of MC remains elusive, but it has been suggested that altered metabolism may be a risk factor. As such,
Autor:
Ben Niu, Kathryn S. E. Cheah, Zhijia Tan, Danny Chan, Kwok Yeung Tsang, Mingpeng Kong, Songjia Wen, Chi-chung Hui, Christine Hartmann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5efb5833e46926808f9582b4013d84d
https://doi.org/10.1002/jbmr.4132/v2/response1
https://doi.org/10.1002/jbmr.4132/v2/response1
Autor:
Kwok Yeung Tsang, Danny Chan, Deborah Cheslett, Wilson C W Chan, Chi Leong So, Ian G Melhado, Tori W Y Chan, Kin Ming Kwan, Ernst B Hunziker, Yoshihiko Yamada, John F Bateman, Kenneth M C Cheung, Kathryn S E Cheah
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e44 (2007)
In protein folding and secretion disorders, activation of endoplasmic reticulum (ER) stress signaling (ERSS) protects cells, alleviating stress that would otherwise trigger apoptosis. Whether the stress-surviving cells resume normal function is not k
Externí odkaz:
https://doaj.org/article/0bf1411e2eaa41249074f01a653e8e5a
Publikováno v:
Current topics in developmental biology. 133
A complex cascade of highly regulated processes of cell fate determination, differentiation, proliferation and transdifferentiation dictate the patterning, morphogenesis and growth of the vertebrate skeleton, perturbation of which results in malforma