Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kathryn R. Spencer"'
Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release
Autor:
Anita Pottekat, Scott Becker, Kathryn R. Spencer, John R. Yates, III, Gerard Manning, Pamela Itkin-Ansari, William E. Balch
Publikováno v:
Cell Reports, Vol 4, Iss 5, Pp 921-930 (2013)
Insulin homeostasis in pancreatic β cells is now recognized as a critical element in the progression of obesity and type II diabetes (T2D). Proteins that interact with insulin to direct its sequential synthesis, folding, trafficking, and packaging i
Externí odkaz:
https://doaj.org/article/00e3f3761be044b295b2fca4466d8629
Autor:
Seth R Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Jessica X Du, Kathryn R Spencer, Andrea Hartzell, Carol Girgiss, Yusuf T Abaci, Yufeng Shao, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg, Giordano Lippi
Publikováno v:
eLife, Vol 12 (2023)
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of this program. Indeed, deletion of neuron-enriched miRNAs induces strong d
Externí odkaz:
https://doaj.org/article/b595d3de11dc4474b897975c00e26573