Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathryn R. Goodwin"'
Publikováno v:
Journal of Microcolumn Separations. 7:521-527
Transmissible spongiform encephalopathies of animals and humans are infectious diseases that cause progressive degenerative disorders of the central nervous system. These diseases are caused by an accumulation in the lysosymes of a modified normal ce
Publikováno v:
Journal of Chromatography A. 680:447-453
Scrapie in sheep and goats causes a progressive, degenerative disease of the central nervous system and is the prototype of other transmissible spongiform encephalopathies (TSE) found in humans and in animals. In samples of TSE-affected brains, uniqu
Autor:
Kathryn R. Goodwin, Mary Jo Schmerr
Publikováno v:
Journal of Chromatography A. 652:199-205
Ovine lentiviruses are a group of viruses that infect sheep and goats. These viruses contain a surface glycoprotein (SU) that is very similar among the viral strains. Sera from infected animals react equally well with SU from each strain. Monoclonal
Autor:
Mary Jo Schmerr, Kathryn R. Goodwin
Publikováno v:
Comparative Immunology, Microbiology and Infectious Diseases. 14:289-295
A method using protein A-Sepharose chromatography was developed to separate and purify ovine IgG1 and IgG2. The IgG1 eluted from protein A-Sepharose at pH 6.8 and IgG2 eluted at pH 4.5. This method was used to show the specific transfer of IgG1 from
Autor:
Bulgin Ms, A. N. Hamir, Randall C. Cutlip, Kathryn R. Goodwin, Janice M. Miller, Mary Jo Schmerr, Allen L. Jenny
Publikováno v:
Journal of chromatography. A. 853(1-2)
Transmissible spongiform encephalopathies in humans and in animals are fatal neuro-degenerative diseases with long incubation times. The putative cause of these diseases is a normal host protein, the prion protein, that becomes altered. This abnormal
Publikováno v:
Journal of chromatography. B, Biomedical applications. 681(1)
Scrapie in sheep and goats is the prototype of transmissible spongiform encephalopathies found in humans and animals. A feature of these diseases is the accumulation of rod-shaped fibrils in the brain that form from an aggregated protein. This protei
Publikováno v:
Journal of Chromatography A. 326:225-233
High-performance anion-exchange chromatography (HPIEC) and high-performance size-exclusion chromatography (HPSEC) wereused to purify serum IgM and IgG from sheep and cattle. Pooled serum from normal cattle and sheep and serum from sheep, infected wit
Autor:
Kathryn R. Goodwin, Mary Jo Schmerr
Publikováno v:
Veterinary immunology and immunopathology. 2(3)
The sensitivity of the radioimmunoprecipitation assay for the major internal protein (p24) of bovine leukemia virus (BLV) was examined. Conditions were varied for the assay by 1) using larger amounts of serum and 2) increasing the amount of second an
Autor:
Brian K. Nunnally, Ira S. Krull
The alarm sounded by Canada's confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research convergi