Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kathryn R. Brewer"'
Autor:
Kathryn R. Brewer, Georg Kuenze, Carlos G. Vanoye, Alfred L. George, Jens Meiler, Charles R. Sanders
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The cardiac action potential is critical to the production of a synchronized heartbeat. This electrical impulse is governed by the intricate activity of cardiac ion channels, among them the cardiac voltage-gated potassium (Kv) channels KCNQ1 and hERG
Externí odkaz:
https://doaj.org/article/9513fb6290644222a02f780f87dc44b7
Autor:
Georg Kuenze, Amanda M Duran, Hope Woods, Kathryn R Brewer, Eli Fritz McDonald, Carlos G Vanoye, Alfred L George, Charles R Sanders, Jens Meiler
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0220415 (2019)
The voltage-gated potassium channel KCNQ1 (KV7.1) assembles with the KCNE1 accessory protein to generate the slow delayed rectifier current, IKS, which is critical for membrane repolarization as part of the cardiac action potential. Loss-of-function
Externí odkaz:
https://doaj.org/article/34428767e7f74f1ab409652801eb3dd6
Autor:
Sneha Adusumilli, Hope Woods, Charles R. Sanders, Jens Meiler, Georg Kuenze, Carlos G. Vanoye, Reshma R. Desai, Eli Fritz McDonald, Alfred G. George, Kathryn R. Brewer
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The function of the voltage-gated KCNQ1 potassium channel is regulated by co-assembly with KCNE auxiliary subunits. KCNQ1-KCNE1 channels generate the slow delayed rectifier current, IKs, which contributes to the repolarization phase of the cardiac ac
Autor:
Charles R. Sanders, Sneha Adusumilli, Eli Fritz McDonald, Jens Meiler, Hope Woods, Kathryn R. Brewer, Carlos G. Vanoye, Reshma R. Desai, Georg Kuenze, Alfred L. George
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6e8f51521c058ddd362cb8820e66236
https://doi.org/10.7554/elife.57680.sa2
https://doi.org/10.7554/elife.57680.sa2
Autor:
Charles R. Sanders, Eli Fritz McDonald, Jens Meiler, Hope Woods, Alfred L. George, Amanda M. Duran, Carlos G. Vanoye, Georg Kuenze, Kathryn R. Brewer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0220415 (2019)
PLoS ONE, Vol 14, Iss 9, p e0220415 (2019)
The voltage-gated potassium channel KCNQ1 (KV7.1) assembles with the KCNE1 accessory protein to generate the slow delayed rectifier current, IKS, which is critical for membrane repolarization as part of the cardiac action potential. Loss-of-function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cbb25bc120791e355c23217cf3b188
Publikováno v:
Biophysical Journal. 120:241a
Publikováno v:
Biophysical Journal. 118:263a
Autor:
Georg Kuenze, Carlos G Vanoye, Reshma R Desai, Sneha Adusumilli, Kathryn R Brewer, Hope Woods, Eli F McDonald, Charles R Sanders, Alfred L George Jr, Jens Meiler
Publikováno v:
eLife, Vol 9 (2020)
The function of the voltage-gated KCNQ1 potassium channel is regulated by co-assembly with KCNE auxiliary subunits. KCNQ1-KCNE1 channels generate the slow delayed rectifier current, IKs, which contributes to the repolarization phase of the cardiac ac
Externí odkaz:
https://doaj.org/article/eb5503437d7d4717b295c6786fb43fec