Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kathryn Patton"'
Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer
Autor:
Fan Yang, Wing Yen Wong, Stephen J. Zoog, Hassibullah Akeefe, Elli Koziol, Christian Vettermann, Jennifer Holcomb, Annie Clark, Kevin Hammon, Joshua Henshaw, Nina Mitchell, Kathryn Patton, Krystal Sandza, Benjamin Kim
Publikováno v:
Gene Therapy. 29:94-105
Adeno-associated virus (AAV)-based gene therapy vectors are replication-incompetent and thus pose minimal risk for horizontal transmission or release into the environment. In studies with AAV5-FVIII-SQ (valoctocogene roxaparvovec), an investigational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ba614012286642560de73bd2c68659
https://doi.org/10.1038/s41434-021-00287-1
https://doi.org/10.1038/s41434-021-00287-1
Autor:
Stephen J. Zoog, Christian Vettermann, Theresa Kasprzyk, Brian Long, Kathryn Patton, Soumi Gupta, Kristin Tracy, Fan Yang
Publikováno v:
Gene Therapy
Adeno-Associated Virus (AAV)-based gene therapy vectors are in development for many inherited human disorders. In nonclinical studies, cellular immune responses mediated by cytotoxic T cells may target vector-transduced cells, which could impact safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a783a48087bda0b6f41f2471cb96fab3
https://doi.org/10.1038/s41434-020-00214-w
https://doi.org/10.1038/s41434-020-00214-w
Autor:
Brian Long, Sylvia Fong, Britta Handyside, Tara Robinson, Jonathan Day, Hua Yu, Kelly Lau, Kathryn Patton, Greg de Hart, Josh Henshaw, Suresh Agarwal, Christian Vettermann, Soumi Gupta
Publikováno v:
Journal of Hepatology. 77:S540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d30101436f50fd764cdcfd4a654e5a1
https://doi.org/10.1016/s0168-8278(22)01404-0
https://doi.org/10.1016/s0168-8278(22)01404-0
Publikováno v:
Obstetrics & Gynecology. 139:82S-82S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::570d9c649e1a3a2536ec14d116277d5c
https://doi.org/10.1097/01.aog.0000825700.12191.88
https://doi.org/10.1097/01.aog.0000825700.12191.88
Autor:
Anu Cherukuri, Stacie L. Lambert, Jennifer Woo, Li Yu, Mark T. Esser, Jim Lin, Glenn Dawes, Sylvia Janetzki, Shahin Aslam, Kathryn Patton
Publikováno v:
Clinical and Vaccine Immunology. 21:628-635
Respiratory syncytial virus (RSV) causes significant disease in elderly adults, and we have previously reported that individuals 65 years of age and older have reduced RSV F protein-specific gamma interferon (IFN-γ)-producing T cells compared to hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd54917f94aac1d767afb22f7bbfb40
https://doi.org/10.1128/cvi.00736-13
https://doi.org/10.1128/cvi.00736-13
Autor:
Chris Frantz, Rui Lin, Fengrong Zuo, Kathryn Patton, Shahin Aslam, Xavier Paliard, Stacie L. Lambert, Darren S. Heeke, Mark T. Esser, Cindy Shambaugh
Publikováno v:
Vaccine. 33(36)
Respiratory syncytial virus (RSV) causes significant disease in elderly adults, but an effective vaccine is not yet available. We have previously reported that vaccines consisting of engineered respiratory syncytial virus soluble fusion protein (RSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db92ae399a2f3e37d8aa6e3fcdc0689
https://pubmed.ncbi.nlm.nih.gov/26206269
https://pubmed.ncbi.nlm.nih.gov/26206269
Publikováno v:
Blood. 85:2587-2597
The function of the zeta-globin promoter was studied using a series of zeta-globin promoter deletion constructs to drive luciferase expression in transiently transfected human erythroleukemia cells. The promoters were used without enhancers, or with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f0b59d7793dbc5c79c9d20c40e7870
https://doi.org/10.1182/blood.v85.9.2587.bloodjournal8592587
https://doi.org/10.1182/blood.v85.9.2587.bloodjournal8592587
Autor:
Kaori Sakamoto, Anu Cherukuri, Sujin Lee, Stacie L. Lambert, Howard Kuo, Kate L. Stokes, Kathryn Patton, Elizabeth Ann Stillman, Martin L. Moore
Publikováno v:
Immunity & Ageing, Vol 9, Iss 1, p 21 (2012)
Immunity & Ageing : I & A
Immunity & Ageing : I & A
Background Respiratory Syncytial Virus (RSV) causes significant disease in the elderly, in part, because immunosenescence impairs protective immune responses to infection in this population. Despite previous and current efforts, there is no RSV vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df2656f076253d2c3807c7b506c6392
http://www.immunityageing.com/content/9/1/21
http://www.immunityageing.com/content/9/1/21
Autor:
Myung Sook Huh, Kyung Dall Lee, Chasity D. Andrews, Kathryn Patton, Gary Van Nest, Gary Ott, Debbie Higgins
Publikováno v:
Molecular pharmaceutics. 9(5)
Immunostimulatory sequences (ISS) are short DNA sequences containing unmethylated CpG dimers that have multiple effects on the host immune system, including the ability to stimulate antigen-specific cytotoxic T lymphocytes (CTLs) and drive Th1-type i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee84cc21b13b80721fda5eccfd93cbc
https://pubmed.ncbi.nlm.nih.gov/22376145
https://pubmed.ncbi.nlm.nih.gov/22376145
Autor:
Stacie L. Lambert, Shahin Aslam, Fengrong Zuo, Andrew J. Pierce, Cindy Shambaugh, Li Yu, Darren S. Heeke, Xavier Paliard, Kathryn Patton, Rui Lin
Publikováno v:
Journal of Clinical Oncology. 33:3086-3086
3086 Background: Immunomodulatory antibodies targeting specific T cell costimulatory pathways have shown great potential as cancer therapeutics. OX40 agonists can enhance T cell proliferation and s...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4508ee7e8572d7707077ec18f829916
https://doi.org/10.1200/jco.2015.33.15_suppl.3086
https://doi.org/10.1200/jco.2015.33.15_suppl.3086