Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Kathryn P Burdon"'
Autor:
Rajya L Gurung, Liesel M FitzGerald, Ebony Liu, Bennet J McComish, Georgia Kaidonis, Bronwyn Ridge, Alex W Hewitt, Brendan J Vote, Nitin Verma, Jamie E Craig, Kathryn P Burdon
Publikováno v:
International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections are the standard of care for diabetic macular edema (DME), a common complication of diabetes. This study aimed to identify factors influencing DME intravi
Externí odkaz:
https://doaj.org/article/c30b9b2eaa33494fbc814d635db0810a
Autor:
David A Mackey, Emmanuelle Souzeau, Jamie E Craig, Jonathan B Ruddle, Bennet J McComish, Kathryn P Burdon, Jac C Charlesworth, Sandra E Staffieri, Johanna L Jones, Lisa S Kearns, James E Elder, Deepa Taranath, John Pater, Theresa Casey
Publikováno v:
BMJ Open Ophthalmology, Vol 7, Iss 1 (2022)
Objective Paediatric (childhood or congenital) cataract is an opacification of the normally clear lens of the eye and has a genetic basis in at least 18% of cases in Australia. This study aimed to replicate clinical gene screening to identify variant
Externí odkaz:
https://doaj.org/article/4531117e512f447886a812c832faec19
Publikováno v:
BMJ Open Ophthalmology, Vol 6, Iss 1 (2021)
Objective To compare the visual outcomes of intravitreal antivascular endothelial growth factor (anti-VEGF) injections in neovascular age-related macular degeneration (nAMD), diabetic macular oedema (DMO) and retinal vein occlusion (RVO) in a real-wo
Externí odkaz:
https://doaj.org/article/df30b0a1f0954c74ac370e9b5ee3e385
Autor:
Sionne E M Lucas, Tiger Zhou, Nicholas B Blackburn, Richard A Mills, Jonathan Ellis, Paul Leo, Emmanuelle Souzeau, Bronwyn Ridge, Jac C Charlesworth, Richard Lindsay, Jamie E Craig, Kathryn P Burdon
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199178 (2018)
Many genes have been suggested as candidate genes for keratoconus based on their function, their proximity to associated polymorphisms or due to the identification of putative causative variants within the gene. However, very few of these genes have
Externí odkaz:
https://doaj.org/article/e6f63ae78328415b8502f342c7e7c192
Autor:
Abraham Kuot, Alex W Hewitt, Grant R Snibson, Emmanuelle Souzeau, Richard Mills, Jamie E Craig, Kathryn P Burdon, Shiwani Sharma
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183719 (2017)
Fuchs' endothelial corneal dystrophy (FECD) is a progressive, vision impairing disease. Common single nucleotide polymorphisms (SNPs) and a trinucleotide repeat polymorphism, thymine-guanine-cytosine (TGC), in the TCF4 gene have been associated with
Externí odkaz:
https://doaj.org/article/3f25a806caa345e590335d658fae7e20
Autor:
Tiger Zhou, Emmanuelle Souzeau, Shiwani Sharma, John Landers, Richard Mills, Ivan Goldberg, Paul R Healey, Stuart Graham, Alex W Hewitt, David A Mackey, Anna Galanopoulos, Robert J Casson, Jonathan B Ruddle, Jonathan Ellis, Paul Leo, Matthew A Brown, Stuart MacGregor, David J Lynn, Kathryn P Burdon, Jamie E Craig
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172427 (2017)
PURPOSE:To identify biological processes associated with POAG and its subtypes, high-tension (HTG) and normal-tension glaucoma (NTG), by analyzing rare potentially damaging genetic variants. METHODS:A total of 122 and 65 unrelated HTG and NTG partici
Externí odkaz:
https://doaj.org/article/2afdebc80a9b4a408114345178205702
Autor:
Nicole J Van Bergen, Jonathan G Crowston, Jamie E Craig, Kathryn P Burdon, Lisa S Kearns, Shiwani Sharma, Alex W Hewitt, David A Mackey, Ian A Trounce
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140919 (2015)
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the selective and gradual loss of retinal ganglion cells (RGCs). Aging and increased intraocular pressure (IOP) are glaucoma risk factors; nevertheless patients
Externí odkaz:
https://doaj.org/article/85611cb6ab6742079f21386c3150103f
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67903 (2013)
PurposeA recent large genome-wide association study (GWAS) identified multiple variants associated with primary angle-closure glaucoma (PACG). The present study investigated the role of these variants in two cohorts with PACG recruited from Australia
Externí odkaz:
https://doaj.org/article/a0b38d44aa3d4fdcb0968f1293aa588f
Autor:
Glyn Chidlow, John P M Wood, Shiwani Sharma, David P Dimasi, Kathryn P Burdon, Robert J Casson, Jamie E Craig
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75067 (2013)
It has recently been shown that there are highly significant associations for common single nucleotide polymorphisms (SNPs) near the CDKN2B-AS1 gene region at the 9p21 locus with primary open angle glaucoma (POAG), a leading cause of irreversible bli
Externí odkaz:
https://doaj.org/article/d6ebf5f55bf541d0b5457a12e13110d7
Autor:
Alpana Dave, Kate Laurie, Sandra E Staffieri, Deepa Taranath, David A Mackey, Paul Mitchell, Jie Jin Wang, Jamie E Craig, Kathryn P Burdon, Shiwani Sharma
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72518 (2013)
Congenital cataract is the most common cause of treatable visual impairment in children worldwide. Mutations in many different genes lead to congenital cataract. Recently, mutations in the receptor tyrosine kinase gene, EPHA2, have been found to caus
Externí odkaz:
https://doaj.org/article/909f672fe1d842d7b2756194fa3d4f28