Development of Non-Viral, Trophoblast-Specific Gene Delivery for Placental Therapy.

Autor: Noura Abd Ellah, Leeanne Taylor, Weston Troja, Kathryn Owens, Neil Ayres, Giovanni Pauletti, Helen Jones

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0140879 (2015)

Low birth weight is associated with both short term problems and the fetal programming of adult onset diseases, including an increased risk of obesity, diabetes and cardiovascular disease. Placental insufficiency leading to intrauterine growth restri

Externí odkaz: https://doaj.org/article/2213c310649543849834a4e8a2e6b494

Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the great arteries

Autor: Robert B. Hinton, Andrea C. Hinton, Weston Troja, Heather Brockway, James F. Cnota, Jennifer Courtney, Kathryn Owens, Helen Jones

Publikováno v: Placenta. 101:57-65

Background Birthweight is a critical predictor of congenital heart disease (CHD) surgical outcomes. Hypoplastic left heart syndrome (HLHS) is cyanotic CHD with known fetal growth restriction and placental abnormalities. Transposition of the great art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794151e14ab630c59bc242431c9863df
https://doi.org/10.1016/j.placenta.2020.09.007

Nanoparticle mediated increased insulin-like growth factor 1 expression enhances human placenta syncytium function

Autor: Natalia Schlabritz-Loutsevitch, Matthew V. Fry, Marcel Chuecos, Rebecca L. Wilson, Helen Jones, Kathryn Owens, Emily K Sumser, Kendal K. Stephens, Maira Carrillo

Publikováno v: Placenta

INTRODUCTION: Placental dysfunction is an underlying cause of many major obstetric diseases and treatment options for complications like fetal growth restriction (FGR) are limited. We previously demonstrated nanoparticle delivery of the human insulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f1275835a20201c9dd8bd6698f630a
https://pubmed.ncbi.nlm.nih.gov/32090963

CD200-CD200R imbalance correlates with microglia and pro-inflammatory activation in rat spinal cords exposed to amniotic fluid in retinoic acid-induced spina bifida

Autor: Rebeca Lopes Figueira, Federico Scorletti, Mario Marotta, Zhen Li, Marc Oria, Bedika Pathak, Lourenço Sbragia, Jose L. Peiro, Jose Luis Encinas, Kathryn Owens, Maria U. Corona

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)

Spina bifida aperta is a congenital malformation characterized by the failure of neural tube closure resulting in an unprotected fetal spinal cord. The spinal cord then undergoes progressive damage, likely due to chemical and mechanical factors relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e55e7ddffd4b5a386637013253c5b5

Autophagic flux in glioblastoma cells

Autor: Richard J. Becker, Christine Andorf, T. Kroc, Kathryn Owens, Linda S. Yasui, Kelsie Allen-Durdan, Scott Grayburn, Maria Duran, Andrew Schuck

Publikováno v: International journal of radiation biology. 92(11)

To establish metabolic context for radiation sensitivity by measuring autophagic flux in two different glioblastoma (GBM) cell lines. Clonogenic survival curve analysis of U87 or U251 cells exposed to γ radiation, fast neutrons, a mixed energy neutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f3ff9f969abc76139d76a051e42030
https://pubmed.ncbi.nlm.nih.gov/26967573