Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathryn McAvoy"'
Autor:
Kathryn McAvoy, Helen O. McCarthy, Maelíosa T.C. McCrudden, Aaron J. Courtenay, Ryan F. Donnelly
Publikováno v:
Courtenay, A J, McCrudden, M T C, McAvoy, K J, McCarthy, H O & Donnelly, R F 2018, ' Microneedle-Mediated Transdermal Delivery of Bevacizumab ', Molecular Pharmaceutics, vol. 15, no. 8, pp. 3545-3556 . https://doi.org/10.1021/acs.molpharmaceut.8b00544
Bevacizumab is a recombinant humanized monoclonal antibody used clinically as a combination chemotherapeutic. Antibody therapeutics are usually formulated as parenteral injections, owing to their low oral bioavailability. Microneedle technology provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09373f04e4c5d20f0a9f1471639d11de
https://pure.qub.ac.uk/en/publications/microneedlemediated-transdermal-delivery-of-bevacizumab(c1d67692-9add-41d4-a1b0-556fa7c027b4).html
https://pure.qub.ac.uk/en/publications/microneedlemediated-transdermal-delivery-of-bevacizumab(c1d67692-9add-41d4-a1b0-556fa7c027b4).html
Publikováno v:
McAvoy, K, Jones, D & Thakur, R R S 2018, ' Synthesis and characterisation of photocrosslinked poly(ethylene glycol) diacrylate implants for sustained ocular drug delivery ', Pharmaceutical Research, vol. 35, no. 2, 36 . https://doi.org/10.1007/s11095-017-2298-9
Pharmaceutical Research
Pharmaceutical Research
PurposeTo investigate the sustained ocular delivery of small and large drug molecules from photocrosslinked poly(ethylene glycol) diacrylate (PEGDA) implants with varying pore forming agents.MethodsTriamcinolone acetonide and ovalbumin loaded photocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686436de1aa41ea31711d7667c48ab1
https://pure.qub.ac.uk/en/publications/synthesis-and-characterisation-of-photocrosslinked-polyethylene-glycol-diacrylate-implants-for-sustained-ocular-drug-delivery(62d60bf2-030a-479b-ac50-80e56d4cc8fa).html
https://pure.qub.ac.uk/en/publications/synthesis-and-characterisation-of-photocrosslinked-polyethylene-glycol-diacrylate-implants-for-sustained-ocular-drug-delivery(62d60bf2-030a-479b-ac50-80e56d4cc8fa).html
Autor:
Hannah McMillan, David S. Jones, Kathryn McAvoy, Ryan F. Donnelly, Raghu Raj Thakur Singh, Ismaiel Tekko
Publikováno v:
Thakur, R, Tekko, I, McAvoy, K, Donnelly, R F, McMillian, H & Jones, D 2017, ' Minimally invasive microneedles for ocular drug delivery ', Expert Opinion on Drug Delivery, vol. 14, no. 4, pp. 525-537 . https://doi.org/10.1080/17425247.2016.1218460, https://doi.org/10.1080/17425247.2016.1218460
Introduction: Anterior and posterior segment eye diseases are highly challenging to treat, due to the barrier properties and relative inaccessibility of the ocular tissues. Topical eye drops and systemically delivered treatments result in low bioavai