Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathryn M. Stevens"'
Autor:
Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark, Christian Speck
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Here the authors describe multiple structures of the replicative helicase MCM2-7 in complex with Dbf4-dependent kinase (DDK). These structures reveal why the kinase specifically recognizes the MCM2-7 double-hexamer over the single-hexamer and explain
Externí odkaz:
https://doaj.org/article/1c4e6e876ce4469480a77bd86fddffbb
Publikováno v:
eLife, Vol 8 (2019)
Nucleosomes restrict DNA accessibility throughout eukaryotic genomes, with repercussions for replication, transcription, and other DNA-templated processes. How this globally restrictive organization emerged during evolution remains poorly understood.
Externí odkaz:
https://doaj.org/article/af07d7a9c42b4850994981dc44b0dfa4
Autor:
Antoine Hocher, Shawn P. Laursen, Paul Radford, Jess Tyson, Carey Lambert, Kathryn M Stevens, Mathieu Picardeau, R. Elizabeth Sockett, Karolin Luger, Tobias Warnecke
Histones are the principal constituents of chromatin in eukaryotes and most archaea, while bacteria generally rely on an orthogonal set of proteins to organize their chromosomes. However, several bacterial genomes encode proteins with putative histon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072b3d8c9027c760bfcba2e524ae154a
https://doi.org/10.1101/2023.01.26.525422
https://doi.org/10.1101/2023.01.26.525422
Autor:
Antoine Hocher, Simonetta Gribaldo, Corinna Bang, Ruth A. Schmitz, Kathryn M Stevens, Tobias Warnecke, Jacob B Swadling
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Chromatin in eukaryotes is built around histone–DNA complexes, which act as platforms for the integration of regulatory information. Different layers of information are integrated in a combinatorial fashion, for example by exchanging c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5a2958890b14a0a19721194416ffcd
https://doi.org/10.1073/pnas.2007056117
https://doi.org/10.1073/pnas.2007056117
Autor:
Kathryn M, Stevens, Tobias, Warnecke
Exchanging core histones in the nucleosome for paralogous variants can have important functional ramifications. Many of these variants, and their physiological roles, have been characterized in exquisite detail in model eukaryotes, including humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a641d6803cbc555a7e651894541b8441
http://hdl.handle.net/10044/1/95818
http://hdl.handle.net/10044/1/95818
Publikováno v:
Genome Biology and Evolution
Histones are ubiquitous in eukaryotes where they assemble into nucleosomes, binding and wrapping DNA to form chromatin. One process to modify chromatin and regulate DNA accessibility is the replacement of histones in the nucleosome with paralogous va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34230baaf9657a8ef55d6c7f924cc4e6
http://europepmc.org/articles/PMC8775648
http://europepmc.org/articles/PMC8775648
Histones are ubiquitous in eukaryotes where they assemble into nucleosomes, binding and wrapping DNA to form chromatin. One process to modify chromatin and regulate DNA accessibility is the replacement of histones in the nucleosome with paralogous va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0172f5d2645252fedeb6de6a8261cac3
https://doi.org/10.1101/2021.09.07.455978
https://doi.org/10.1101/2021.09.07.455978
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Nucleosomes restrict DNA accessibility throughout eukaryotic genomes, with repercussions for replication, transcription, and other DNA-templated processes. How this globally restrictive organization emerged during evolution remains poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2617dac12edce8e9d1305d5e02318b70
https://doi.org/10.7554/elife.49038
https://doi.org/10.7554/elife.49038