Phages are unrecognized players in the ecology of the oral pathogen Porphyromonas gingivalis

Autor: Cole B. Matrishin, Elaine M. Haase, Floyd E. Dewhirst, Jessica L. Mark Welch, Fabiola Miranda-Sanchez, Tsute Chen, Donald C. MacFarland, Kathryn M. Kauffman

Publikováno v: Microbiome, Vol 11, Iss 1, Pp 1-25 (2023)

Abstract Background Porphyromonas gingivalis (hereafter “Pg”) is an oral pathogen that has been hypothesized to act as a keystone driver of inflammation and periodontal disease. Although Pg is most readily recovered from individuals with actively

Externí odkaz: https://doaj.org/article/28465228b6294741854fc288d0c8170d

Streamlining standard bacteriophage methods for higher throughput

Autor: Kathryn M. Kauffman, Martin F. Polz

Publikováno v: MethodsX, Vol 5, Iss , Pp 159-172 (2018)

A universal tool in the culture-based study of bacterial viruses (bacteriophages, or phages) is the agar overlay, which is used in the isolation of new viruses, and in their quantification and purification. Here, simple optimizations that increase ef

Externí odkaz: https://doaj.org/article/f23f64221087459d85f589f2ed6b6e3b

Phage-host coevolution in natural populations

Autor: Damien Piel, Maxime Bruto, Yannick Labreuche, François Blanquart, David Goudenège, Rubén Barcia-Cruz, Sabine Chenivesse, Sophie Le Panse, Adèle James, Javier Dubert, Bruno Petton, Erica Lieberman, K. Mathias Wegner, Fatima A. Hussain, Kathryn M. Kauffman, Martin F. Polz, David Bikard, Sylvain Gandon, Eduardo P. C. Rocha, Frédérique Le Roux

Publikováno v: Nature Microbiology
Nature Microbiology, 2022, 7 (7), pp.1075-1086. ⟨10.1038/s41564-022-01157-1⟩
Nature Microbiology, 2022, 7, pp.1075-1086. ⟨10.1038/s41564-022-01157-1⟩
Nature Microbiology (2058-5276) (Springer Science and Business Media LLC), 2022-07, Vol. 7, N. 7, P. 1075-1086

International audience; Coevolution between bacteriophages (phages) and their bacterial hosts occurs through changes in resistance and counter-resistance mechanisms. To assess phage-host evolution in wild populations, we isolated 195 Vibrio crassostr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbb61d4bdf45bbf2a57dad7428c6d54
https://hal.science/hal-03738913/document

Growth of marine Vibrio in oligotrophic environments is not stimulated by the addition of inorganic iron

Autor: Amber K. Reid, Michael J. Follows, Kathryn M. Kauffman, Seth G. John, Rachel L. Kelly, Jonathan Maitland Lauderdale, Ruifeng Zhang

Publikováno v: Earth and Planetary Science Letters. 516:148-155

Phytoplankton growth in many high-latitude and equatorial regions of the world ocean is limited by low iron (Fe), while regions of lower nutrient upwelling and higher dust supply such as the subtropical gyres are typically not considered Fe-limited.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95735276e1b0c32333594731be41e4cf
https://doi.org/10.1016/j.epsl.2019.04.002

Rapid evolutionary turnover of mobile genetic elements drives microbial resistance to viruses

Autor: David VanInsberghe, Murphy M, Kotska Rodino-Janeiro B, Kathryn M. Kauffman, Fatima A. Hussain, Joseph Elsherbini, Philip Arevalo, Martin F. Polz, Javier Dubert

Although it is generally accepted that viruses (phages) drive bacterial evolution, how these dynamics play out in the wild remains poorly understood. Here we show that the arms race between phages and their hosts is mediated by large and highly diver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::719a36a2e4c79c62ea3707d71c0a0b45
https://doi.org/10.1101/2021.03.26.437281