Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathryn M. Headley"'
Autor:
Kathryn M. Headley, Katarzyna M. Kedziora, Aidin Alejo, Elianna Zhi-Xiang Lai, Jeremy E. Purvis, Nathaniel A. Hathaway
Publikováno v:
Stem Cell Research, Vol 38, Iss , Pp - (2019)
Here we utilized the chromatin in vivo assay (CiA) mouse platform to directly examine the epigenetic barriers impeding the activation of the CiA:Oct4 allele in mouse embryonic fibroblasts (MEF)s when stimulated with a transcription factor. The CiA:Oc
Externí odkaz:
https://doaj.org/article/32351aaaf3894319a827aa5bbfe3b5ad
Autor:
Wanjuan Feng, Jang-Eun Cho, Nate Hathaway, Chelsea M. Smith, Juan Carvajal-Garcia, Dennis A. Simpson, Dale A. Ramsden, Kathryn M. Headley, Gaorav P. Gupta
Publikováno v:
Nucleic Acids Research
Genome integrity and genome engineering require efficient repair of DNA double-strand breaks (DSBs) by non-homologous end joining (NHEJ), homologous recombination (HR), or alternative end-joining pathways. Here we describe two complementary methods f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676e480a4c0772af2eb4d96aa8906c2c
https://pubmed.ncbi.nlm.nih.gov/33963863
https://pubmed.ncbi.nlm.nih.gov/33963863
Autor:
Katarzyna M. Kedziora, Kathryn M. Headley, Nathaniel A. Hathaway, Aidin Alejo, Jeremy E. Purvis, Elianna Zhi-Xiang Lai
Publikováno v:
Stem Cell Research, Vol 38, Iss, Pp-(2019)
Stem cell research
Stem cell research
Here we utilized the chromatin in vivo assay (CiA) mouse platform to directly examine the epigenetic barriers impeding the activation of the CiA:Oct4 allele in mouse embryonic fibroblasts (MEF)s when stimulated with a transcription factor. The CiA:Oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f717ba0d7329eabb5ed08378d9d994c
http://www.sciencedirect.com/science/article/pii/S187350611930100X
http://www.sciencedirect.com/science/article/pii/S187350611930100X
Autor:
Bethanie L. Morrison, Joe J. Mitala, Joseph M. Reilly, Kathryn M. Headley, Kevin A. Murray, Federico Bernal, Amanda L. Whiting
Publikováno v:
Cancer Research. 74:3234-3234
Mutations in the DNA binding region of tumor suppressor p53 render it transcriptionally inactive (dominant negative) but can also manifest in transcriptionally-independent gain-of-function (GOF) effects, possibly due to mutp53 interacting with other,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86d3cde1af4eb34117427b20cbf88587
https://doi.org/10.1158/1538-7445.am2014-3234
https://doi.org/10.1158/1538-7445.am2014-3234
Autor:
Federico Bernal, Kenneth Felsenstein, Elisabeth A. Russell, Kathryn M. Headley, Kevin A. Murray
Publikováno v:
Cancer Research. 73:2223-2223
Considered to be the “guardian of the genome,” the tumor suppressor p53 works to counteract genetic mutation through cell cycle arrest, DNA repair or apoptosis to prevent proliferation of damaged cells. Dysfunction of the p53 pathway is a large d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6a01fc7820ce2343a5a9451d9151e7b
https://doi.org/10.1158/1538-7445.am2013-2223
https://doi.org/10.1158/1538-7445.am2013-2223