Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kathryn M. Harper"'
Autor:
Shenée C. Martin, Kathryn K. Joyce, Kathryn M. Harper, Samuel J. Harp, Todd J. Cohen, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 319 (2024)
Sleep disruption is an expected component of aging and neurodegenerative conditions, including Alzheimer’s disease (AD). Sleep disruption has been demonstrated as a driver of AD pathology and cognitive decline. Therefore, treatments designed to mai
Externí odkaz:
https://doaj.org/article/7e26de891f7f48d69a3dc5e4560420ae
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Neurodevelopmental disorders (NDDs) are complex conditions characterized by heterogeneous clinical profiles and symptoms that arise in infancy and childhood. NDDs are often attributed to a complicated interaction between genetic risk and environmenta
Externí odkaz:
https://doaj.org/article/43614a25a06f4d2694b5d170de08c09b
Autor:
Julia S. Lord, Sean M. Gay, Kathryn M. Harper, Viktoriya D. Nikolova, Kirsten M. Smith, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Patients with autism spectrum disorder (ASD) experience high rates of sleep disruption beginning early in life; however, the developmental consequences of this disruption are not understood. We examined sleep behavior and the cons
Externí odkaz:
https://doaj.org/article/c5e745d47c3941baa4b107535e8ce93b
Autor:
Jessica A. Jiménez, Jeremy M. Simon, Wenxin Hu, Sheryl S. Moy, Kathryn M. Harper, Chih-Wei Liu, Kun Lu, Mark J. Zylka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Hundreds of genes have been associated with autism spectrum disorder (ASD), including loss-of-function mutations in chromodomain helicase DNA binding protein 8 (Chd8). Environmental factors also are implicated in autism risk and have the pot
Externí odkaz:
https://doaj.org/article/04768033bf0245a198afb592fc2b8afe
Autor:
R. Oliver Goral, Kathryn M. Harper, Briana J. Bernstein, Sydney A. Fry, Patricia W. Lamb, Sheryl S. Moy, Jesse D. Cushman, Jerrel L. Yakel
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Introduction: Altered signaling or function of acetylcholine (ACh) has been reported in various neurological diseases, including Alzheimer’s disease, Tourette syndrome, epilepsy among others. Many neurons that release ACh also co-transmit the neuro
Externí odkaz:
https://doaj.org/article/37d07ecc33924efab4a32cc003faff10
Autor:
Kathryn M. Harper, Darin J. Knapp, Caroline A. Todd, Irina Balan, Laure Aurelian, Hugh E. Criswell, George R. Breese
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Chemokines such as chemokine (C-C motif) ligand 2 (CCL2) play a role in several behaviors, including anxiety-like behavior, but whether neurons are an important source of CCL2 for behavior and how neuronal CCL2 may work to affect behavior are still d
Externí odkaz:
https://doaj.org/article/bd0e8ceac01045ddae6df7b3817fe7e3
Publikováno v:
Brain Sciences, Vol 6, Iss 3, p 25 (2016)
Stress is a strong risk factor in alcoholic relapse and may exert effects that mimic aspects of chronic alcohol exposure on neurobiological systems. With the neuroimmune system becoming a prominent focus in the study of the neurobiological consequenc
Externí odkaz:
https://doaj.org/article/a5e0ab2dc4294a32be79c632c5d935c3
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44790c896a16c53de4ff0af2234b18bc
https://doi.org/10.1007/978-1-0716-2752-5_14
https://doi.org/10.1007/978-1-0716-2752-5_14
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2583
Behavioral phenotyping approaches for neonatal mice are important for investigating early alterations in brain development and function, relevant to neurodevelopmental disorders in humans. This chapter describes a behavioral screen that can provide a
Autor:
Jessica A, Jiménez, Jeremy M, Simon, Wenxin, Hu, Sheryl S, Moy, Kathryn M, Harper, Chih-Wei, Liu, Kun, Lu, Mark J, Zylka
Publikováno v:
Scientific reports. 12(1)
Hundreds of genes have been associated with autism spectrum disorder (ASD), including loss-of-function mutations in chromodomain helicase DNA binding protein 8 (Chd8). Environmental factors also are implicated in autism risk and have the potential to