Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kathryn M. Gill"'
Publikováno v:
Schizophr Res
Abnormalities in resting-state electroencephalogram (rs-EEG) activity have been previously reported in schizophrenia. While most rs-EEG recordings were performed in patients with chronic schizophrenia during eyes closed (EC), only a handful of studie
Publikováno v:
Schizophrenia Research. 206:318-324
Background Sleep disturbances are commonly reported in psychotic patients and often contribute to the manifestation and severity of their symptoms. Slow waves characterize the deepest stage of NREM sleep, and their occurrence is critical for restorat
Publikováno v:
Neuropsychopharmacology. 44:572-580
Aripiprazole is an antipsychotic drug characterized by partial agonist activity at D2 receptors to normalize both hyperdopaminergic and hypodopaminergic states. Traditional D2 antagonist antipsychotic drugs have been shown previously to reduce dopami
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 44(3)
Aripiprazole is an antipsychotic drug characterized by partial agonist activity at D(2) receptors to normalize both hyperdopaminergic and hypodopaminergic states. Traditional D(2) antagonist antipsychotic drugs have been shown previously to reduce do
The methylazoxymethanol acetate (MAM) rodent neurodevelopmental model of schizophrenia exhibits aberrant dopamine system activation attributed to hippocampal dysfunction. Context discrimination is a component of numerous behavioral and cognitive func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06592dced6362df8c682e40920908dc
https://europepmc.org/articles/PMC5854517/
https://europepmc.org/articles/PMC5854517/
Autor:
Kathryn M. Gill, Anthony A. Grace
Publikováno v:
Current Pharmaceutical Design. 20:5069-5076
Currently available pharmacotherapies for the treatment of schizophrenia are ineffective in restoring the disrupted cognitive function associated with this disorder. As such, there is a continued search for more viable novel drug targets. Engaging in
Autor:
Kathryn M. Gill, Anthony A. Grace
Publikováno v:
The International Journal of Neuropsychopharmacology. 17:1609-1619
Alteration in normal hippocampal (HPC) function attributed to reduced parvalbumin (PV) expression has been consistently reported in schizophrenia patients and in animal models of schizophrenia. However, it is unclear whether there is an overall loss
Autor:
Hirofumi Morishita, Pascal Steullet, Anthony A. Grace, Anthony S. LaMantia, Michel Cuenod, Joseph T. Coyle, Jan Harry Cabungcal, Urs Meyer, Kathryn M. Gill, Patricio O'Donnell, Kim Q. Do, Lothar Lindemann, Michael Didriksen, Thomas M. Maynard, Hensch Takao, Matthew D. Puhl
Publikováno v:
Schizophrenia Bulletin
Background Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization. Their activity supports critical developmental trajectories, sensory and cognitive pro
Autor:
Anthony A. Grace, Kathryn M. Gill
Publikováno v:
Schizophrenia and Psychotic Spectrum Disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c94c80740f30142447ed106783d27c3
https://doi.org/10.1093/med/9780199378067.003.0010
https://doi.org/10.1093/med/9780199378067.003.0010
Publikováno v:
European Journal of Neuroscience. 35:1312-1321
Stressors can exert a wide variety of responses, ranging from adaptive responses to pathological changes; moreover, recent studies suggest that mild stressors can attenuate the response of a system to major stressful events. We have previously shown