Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kathryn M. Armstrong"'
Publikováno v:
Journal of Molecular Recognition. 21:275-287
αβ T cell receptors (TCR) recognize peptide antigens presented by class I or class II major histocompatibility complex molecules (pMHC). Here we review the use of thermodynamic measurements in the study of TCR-pMHC interactions, with attention to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb85868baf72bf9da04b60c11eb7d431
https://doi.org/10.1002/jmr.896
https://doi.org/10.1002/jmr.896
Autor:
Kathryn M. Armstrong, Brian M. Baker
Publikováno v:
Biophysical Journal. 93(2):597-609
The alphabeta T cell receptor (TCR) is responsible for recognizing peptides bound and "presented" by major histocompatibility complex (MHC) molecules. We recently reported that at 25 degrees C the A6 TCR, which recognizes the Tax peptide presented by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64197f8e7928d07a7f389c7633ff7fc
Autor:
John R. Clemens, Tiffany K. Baxter, Rebecca L. Davis-Harrison, Susan J. Gagnon, William E. Biddison, Richard V. Turner, Kathryn M. Armstrong, Marale Damirjian, Brian M. Baker, Oleg Y. Borbulevych
Publikováno v:
Journal of Molecular Biology. 353:556-573
T cell receptor (TCR) recognition of peptide takes place in the context of the major histocompatibility complex (MHC) molecule, which accounts for approximately two-thirds of the peptide/MHC buried surface. Using the class I MHC HLA-A2 and a large pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13115a5b1c895e01b0fddeca2c50fe4
https://doi.org/10.1016/j.jmb.2005.08.024
https://doi.org/10.1016/j.jmb.2005.08.024
Publikováno v:
Journal of Molecular Biology. 346:533-550
A6 and B7 are two alphabeta T cell receptors (TCRs) that recognize the Tax peptide presented by the class I major histocompatibility molecule HLA-A2 (Tax/HLA-A2). Despite the fact that the two TCRs have different CDR loops and use different amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6e13594897b87363669590452f4013
https://doi.org/10.1016/j.jmb.2004.11.063
https://doi.org/10.1016/j.jmb.2004.11.063
Publikováno v:
Biophysical Journal. 84:238-250
The thickness of monoglyceride planar bilayers has significant effects on the transfer of protons in both native gramicidin A (gA) and in covalently linked SS- and RR-dioxolane-linked gA proteins. Planar bilayers with various thicknesses were formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1529f09633980719ba053440d2d90adf
https://doi.org/10.1016/s0006-3495(03)74845-0
https://doi.org/10.1016/s0006-3495(03)74845-0
Autor:
Kathryn M. Armstrong, Samuel Cukierman
Publikováno v:
Biophysical Journal. 82:1329-1337
The submillisecond closing events (flickers) and the single channel conductances to protons (g(H)) were studied in native gramicidin A (gA) and in the SS and RR diastereoisomers of dioxolane-linked gA channels in planar bilayers. Bilayers were formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec460c06403945f7c9ebf454e5f179ec
https://doi.org/10.1016/s0006-3495(02)75488-x
https://doi.org/10.1016/s0006-3495(02)75488-x
Autor:
Priscilla Do, Kurt H. Piepenbrink, Oleg Y. Borbulevych, John R. Clemens, Kathryn M. Armstrong, Clare Desmond, Ruth F. Sommese, Brian M. Baker
Publikováno v:
The Biochemical journal. 423(3)
TCR (T-cell receptor) recognition of antigenic peptides bound and presented by MHC (major histocompatibility complex) molecules forms the basis of the cellular immune response to pathogens and cancer. TCRs bind peptide–MHC complexes weakly and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555a813c183dd818464a568a2cb6022a
https://pubmed.ncbi.nlm.nih.gov/19698083
https://pubmed.ncbi.nlm.nih.gov/19698083
Publikováno v:
Methods in Enzymology ISBN: 9780123747761
αβ T cell receptors (TCRs) recognize peptide antigens bound and presented by class I or class II major histocompatibility complex (MHC) proteins. Recognition of a peptide/MHC complex is required for initiation and propagation of a cellular immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90507776452e8a82f09cc3721dc0288
https://doi.org/10.1016/s0076-6879(09)66015-8
https://doi.org/10.1016/s0076-6879(09)66015-8
Publikováno v:
Biochemical Journal
A necessary feature of the immune system, TCR (T-cell receptor) cross-reactivity has been implicated in numerous autoimmune pathologies and is an underlying cause of transplant rejection. Early studies of the interactions of alphabeta TCRs (T-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd680adda022adf57e24e00b70e6104
https://pubmed.ncbi.nlm.nih.gov/18800968
https://pubmed.ncbi.nlm.nih.gov/18800968
Autor:
Samuel Cukierman, David S. Crumrine, Edward P. Quigley, Kathryn M. Armstrong, Paulene Quigley
The direct role of the dioxolane group on the gating and single-channel conductance of different stereoisomers of the dioxolane-linked gramicidin A (gA) channels reconstituted in planar lipid bilayers was investigated. Four different covalently linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80516f49ee74a79b910f5e56f75117dc
https://europepmc.org/articles/PMC1301370/
https://europepmc.org/articles/PMC1301370/