Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kathryn M Johnson"'
Autor:
Paula L Hyland, Nan Hu, Melissa Rotunno, Hua Su, Chaoyu Wang, Lemin Wang, Ruth M Pfeiffer, Barbara Gherman, Carol Giffen, Cathy Dykes, Sanford M Dawsey, Christian C Abnet, Kathryn M Johnson, Ruben D Acosta, Patrick E Young, Brooks D Cash, Philip R Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93219 (2014)
Barrett's esophagus (BE) is a metaplastic precursor lesion of esophageal adenocarcinoma (EA), the most rapidly increasing cancer in western societies. While the prevalence of BE is increasing, the vast majority of EA occurs in patients with undiagnos
Externí odkaz:
https://doaj.org/article/f815fea185d14e4597a99cdd0fae801e
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Journal of Cutaneous Pathology. 45:940-943
Cutaneous granulomas without detectable infectious etiology rarely occur in children and adults with primary immunodeficiency disorders. These cutaneous granulomas are primarily seen in combined variable immunodeficiency, ataxia-telangiectasia, and s
Autor:
Jan Petersen, Peter Gräber, Kathryn M. Johnson, Michael Börsch, Gary D. Glick, Ilka Starke, Anthony W. Opipari
Bz-423 is a promising new drug for treatment of autoimmune diseases. This small molecule binds to subunit OSCP of the mitochondrial enzyme FoF1-ATP synthase and modulates its catalytic activities. We investigate the binding of Bz-423 to mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a75022fec69c833c6ef9462bce9ca10
http://arxiv.org/abs/1602.04470
http://arxiv.org/abs/1602.04470
Autor:
Kathryn M. Johnson, Lara Swenson, Carol A. Fierke, Rolf Reuter, Michael Börsch, Nawid Zarrabi, Anthony W. Opipari, Gary D. Glick
Publikováno v:
Biopolymers. 91:830-840
The mitochondrial F(1)F(o)-ATPase performs the terminal step of oxidative phosphorylation. Small molecules that modulate this enzyme have been invaluable in helping decipher F(1)F(o)-ATPase structure, function, and mechanism. Aurovertin is an antibio
Publikováno v:
ACS Chemical Biology. 1:304-308
Altered cellular bioenergetics are implicated in many disease processes, and modulating the F 1 F o -ATPase, the enzyme responsible for producing the majority of ATP in eukaryotic cells, has been proposed to have therapeutic utility. Bz-423 is a 1,4-
Publikováno v:
Journal of Macromolecular Science, Part A. 41:587-611
A novel zwitterionic surfactant monomer containing a carboxybetaine moiety and a 10 carbon aliphatic tail was synthesized and copolymerized with acrylamide to yield a water‐soluble, hydrophobically modified zwitterionic polymer [Poly(acrylamide‐c
Publikováno v:
Journal of Applied Polymer Science. 92:658-671
The interaction of hydrophobically modified (HM) polybetaines with selected small molecule surfactants in aqueous solution was investigated using rheological and surface tension analyses. The polymers included acrylamide-based, HM polybetaines contai
Publikováno v:
Journal of Applied Polymer Science. 92:647-657
Acrylamide-based, hydrophobically modified (HM) polybetaines containing N-butylphenylacrylamide (BPAM) and varying amounts of the sulfobetaine monomer 3-(2-acrylamido-2-methylpropanedimethylammonio)-1-propanesulfonate (AMPDAPS) or the carboxybetaine
Autor:
David A. Mann, Laura L. Kiessling, Kathryn M. Johnson, Michael C. Schuster, William D. Thomas, Tonia J. Buchholz
Publikováno v:
Organic Letters. 5:1407-1410
We have developed methods for the parallel synthesis of two libraries of non-carbohydrate-based analogues of mannose on a solid support. The natural product shikimic acid was used as a key building block. The ability of the compounds to block the bin