Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathryn Leigh Eward"'
Publikováno v:
BioTechniques, Vol 32, Iss 5, Pp 1098-1105 (2002)
A method is described for producing sizable quantities of synchronously dividing, minimally disturbed mammalian cells. Cultures were grown immobilized on surfaces such that cell division within the population resulted in the continuous release of syn
Externí odkaz:
https://doaj.org/article/bd1c63c8794941fcba360de0617fbe03
Autor:
Hyo Il Jung, S. Shreeram, J. Julian Blow, Marco Loddo, Ellen C. Obermann, Craig A Williams, Gareth H. Williams, A Toby Prevost, Thomas R. Fanshawe, Kai Stoeber, Kathryn Leigh Eward
The DNA replication (or origin) licensing system ensures precise duplication of the genome in each cell cycle and is a powerful regulator of cell proliferation in metazoa. Studies in yeast, Drosophila melanogaster and Xenopus laevis have characterise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d4cc9880bda4e137d99994a340db1d
https://doi.org/10.1242/jcs.01503
https://doi.org/10.1242/jcs.01503
Autor:
Kathryn Leigh Eward, Mohammed Ahmed Rashid, Jessica Butcher, Elisabetta Leo, Marco Loddo, Anjana A. Kulkarni, Kai Stoeber, Gareth H. Williams, Alison Frost, Jonathan A. Ledermann, Thomas R. Fanshawe
Publikováno v:
Clinical Cancer Research. 13:6153-6161
Purpose: DNA replication licensing factors and Aurora kinases play critical roles in maintaining genomic integrity. We used multiparameter analyses of these cell cycle regulatory proteins to investigate their role in the progression of epithelial ova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c292f3613e5ff1fe09c1cfa6ad623734
https://doi.org/10.1158/1078-0432.ccr-07-0671
https://doi.org/10.1158/1078-0432.ccr-07-0671
Autor:
D. Levy, D Crimmins, S. Hibberd, Kathryn Leigh Eward, Stephen B. Wharton, Gareth H. Williams, D A Jellinek, Kai Stoeber
Publikováno v:
British Journal of Cancer
The convergence point of growth-signalling pathways that control cell proliferation is the initiation of genome replication, the core of which is the assembly of pre-replicative complexes (pre-RCs), resulting in chromatin being 'licensed' for DNA rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25529d7e5addb6c121b9c8aa9f868f9
https://doi.org/10.1038/sj.bjc.6601949
https://doi.org/10.1038/sj.bjc.6601949
Autor:
Cristina Visintin, Masahiro Okuyama, David L. Selwood, Chris Boshoff, Sarah R. Kingsbury, Kathryn Leigh Eward, Gareth H. Williams, Kai Stoeber, Heike Laman, Elisabetta Leo
Publikováno v:
Nature methods. 4(2)
We designed and synthesized small-molecule mimics of an alpha-helical peptide protein transduction domain (PTD). These small-molecule carriers, which we termed SMoCs, are easily coupled to biomolecules, and efficiently deliver dye molecules and recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd118cccb1dec245909097b36021a466
https://pubmed.ncbi.nlm.nih.gov/17264857
https://pubmed.ncbi.nlm.nih.gov/17264857
Autor:
Ahmet Dogan, Gareth H. Williams, Marco Loddo, Elizabeth A. Paul, Ellen C. Obermann, Philippa Munson, Kathryn Leigh Eward, Kai Stoeber
Publikováno v:
The Journal of pathology. 205(3)
Peripheral B-cell lymphomas representing 90% of lymphoid neoplasms are divided into low- and high-growth fraction lymphomas. Here we investigate regulation of DNA replication licensing during B-cell lymphomagenesis. Combined analysis of origin licens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c834b90aac303db54c06986877f6601
https://pubmed.ncbi.nlm.nih.gov/15682442
https://pubmed.ncbi.nlm.nih.gov/15682442
Publikováno v:
BioTechniques. 32(5)
A method is described for producing sizable quantities of synchronously dividing, minimally disturbed mammalian cells. Cultures were grown immobilized on surfaces such that cell division within the population resulted in the continuous release of syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4385ab9e75744623720afefe1439543e
https://pubmed.ncbi.nlm.nih.gov/12019783
https://pubmed.ncbi.nlm.nih.gov/12019783