Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kathryn L. Wofford"'
Autor:
James P. Harris, Constance J. Mietus, Kevin D. Browne, Kathryn L. Wofford, Carolyn E. Keating, Daniel P. Brown, Brian N. Johnson, John A. Wolf, Douglas H. Smith, Akiva S. Cohen, John E. Duda, D. Kacy Cullen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Closed-head traumatic brain injury (TBI) is induced by rapid motion of the head, resulting in diffuse strain fields throughout the brain. The injury mechanism(s), loading thresholds, and neuroanatomical distribution of affected cells remain poorly un
Externí odkaz:
https://doaj.org/article/6199c5a343c2489d9d4370f3f3f80d33
Autor:
Michael R. Grovola, Nicholas Paleologos, Kathryn L. Wofford, James P. Harris, Kevin D. Browne, Victoria Johnson, John E. Duda, John A. Wolf, D. Kacy Cullen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Each year in the USA, over 2.4 million people experience mild traumatic brain injury (TBI), which can induce long-term neurological deficits. The dentate gyrus of the hippocampus is notably susceptible to damage following TBI, as
Externí odkaz:
https://doaj.org/article/f8323c6205b348998cb2767d10d6535b
Autor:
D. Kacy Cullen, Wisberty J. Gordián-Vélez, Laura A. Struzyna, Dennis Jgamadze, James Lim, Kathryn L. Wofford, Kevin D. Browne, H. Isaac Chen
Publikováno v:
iScience, Vol 21, Iss , Pp 57-67 (2019)
Summary: Reestablishing cerebral connectivity is a critical part of restoring neuronal network integrity and brain function after trauma, stroke, and neurodegenerative diseases. Creating transplantable axon tracts in the laboratory is an unexplored s
Externí odkaz:
https://doaj.org/article/22127a45e185408099f6fe90c5f82d96
Autor:
Laura A. Struzyna, Kevin D. Browne, Justin C. Burrell, Wisberty J. Gordián Vélez, Kathryn L. Wofford, Hilton M. Kaplan, N. Sanjeeva Murthy, H. Isaac Chen, John E. Duda, Rodrigo A. España, D. Kacy Cullen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13985
Parkinson’s disease (PD) affects 1–2% of people over 65, causing significant morbidity across a progressive disease course. The classic PD motor deficits are caused by the degeneration of dopaminergic neurons in the substantia nigra pars compacta
Autor:
D. Kacy Cullen, James P. Harris, John A. Wolf, Victoria E. Johnson, Nicholas Paleologos, Kathryn L. Wofford, Michael R. Grovola, Kevin D. Browne, John E. Duda
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Each year in the USA, over 2.4 million people experience mild traumatic brain injury (TBI), which can induce long-term neurological deficits. The dentate gyrus of the hippocampus is notably susceptible to damage following TBI, as hilar mos
Autor:
John C. O’Donnell, Randel L. Swanson, Kathryn L. Wofford, Michael R. Grovola, Erin M. Purvis, Dmitriy Petrov, D. Kacy Cullen
Publikováno v:
Physiology in Health and Disease ISBN: 9783030958831
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4130188449b1de4c14a285b333a0585e
https://doi.org/10.1007/978-3-030-95884-8_13
https://doi.org/10.1007/978-3-030-95884-8_13
Autor:
Kathryn L. Wofford, Mary E. Putt, Michael R. Grovola, Dayo O. Adewole, Kevin D. Browne, D. Kacy Cullen, John C. O'Donnell
Publikováno v:
Brain Commun
Mild traumatic brain injury affects millions of individuals annually primarily through falls, traffic collisions, or blunt trauma and can generate symptoms that persist for years. Closed-head rotational loading is the most common cause of mild trauma
Autor:
Dennis Jgamadze, H. Isaac Chen, Kevin D. Browne, James Lim, D. Kacy Cullen, Kathryn L. Wofford, Wisberty J. Gordián-Vélez, Laura A. Struzyna
Publikováno v:
iScience, Vol 21, Iss, Pp 57-67 (2019)
iScience
iScience
Summary Reestablishing cerebral connectivity is a critical part of restoring neuronal network integrity and brain function after trauma, stroke, and neurodegenerative diseases. Creating transplantable axon tracts in the laboratory is an unexplored st
Publikováno v:
J Biomed Mater Res A
Monocyte-derived macrophages play a critical role in directing wound pathology following injury. Depending on their phenotype, macrophages also promote tissue regeneration. However, the therapeutic administration of macrophages with a controlled phen
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 9, Pp 1481-1489 (2019)
Neural Regeneration Research
Neural Regeneration Research
Neuroinflammation is initiated as a result of traumatic brain injury and can exacerbate evolving tissue pathology. Immune cells respond to acute signals from damaged cells, initiate neuroinflammation, and drive the pathological consequences over time