Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kathryn L. Post"'
Autor:
Kathryn L. Post, Manuel Belmadani, Payel Ganguly, Fabian Meili, Riki Dingwall, Troy A. McDiarmid, Warren M. Meyers, Caitlin Herrington, Barry P. Young, Daniel B. Callaghan, Sanja Rogic, Matthew Edwards, Ana Niciforovic, Alessandro Cau, Catharine H. Rankin, Timothy P. O’Connor, Shernaz X. Bamji, Christopher J. R. Loewen, Douglas W. Allan, Paul Pavlidis, Kurt Haas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Mutations in PTEN have been associated with various human disease, including autism spectrum disorder (ASD) and cancer. Here, the authors assess the function of 106 PTEN variants in yeast, invertebrate models and cell culture and report that PTEN var
Externí odkaz:
https://doaj.org/article/1edea52849604fc89ff112a464d20e83
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Advances in sequencing technology have led to an explosion in the number of known genetic variants of human genes. A major challenge is to now determine which of these variants contribute to diseases as a result of their effect on gene function. Here
Externí odkaz:
https://doaj.org/article/0d7eed35730249099d13592cfce5a521
Autor:
Muriel Arimon, Shuko Takeda, Kathryn L. Post, Sarah Svirsky, Bradley T. Hyman, Oksana Berezovska
Publikováno v:
Neurobiology of Disease, Vol 84, Iss , Pp 109-119 (2015)
Oxidative stress is a common feature of the aging process and of many neurodegenerative disorders, including Alzheimer's disease. Understanding the direct causative relationship between oxidative stress and amyloid pathology, and determining the unde
Externí odkaz:
https://doaj.org/article/30bdfe0f89ca430a87902e8dcc4ac68e
Autor:
Ashley R, Winslow, Simon, Moussaud, Liya, Zhu, Kathryn L, Post, Katherine L, Post, Dennis W, Dickson, Oksana, Berezovska, Pamela J, McLean
Publikováno v:
Brain. 137:1958-1970
A growing number of PSEN1 mutations have been associated with dementia with Lewy bodies and familial Alzheimer's disease with concomitant α-synuclein pathology. The objective of this study was to determine if PSEN1 plays a direct role in the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0df98f3fcd807de0fbfa9ef3a18e00e
https://doi.org/10.1093/brain/awu119
https://doi.org/10.1093/brain/awu119