Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathryn L. Gilroy"'
Autor:
Daniel J. Turnham, Manisha S. Mullen, Nicholas P. Bullock, Kathryn L. Gilroy, Anna E. Richards, Radhika Patel, Marcos Quintela, Valerie S. Meniel, Gillian Seaton, Howard Kynaston, Richard W. E. Clarkson, Toby J. Phesse, Peter S. Nelson, Michael C. Haffner, John N. Staffurth, Helen B. Pearson
Publikováno v:
Cells, Vol 13, Iss 8, p 673 (2024)
As the treatment landscape for prostate cancer gradually evolves, the frequency of treatment-induced neuroendocrine prostate cancer (NEPC) and double-negative prostate cancer (DNPC) that is deficient for androgen receptor (AR) and neuroendocrine (NE)
Externí odkaz:
https://doaj.org/article/1e39ec5e9d2d4ad899c5d22bfe802b4a
Autor:
Kathryn L Gilroy, Anne Terry, Asif Naseer, Jeroen de Ridder, Amin Allahyar, Weiwei Wang, Eric Carpenter, Andrew Mason, Gane K-S Wong, Ewan R Cameron, Anna Kilbey, James C Neil
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154070 (2016)
Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails in
Externí odkaz:
https://doaj.org/article/fffeecc2b77e4c0dbb2b30242dabfe8a
Autor:
Camille A Huser, Kathryn L Gilroy, Jeroen de Ridder, Anna Kilbey, Gillian Borland, Nancy Mackay, Alma Jenkins, Margaret Bell, Pawel Herzyk, Louise van der Weyden, David J Adams, Alistair G Rust, Ewan Cameron, James C Neil
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004167 (2014)
Retroviral insertional mutagenesis (RIM) is a powerful tool for cancer genomics that was combined in this study with deep sequencing (RIM/DS) to facilitate a comprehensive analysis of lymphoma progression. Transgenic mice expressing two potent collab
Externí odkaz:
https://doaj.org/article/7a389df5dff3498bb3e7704e492e8245
Autor:
Kathryn L Gilroy, Caroline A Austin
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14693 (2011)
BACKGROUND: Type II DNA topoisomerases are essential, ubiquitous enzymes that act to relieve topological problems arising in DNA from normal cellular activity. Their mechanism of action involves the ATP-dependent transport of one DNA duplex through a
Externí odkaz:
https://doaj.org/article/e438b1f03ec34e63be72839ca0ab85ae
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1754 (2008)
Type II DNA topoisomerases (topos) are essential enzymes needed for the resolution of topological problems that occur during DNA metabolic processes. Topos carry out an ATP-dependent strand passage reaction whereby one double helix is passed through
Externí odkaz:
https://doaj.org/article/200534672e7f41eab87f2bd7afbce99f