Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kathryn L. Ball"'
Autor:
Ashita Singh, Monikaben Padariya, Jakub Faktor, Sachin Kote, Sara Mikac, Alicja Dziadosz, Tak W. Lam, Jack Brydon, Martin A. Wear, Kathryn L. Ball, Ted Hupp, Alicja Sznarkowska, Borek Vojtesek, Umesh Kalathiya
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The interferon signalling system elicits a robust cytokine response against a wide range of environmental pathogenic and internal pathological signals, leading to induction of a subset of interferon-induced proteins. We applied DSS (disuccin
Externí odkaz:
https://doaj.org/article/dde10cbfa9fa423d95fc9d4bcdeb1995
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101247- (2022)
Summary: The neuroprotective E3-ubiquitin ligase CHIP is linked to healthy aging. Here, we present a protocol using a patient-derived iPSC line with a triplication of the α-synuclein gene to produce gene-edited cells isogenic for CHIP. We describe i
Externí odkaz:
https://doaj.org/article/9a6047e2764240678c08947604e8d494
Autor:
Catarina Dias, Erisa Nita, Jakub Faktor, Ailish C. Tynan, Lenka Hernychova, Borivoj Vojtesek, Jesper Nylandsted, Ted R. Hupp, Tilo Kunath, Kathryn L. Ball
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103921- (2022)
Externí odkaz:
https://doaj.org/article/184f2fb85b014d7dbde811a7e9b3a77b
Autor:
Ruidong Li, Pavlina Zatloukalova, Petr Muller, Maria Gil-Mir, Sachin Kote, Simon Wilkinson, Alain J. Kemp, Lenka Hernychova, Yaxin Wang, Kathryn L. Ball, Kaixiong Tao, Ted Hupp, Borivoj Vojtesek
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-21 (2020)
Abstract Background The links between the p53/MDM2 pathway and the expression of pro-oncogenic immune inhibitory receptors in tumor cells are undefined. In this report, we evaluate whether there is p53 and/or MDM2 dependence in the expression of two
Externí odkaz:
https://doaj.org/article/b8f9b11009b24fcab0d358372577dfdf
Autor:
Catarina Dias, Erisa Nita, Jakub Faktor, Ailish C. Tynan, Lenka Hernychova, Borivoj Vojtesek, Jesper Nylandsted, Ted R. Hupp, Tilo Kunath, Kathryn L. Ball
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102878- (2021)
Summary: CHIP is an E3-ubiquitin ligase that contributes to healthy aging and has been characterized as neuroprotective. To elucidate dominant CHIP-dependent changes in protein steady-state levels in a patient-derived human neuronal model, CHIP funct
Externí odkaz:
https://doaj.org/article/01017be915b44be0856d83d5615cd1e0
Autor:
Maria Gómez-Herranz, Jakub Faktor, Marcos Yébenes Mayordomo, Magdalena Pilch, Marta Nekulova, Lenka Hernychova, Kathryn L. Ball, Borivoj Vojtesek, Ted R. Hupp, Sachin Kote
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1090 (2022)
The IFITM restriction factors play a role in cancer cell progression through undefined mechanisms. We investigate new protein–protein interactions for IFITM1/3 in the context of cancer that would shed some light on how IFITM1/3 attenuate the expres
Externí odkaz:
https://doaj.org/article/f6ccedfb34244f7587bb5ef5265a4bb5
Autor:
María Eugenia Goya, Feng Xue, Cristina Sampedro-Torres-Quevedo, Sofia Arnaouteli, Lourdes Riquelme-Dominguez, Andrés Romanowski, Jack Brydon, Kathryn L. Ball, Nicola R. Stanley-Wall, Maria Doitsidou
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 367-380.e7 (2020)
Summary: Recent discoveries have implicated the gut microbiome in the progression and severity of Parkinson’s disease; however, how gut bacteria affect such neurodegenerative disorders remains unclear. Here, we report that the Bacillus subtilis pro
Externí odkaz:
https://doaj.org/article/a87257da5bfb470a9a0549aa4440b32f
Autor:
Lukas Uhrik, Kathryn L. Ball, Maciej Parys, David Argyle, Chris Nortcliffe, Barbara C. Ruetgen, Umesh Kalathiya, Borivoj Vojtesek, Pavlína Zatloukalová, Marta Nekulova, Mikolaj Kocikowski, Małgorzata Lisowska, Lenka Hernychová, Jakub Faktor, Ted R. Hupp, Robin Fåhraeus, Petr Müller
Publikováno v:
Uhrik, L, Hernychova, L, Muller, P, Kalathiya, U, Lisowska, M M, Kocikowski, M, Parys, M, Faktor, J, Nekulova, M, Nortcliffe, C, Zatloukalova, P, Ruetgen, B, Fahraeus, R, Ball, K L, Argyle, D J, Vojtesek, B & Hupp, T 2021, ' Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody ', Biochemical Journal, vol. 478, no. 1, pp. 99-120 . https://doi.org/10.1042/BCJ20200674
Biochemical Journal
Biochemical Journal
A comparative canine–human therapeutics model is being developed in B-cell lymphoma through the generation of a hybridoma cell that produces a murine monoclonal antibody specific for canine CD20. The hybridoma cell produces two light chains, light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fb429b05c2a88b64c8dd71f33cada0
https://doi.org/10.1042/bcj20200674
https://doi.org/10.1042/bcj20200674
Autor:
Maria Gómez-Herranz, Jakub Faktor, Marcos Yébenes Mayordomo, Magdalena Pilch, Lenka Hernychova, Kathryn L. Ball, Borivoj Vojtesek, Ted R. Hupp, Sachin Kote
IFITM proteins play a role in cancer cell progression through undefined mechanisms. Here, we propose an emergent role of IFITM1/3 regulating protein synthesis. SBP-tagged IFITM1 protein was used to identify an association of IFITM1 protein with the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d52f5bc32d1a3f2b2f799b2f68def58f
https://doi.org/10.1101/2022.02.02.478792
https://doi.org/10.1101/2022.02.02.478792
Autor:
Andrea D. Lipińska, Michał Rychłowski, Krystyna Bieńkowska-Szewczyk, Maria Gómez-Herranz, Alicja M Chmielewska, Weronika Hoffmann, Ewelina Krol, Marta Nekulova, Małgorzata Tyrakowska, Ted R. Hupp, Richard D Sloan, Paulina Gach, Kathryn L. Ball, Borivoj Vojtesek
Publikováno v:
J Virol
Chmielewska, A M, Gomez Herranz, M, Gach, P, Nekulova, M, Tyrakowska, M, Lipinska, A D, Rychlowski, M, Hoffman, W, Krol, E, Vojtesek, B, Sloan, R D, Bienkowska-Szewczyk, K, Hupp, T R & Ball, K L 2021, ' The role of IFITM proteins in tick-borne encephalitis virus infection ', Journal of Virology . https://doi.org/10.1128/JVI.01130-21
Chmielewska, A M, Gomez Herranz, M, Gach, P, Nekulova, M, Tyrakowska, M, Lipinska, A D, Rychlowski, M, Hoffman, W, Krol, E, Vojtesek, B, Sloan, R D, Bienkowska-Szewczyk, K, Hupp, T R & Ball, K L 2021, ' The role of IFITM proteins in tick-borne encephalitis virus infection ', Journal of Virology . https://doi.org/10.1128/JVI.01130-21
Tick-borne encephalitis virus (TBEV), of the genus Flavivirus, is a causative agent of severe encephalitis in regions of endemicity of northern Asia and central and northern Europe. Interferon-induced transmembrane proteins (IFITMs) are restriction f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d074d249f78759693f7c84e3830a721c
https://europepmc.org/articles/PMC8754218/
https://europepmc.org/articles/PMC8754218/