Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kathryn K Chadman"'
Autor:
Subit Barua, Kathryn K Chadman, Salomon Kuizon, Diego Buenaventura, Nathan W Stapley, Felicia Ruocco, Umme Begum, Sara R Guariglia, W Ted Brown, Mohammed A Junaid
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101674 (2014)
BACKGROUND: Studies have indicated that altered maternal micronutrients and vitamins influence the development of newborns and altered nutrient exposure throughout the lifetime may have potential health effects and increased susceptibility to chronic
Externí odkaz:
https://doaj.org/article/b00a8cdfdb984079b2f86a2be7fe0176
Autor:
Kathryn K. Chadman, Tatyana Adayev, Aishwarya Udayan, Rida Ahmed, Chun-Ling Dai, Jeffrey H. Goodman, Harry Meeker, Natalia Dolzhanskaya, Milen Velinov
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 505
Volume 14
Issue 2
Pages: 505
Background Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and autism. Gene therapy may offer an efficient method to ameliorate the symptoms of this disorder. Methods An AAVphp.eb-hSyn-mFMR1IOS7 vector and an em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61bff2805e242b27e57f0d8d7558458
Autor:
Kathryn K. Chadman, Tatyana Adayev, Aishwarya Udayan, Rida Ahmed, Chun-Ling Dai, Jeffrey H. Goodman, Harry Meeker, Natalia Dolzhanskaya, Milen Velinov
BackgroundFragile X syndrome (FXS) is the most common inherited cause of intellectual disability and autism. Gene therapy may offer an efficient method to ameliorate symptoms of the disorder.MethodsAn AAVphp.eb-hSyn-mFMR1IOS7 vector and an empty cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7d1775c793cf1654eb6c30b56296b3
https://doi.org/10.1101/2022.12.22.520936
https://doi.org/10.1101/2022.12.22.520936
Publikováno v:
Autism Research. 14:1375-1389
Accumulating evidence links dysfunction in the endocannabinoid system (ECS) with the pathology of neurodevelopmental disorders, particularly autism spectrum disorder (ASD). Variants in ECS genes CNR1 and DAGLA are associated with neurological phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16f5240d399e33926ee62422e726c0e
https://doi.org/10.1002/aur.2520
https://doi.org/10.1002/aur.2520
Publikováno v:
Behavioural Brain Research. 437:114132
Autism spectrum disorder (ASD) is characterized by deficits in social communication and repetitive behaviors/restricted interests. One mouse model of ASD is the BTBR T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954b0c831a33fbde71330564139d2b3d
https://doi.org/10.1016/j.bbr.2022.114132
https://doi.org/10.1016/j.bbr.2022.114132
Publikováno v:
Autism Research. 12:1184-1191
BTBR T+ Itpr3tf /J (BTBR) mice have been used as a model of autism spectrum disorder (ASD) due to their low levels of sociability and high levels of repetitive grooming. These experiments explored social behavior in the BTBR and C57BL/6J mice using v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2976990df41fbe49e96cc0dda141fc4
https://doi.org/10.1002/aur.2158
https://doi.org/10.1002/aur.2158
Publikováno v:
Expert Opinion on Drug Discovery. 14:727-734
Introduction: Autism spectrum disorder (ASD) defines impairments in a broad range of behaviors in two domains, social communication and repetitive behaviors and/or restricted interests. Drug discovery is ongoing for ASD, but no drugs have been approv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e5d24fe45d60400201f20930684877
https://doi.org/10.1080/17460441.2019.1621285
https://doi.org/10.1080/17460441.2019.1621285
Pharmacological inhibition of BKCa channels induces a specific social deficit in adult C57BL6/J mice
Publikováno v:
Behavioral neuroscience. 135(4)
Genetic variants in large conductance voltage and calcium sensitive potassium (BKCa) channels have associations with neurodevelopmental disorders such as autism spectrum disorder, fragile X syndrome, and intellectual disability. In the case of fragil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5e99353a60139c5178c85621e8a864
https://pubmed.ncbi.nlm.nih.gov/33734729
https://pubmed.ncbi.nlm.nih.gov/33734729
Autor:
Jarek Wegiel, W. Ted Brown, Kathryn K. Chadman, Shuang Yong Ma, Wojciech Kaczmarski, Thomas Wisniewski, Izabela Kuchna, Michael Flory, Jerzy Wegiel, Krzysztof Nowicki
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 76:225-237
To test the hypothesis that developmental anomalies of the corpus callosum (CC), contribute to the pathogenesis of autism, we characterized the type, topography, and severity of CC pathology corresponding to reduced CC areas that are detected by magn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119d758db3677b9f9e0b680e8db59913
https://doi.org/10.1093/jnen/nlx003
https://doi.org/10.1093/jnen/nlx003
Publikováno v:
Advances in experimental medicine and biology. 1155
Taurine is abundant in various tissues including the brain, muscle, heart, spleen, liver and kidney with various physiological functions. Since taurine is produced by cysteine sulfinic acid decarboxylase (CSAD) in the liver and kidney, taurine-defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22c3f4d2953676b50079630b58f5eaff
https://pubmed.ncbi.nlm.nih.gov/31468456
https://pubmed.ncbi.nlm.nih.gov/31468456