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Autor:
James K. Coward, Kathryn J. Magee, John Galivan, John J. McGuire, William H. Haile, Myung S. Rhee, Wanda E. Bolanowska, Barry P. Hart, Cynthia A. Russell, Brajeswar Paul
Publikováno v:
Biochemical pharmacology. 52(8)
Fluoroglutamate-containing analogs of folates and methotrexate (MTX) with altered capacities for poly (gamma-glutamate) metabolism were synthesized to probe the biological roles of polyglutamates. Compared to folic acid, DL-e,t-gamma-fluorofolic acid