Zobrazeno 1 - 10 of 29 pro vyhledávání: '"Kathryn J. Leyva"'
1
Akademický článek
Biological Effects of HDAC Inhibitors Vary with Zinc Binding Group: Differential Effects on Zinc Bioavailability, ROS Production, and R175H p53 Mutant Protein Reactivation
Autor: Brianna M. Flores, Chandana K. Uppalapati, Agnes S. Pascual, Alan Vong, Margaux A. Baatz, Alisha M. Harrison, Kathryn J. Leyva, Elizabeth E. Hull
Publikováno v: Biomolecules, Vol 13, Iss 11, p 1588 (2023)
The coordination of zinc by histone deacetylase inhibitors (HDACi), altering the bioavailability of zinc to histone deacetylases (HDACs), is key to HDAC enzyme inhibition. However, the ability of zinc binding groups (ZBGs) to alter intracellular free
Externí odkaz: https://doaj.org/article/da81ce2f3c1e4bc2a679b926f4fd18c8
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2
Akademický článek
Complement Factor H in cSCC: Evidence of a Link Between Sun Exposure and Immunosuppression in Skin Cancer Progression
Autor: Ellise M. Johnson, Chandana K. Uppalapati, Agnes S. Pascual, Sarah I. Estrada, Richard L. Averitte, Kathryn J. Leyva, Elizabeth E. Hull
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Cutaneous squamous cell carcinoma (cSCC) is a common form of skin cancer with an estimated 750,000 cases diagnosed annually in the United States. Most cases are successfully treated with a simple excision procedure, but ~5% of cases metastasize and h
Externí odkaz: https://doaj.org/article/b3cd61b1ce8c40d6a8eca8241242022b
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3
A Hybrid Epithelial to Mesenchymal Transition in Ex Vivo Cutaneous Squamous Cell Carcinoma Tissues
Autor: Christopher S. Pulford, Chandana K. Uppalapati, McKale R. Montgomery, Richard L. Averitte, Elizabeth E. Hull, Kathryn J. Leyva
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9183
While most cases of cutaneous squamous cell carcinoma (cSCC) are benign, invasive cSCC is associated with higher mortality and is often more difficult to treat. As such, understanding the factors that influence the progression of cSCC are important.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f210d1abb917242204ff268c1823690
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5
Complement Factor H in cSCC: Evidence of a Link Between Sun Exposure and Immunosuppression in Skin Cancer Progression
Autor: Ellise M. Johnson, Chandana K. Uppalapati, Agnes S. Pascual, Sarah I. Estrada, Richard L. Averitte, Kathryn J. Leyva, Elizabeth E. Hull
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Cutaneous squamous cell carcinoma (cSCC) is a common form of skin cancer with an estimated 750,000 cases diagnosed annually in the United States. Most cases are successfully treated with a simple excision procedure, but ~5% of cases metastasize and h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf5c4039b606425cb90f52f13ccd98
https://pubmed.ncbi.nlm.nih.gov/35223500
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6
Abstract LB022: A hybrid epithelial to mesenchymal transition in ex-vivo cutaneous squamous cell carcinoma tissues
Autor: Christopher S. Pulford, Chandana K. Uppalapati, McKale R. Montgomery, Elizabeth E. Hull, Kathryn J. Leyva
Publikováno v: Cancer Research. 82:LB022-LB022
While most cases of cutaneous squamous cell carcinoma (cSCC) are benign, invasive cSCC is associated with higher mortality and is often more difficult to treat. As such, understanding the factors that influence the progression of cSCC are important.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f1886880fe51d00f606da7f6e3131b3
https://doi.org/10.1158/1538-7445.am2022-lb022
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7
Abstract LB041: Differential response to progranulin in proliferative and metastatic SW13 cell subtypes
Autor: Chika Okonya, McKale R. Montgomery, Agnes S. Pascual, Chandana Uppalapati, Kathryn J. Leyva, Elizabeth E. Hull
Publikováno v: Cancer Research. 82:LB041-LB041
The SW13 human adrenocortical carcinoma line exists in proliferative SW13- and metastatic SW13+ subtypes which interconvert by epigenetic mechanisms in an epithelial to mesenchymal transition (EMT) process. This work investigates the contribution of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac546345bbee8abf9ec4581e642c22b2
https://doi.org/10.1158/1538-7445.am2022-lb041
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8
Dual inhibition of TGFβR and ROCK reverses the epithelial to mesenchymal transition in collectively migrating zebrafish keratocytes
Autor: Elizabeth E. Hull, Chandana K. Uppalapati, Agnes S. Pascual, Kathryn J. Leyva, Kimbal Cooper, Jose L Rapanan
Publikováno v: Cell Biology International
There is a growing controversy about the role of the epithelial to mesenchymal transition (EMT) in the fibrosis associated with chronic disease. Recent studies suggest that it is not the EMT transcriptional program but differentiation of progenitor c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a58198f287ed8e44246d6575b08a93
https://pubmed.ncbi.nlm.nih.gov/33710707
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9
Abstract 1540: Cutaneous squamous cell carcinoma: Evidence of epithelial to mesenchymal transition
Autor: Christopher Pulford, Elizabeth E. Hull, Kathryn J. Leyva, Chandana K. Uppalapati
Publikováno v: Cancer Research. 80:1540-1540
Cutaneous Squamous Cell Carcinoma (cSCC) is the second most common form of skin cancer, frequently arising from sun-induced mutations. Most clinical cases of cSCC are non-invasive and achieve complete cure through tumor excision. However, advanced cS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbede831d81f1ffc1b1c811e403a7fd6
https://doi.org/10.1158/1538-7445.am2020-1540
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