Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kathryn J. Hattersley"'
Autor:
Lauren S. Whyte, Célia Fourrier, Sofia Hassiotis, Adeline A. Lau, Paul J. Trim, Leanne K. Hein, Kathryn J. Hattersley, Julien Bensalem, John J. Hopwood, Kim M. Hemsley, Timothy J. Sargeant
Publikováno v:
IBRO Neuroscience Reports, Vol 12, Iss , Pp 131-141 (2022)
Lysosomal network abnormalities are an increasingly recognised feature of Alzheimer’s disease (AD), which appear early and are progressive in nature. Sandhoff disease and Tay-Sachs disease (neurological lysosomal storage diseases caused by mutation
Externí odkaz:
https://doaj.org/article/d1d4403666e2493b96517b7138797dcc
Autor:
Xiao Tong Teong, Kai Liu, Andrew D. Vincent, Julien Bensalem, Bo Liu, Kathryn J. Hattersley, Lijun Zhao, Christine Feinle-Bisset, Timothy J. Sargeant, Gary A. Wittert, Amy T. Hutchison, Leonie K. Heilbronn
Publikováno v:
Nature Medicine. 29:963-972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47021814cd081a536539f614e2465e30
https://doi.org/10.1038/s41591-023-02287-7
https://doi.org/10.1038/s41591-023-02287-7
Autor:
Lauren S. Whyte, Kim M. Hemsley, John J. Hopwood, Timothy J. Sargeant, Sofia Hassiotis, Kathryn J. Hattersley, Adeline A. Lau
Publikováno v:
Neuroscience. 429:143-155
Lysosomal network dysfunction is a prominent feature of Alzheimer's disease (AD). Although transgenic mouse models of AD are known to model some aspects of lysosomal network dysfunction, the lysosomal network has not yet been examined in the knock-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b081c3dc64ed95b898b0aafaec3343d4
https://doi.org/10.1016/j.neuroscience.2019.12.042
https://doi.org/10.1016/j.neuroscience.2019.12.042
Autor:
Lauren S, Whyte, Célia, Fourrier, Sofia, Hassiotis, Adeline A, Lau, Paul J, Trim, Leanne K, Hein, Kathryn J, Hattersley, Julien, Bensalem, John J, Hopwood, Kim M, Hemsley, Timothy J, Sargeant
Publikováno v:
IBRO neuroscience reports. 12
Lysosomal network abnormalities are an increasingly recognised feature of Alzheimer's disease (AD), which appear early and are progressive in nature. Sandhoff disease and Tay-Sachs disease (neurological lysosomal storage diseases caused by mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb370c3c50a9e2855081f99075512a68
https://pubmed.ncbi.nlm.nih.gov/35146484
https://pubmed.ncbi.nlm.nih.gov/35146484
Autor:
Kathryn J. Hattersley, Julian M. Carosi, Leanne K. Hein, Timothy J. Sargeant, Julien Bensalem
Publikováno v:
Biochemical and biophysical research communications. 570
Degradation and clearance of cellular waste in the autophagic and endo-lysosomal systems is important for normal physiology and prevention of common late-onset diseases such as Alzheimer's disease (AD). Phosphatidylinostol-binding clathrin assembly p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ead4f96fff39238fba73cebd5885b0
https://pubmed.ncbi.nlm.nih.gov/34311200
https://pubmed.ncbi.nlm.nih.gov/34311200
Autor:
Julian M. Carosi, Kathryn J. Hattersley, Julien Bensalem, Timothy J. Sargeant, Leonie K. Heilbronn, Randall H. Grose, Sofia Hassiotis, Célia Fourrier, Leanne K. Hein, Xiao Tong Teong
Publikováno v:
Autophagy
Autophagic flux is a critical cellular process that is vastly under-appreciated in terms of its importance to human health. Preclinical studies have demonstrated that reductions in autophagic flux cause cancer and exacerbate chronic diseases, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c805b12c2cb8c43b93a097a20d47f93
https://hdl.handle.net/11541.2/145225
https://hdl.handle.net/11541.2/145225
Autor:
Valerie Bryksin, Timothy J. Sargeant, Célia Fourrier, Julien Bensalem, Leanne K. Hein, Kathryn J. Hattersley
Publikováno v:
Biochemical and biophysical research communications. 534
Measurement of autophagic flux in vivo is critical to understand how autophagy can be used to combat disease. Neurodegenerative diseases have a special relationship with autophagy, which makes measurement of autophagy in the brain a significant resea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e1c91743d7cb0422e153919ef4af84
https://pubmed.ncbi.nlm.nih.gov/33316543
https://pubmed.ncbi.nlm.nih.gov/33316543
Autor:
Zhe Yang, Timothy J. Sargeant, Kathryn J. Hattersley, Julian M. Carosi, Yi Cui, Rohan D. Teasdale
Publikováno v:
Bio Protoc
The enrichment of lysosomes is a useful way to study their structure and function. These dynamic vesicles can be enriched from cell cultures in a variety of ways including immunoprecipitation and fluorescence-activated organelle sorting. These method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c02975e765e387741fbbf2db2562a7
https://europepmc.org/articles/PMC7854078/
https://europepmc.org/articles/PMC7854078/
Autor:
Lauren S, Whyte, Sofia, Hassiotis, Kathryn J, Hattersley, Kim M, Hemsley, John J, Hopwood, Adeline A, Lau, Timothy J, Sargeant
Publikováno v:
Neuroscience. 429
Lysosomal network dysfunction is a prominent feature of Alzheimer's disease (AD). Although transgenic mouse models of AD are known to model some aspects of lysosomal network dysfunction, the lysosomal network has not yet been examined in the knock-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::215f7138cbd7fdb1c311a78e1052c657
https://pubmed.ncbi.nlm.nih.gov/31917339
https://pubmed.ncbi.nlm.nih.gov/31917339
Autor:
John J. Hopwood, Marten F. Snel, Neil R. Marshall, Sofia Hassiotis, Robert D. Jolly, Kathryn J. Hattersley, Justin N. Tucker, Paul J. Trim, Barbara King, Kim M. Hemsley
Publikováno v:
Journal of Inherited Metabolic Disease. 40:443-453
Intra-cerebrospinal fluid (CSF) injection of recombinant human lysosomal enzyme is a potential treatment strategy for several neurodegenerative lysosomal storage disorders including Sanfilippo syndrome (Mucopolysaccharidosis type IIIA; MPS IIIA). Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894441c1b00eb06de09b9d3ef7a153fa
https://doi.org/10.1007/s10545-016-9994-1
https://doi.org/10.1007/s10545-016-9994-1