Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Kathryn J Jones"'
Autor:
Abhirami Kannan Iyer, Kathryn J Jones
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 4, Pp 562-565 (2017)
Amyotrophic lateral sclerosis (ALS) is a fatal progressive disorder characterized by the selective degeneration of motor neurons (MN). The impact of peripheral immune status on disease progression and MN survival is becoming increasingly recognized i
Externí odkaz:
https://doaj.org/article/313de4a1758547b5be94a7b0c0eaa0de
Autor:
Melissa M Haulcomb, Rena M Meadows, Whitney M Miller, Kathryn P McMillan, MeKenzie J Hilsmeyer, Xuefu Wang, Wesley T Beaulieu, Stephanie L Dickinson, Todd J Brown, Virginia M Sanders, Kathryn J Jones
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 10, Pp 1664-1679 (2017)
Amyotrophic lateral sclerosis is a motoneuron degenerative disease that is challenging to diagnose and presents with considerable variability in survival. Early identification and enhanced understanding of symptomatic patterns could aid in diagnosis
Externí odkaz:
https://doaj.org/article/b04a1782a8fc44b6b41fcc1c3a0ff7f6
Autor:
Ying Wang, Wei Wu, Xiangbing Wu, Yan Sun, Yi P Zhang, Ling-Xiao Deng, Melissa Jane Walker, Wenrui Qu, Chen Chen, Nai-Kui Liu, Qi Han, Heqiao Dai, Lisa BE Shields, Christopher B Shields, Dale R Sengelaub, Kathryn J Jones, George M Smith, Xiao-Ming Xu
Publikováno v:
eLife, Vol 7 (2018)
Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10) contusive
Externí odkaz:
https://doaj.org/article/8a30e0b29f914c39a805040cd8856858
Autor:
Derek A Wainwright, Junping Xin, Nichole A Mesnard, Taylor R Beahrs, Christine M Politis, Virginia M Sanders, Kathryn J Jones
Publikováno v:
ASN Neuro, Vol 1 (2009)
We have previously demonstrated a neuroprotective mechanism of FMN (facial motoneuron) survival after facial nerve axotomy that is dependent on CD4 + Th2 cell interaction with peripheral antigen-presenting cells, as well as CNS (central nervous syste
Externí odkaz:
https://doaj.org/article/16a9610410a1434b86c5988385041b20
Autor:
Elizabeth M. Runge, Deborah O. Setter, Abhirami K. Iyer, Eric J. Regele, Felicia M. Kennedy, Virginia M. Sanders, Kathryn J. Jones
Publikováno v:
Cells, Vol 11, Iss 19, p 3167 (2022)
Facial motoneuron (FMN) survival is mediated by CD4+ T cells in an interleukin-10 (IL-10)-dependent manner after facial nerve axotomy (FNA), but CD4+ T cells themselves are not the source of this neuroprotective IL-10. The aims of this study were to
Externí odkaz:
https://doaj.org/article/43b57b1dd9e84abb8cbbc99bf2a90fae
Autor:
Elizabeth M. Runge, Morgan M. Sandelski, Chandler L. Walker, Sarah M. Drejet, Brandon L. Brown, Kathryn J. Jones, Taha Z. Shipchandler
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 5, Iss 3, Pp 552-559 (2020)
Laryngoscope Investigative Otolaryngology
Laryngoscope Investigative Otolaryngology
Objectives To determine whether functional and anatomical outcomes following suture neurorrhaphy are improved by the addition of electrical stimulation with or without the addition of polyethylene glycol (PEG). Methods In a rat model of facial nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7bc4547a06ff159c9b61212c7deac5
https://doi.org/10.1002/lio2.411
https://doi.org/10.1002/lio2.411
Autor:
Elizabeth M. Runge, Deborah O. Setter, Abhirami K. Iyer, Virginia M. Sanders, Kathryn J. Jones, Felicia M. Kennedy
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Background After peripheral nerve transection, facial motoneuron (FMN) survival depends on an intact CD4+ T cell population and a central source of interleukin-10 (IL-10). However, it has not been determined previously whether CD4+ T cells participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bd44fc4224c93616d47dddd5bc44c7
http://europepmc.org/articles/PMC7164177
http://europepmc.org/articles/PMC7164177
Autor:
Taylor Beahrs, Virginia M. Sanders, Sara K. Custer, Nicole D. Schartz, Deborah O. Setter, Melissa M. Haulcomb, Rena M. Meadows, Kathryn J. Jones
Publikováno v:
Restorative Neurology and Neuroscience. 36:417-422
BACKGROUND When nerve transection is performed on adult rodents, a substantial population of neurons survives short-term disconnection from target, and the immune system supports this neuronal survival, however long-term survival remains unknown. Und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b711f74e76f63c497eefd44ed9f3f81a
https://doi.org/10.3233/rnn-170809
https://doi.org/10.3233/rnn-170809
Publikováno v:
Curr Opin Urol
Purpose of review The present review highlights regenerative electrical stimulation (RES) as potential future treatment options for patients with nerve injuries leading to urological dysfunction, such as urinary incontinence, voiding dysfunction or e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c647a06f17e72d4fd32d0c0caddb0946
https://pubmed.ncbi.nlm.nih.gov/30985344
https://pubmed.ncbi.nlm.nih.gov/30985344
Autor:
Elizabeth M. Runge, Kathryn J. Jones, Felicia M. Kennedy, Virginia M. Sanders, Eric J. Regele
Publikováno v:
Proceedings of IMPRS. 1
Background and Hypothesis: It is unknown how the immune system maintains the majority of facial motoneuron (FMN) survival after axotomy. IL-10 cytokine is necessary for FMN survival and CD4+ T cells are activated and play a critical role in survival,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f997ebbca778f67d3f8ca6946fcdafc1
https://doi.org/10.18060/22748
https://doi.org/10.18060/22748