Zobrazeno 1 - 10
of 483
pro vyhledávání: '"Kathryn J, Wood"'
Autor:
Sunil K. Ahuja, Muthu Saravanan Manoharan, Grace C. Lee, Lyle R. McKinnon, Justin A. Meunier, Maristella Steri, Nathan Harper, Edoardo Fiorillo, Alisha M. Smith, Marcos I. Restrepo, Anne P. Branum, Matthew J. Bottomley, Valeria Orrù, Fabio Jimenez, Andrew Carrillo, Lavanya Pandranki, Caitlyn A. Winter, Lauryn A. Winter, Alvaro A. Gaitan, Alvaro G. Moreira, Elizabeth A. Walter, Guido Silvestri, Christopher L. King, Yong-Tang Zheng, Hong-Yi Zheng, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Keith R. Fowke, Paul N. Harden, Kathryn J. Wood, Martin T. Ferris, Jennifer M. Lund, Mark T. Heise, Nigel Garrett, Kristen R. Canady, Salim S. Abdool Karim, Susan J. Little, Sara Gianella, Davey M. Smith, Scott Letendre, Douglas D. Richman, Francesco Cucca, Hanh Trinh, Sandra Sanchez-Reilly, Joan M. Hecht, Jose A. Cadena Zuluaga, Antonio Anzueto, Jacqueline A. Pugh, South Texas Veterans Health Care System COVID-19 team, Brian K. Agan, Robert Root-Bernstein, Robert A. Clark, Jason F. Okulicz, Weijing He
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-31 (2023)
Abstract Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined as the capacity to preserve and/
Externí odkaz:
https://doaj.org/article/2d05c47c46834fc38503fbfb37c7eb1f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMalignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR
Externí odkaz:
https://doaj.org/article/2e927d849d85448eb416c3488db47965
Autor:
Yue Gu, Robynne W. K. Koh, May Ling Lai, Denise Pochinco, Rachel Z. C. Teo, Marieta Chan, Tanusya M. Murali, Chong Wai Liew, Yee Hwa Wong, Nicholas R. J. Gascoigne, Kathryn J. Wood, Julien Lescar, Peter Nickerson, Paul A. MacAry, Anantharaman Vathsala
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract The current state-of-the-art technology employed to assess anti-human leukocyte antigen antibodies (Anti-HLA Ab) for donor-recipient matching and patient risk stratification in renal transplantation is the single antigen bead (SAB) assay. Ho
Externí odkaz:
https://doaj.org/article/0d892bb6ce394324a9db08fda50ac687
Autor:
Yue Gu, Yee Hwa Wong, Chong Wai Liew, Conrad E. Z. Chan, Tanusya M. Murali, Jiawei Yap, Chien Tei Too, Kiren Purushotorman, Maryam Hamidinia, Abbas El Sahili, Angeline T. H. Goh, Rachel Z. C. Teo, Kathryn J. Wood, Brendon J. Hanson, Nicholas R. J. Gascoigne, Julien Lescar, Anantharaman Vathsala, Paul A. MacAry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Anti-human leukocyte antigen (HLA) antibodies are important mediators of alloresponses, but structural insights on antibody:HLA interaction are still lacking. Here the authors provide a 2.4 Å structure of antibody:HLA complex, and also analyse HLA f
Externí odkaz:
https://doaj.org/article/d43685122a4b496da7e60656bb9c199a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory T cells (Tregs) can control excessive or undesirable immune responses toward autoantigens, alloantigens, and pathogens. In transplantation, host immune responses against the allograft are suppressed through the use of immunosuppressive dru
Externí odkaz:
https://doaj.org/article/bedada1b6b1041839bd85722dabd6e74
Publikováno v:
Clinical Immunology ISBN: 9780702081651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60306f1f169a6d7c3d0e36f4e63f3807
https://doi.org/10.1016/b978-0-7020-8165-1.00089-7
https://doi.org/10.1016/b978-0-7020-8165-1.00089-7
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundT follicular helper (Tfh) cells are key players in the production of antibody-producing B cells via the germinal center reaction. Therapeutic strategies targeting Tfh cells are important where antibody formation is implicated in disease, su
Externí odkaz:
https://doaj.org/article/f3e3bbcc13a64f44bd99b159209cc91d
Autor:
José L. Cohen, Kathryn J. Wood
Publikováno v:
OncoImmunology, Vol 7, Iss 1 (2018)
Three recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allog
Externí odkaz:
https://doaj.org/article/dee55a28ea0645ad900d0e2c41c7d71a
Autor:
Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medi
Externí odkaz:
https://doaj.org/article/6e6307c0ff3e4a65bfd0edfff5a979c4
Autor:
Gilles Blancho, Maria Meneghini, Magali Giral, Edoardo Melilli, Juan Irure, Martina Koch, Miriam C. Banas, Elena Crespo, Raphaël Duivenvoorden, Cécile Braudeau, Anett Sefrin, Kathryn J. Wood, Friedrich Thaiss, Oriol Bestard, Bernhard Banas, Petra Hruba, Petra Reinke, Frederike J. Bemelman, Björn Nashan, Sophie Brouard, Nils Lachmann, Natalie M Otto, Alberto Sanchez-Fueyo, Maik Stein, Liu Hu, Lucia Stranavova, Ondrej Viklicky, H.-D. Volk, Josep M. Grinyó, Gantuja Bold, Sophia Christakoudi, Juan Carlos Ruiz
Publikováno v:
American Journal of Transplantation, 21, 8, pp. 2833-2845
American journal of transplantation, 21(8), 2833-2845. Wiley-Blackwell
American Journal of Transplantation, 21, 2833-2845
American journal of transplantation, 21(8), 2833-2845. Wiley-Blackwell
American Journal of Transplantation, 21, 2833-2845
Item does not contain fulltext Personalizing immunosuppression is a major objective in transplantation. Transplant recipients are heterogeneous regarding their immunological memory and primary alloimmune susceptibility. This biomarker-guided trial in